Results 161 to 170 of about 2,877,856 (360)
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Patient Referral and Pressure Injuries: A Systematic Review
Aims To analyse and discuss the basic conditions and related factors of transported patients' PIs and attract the attention of healthcare providers to PIs. Design Systematic review.
Yahan Wang +5 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Occupational therapists’ judgement of referral priorities: Expertise and training
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The British government currently requires mental health services to be targeted at the most needy (Department of Health, 1999).
Harries, Priscilla Ann
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Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Assessment of Awareness and Practice of General Dentists Regarding the Diagnosis, Treatment, and Referral of Patients with Periodontal Diseases in 2022–2023 [PDF]
Introduction: Periodontal diseases rank among the most prevalent oral health issues and significantly contribute to the onset of systemic conditions.
Mehdi Qadiri Sardasht +2 more
doaj
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Ohio's core knowledge and competencies
Title from PDF cover (viewed on July 12, 2010).; "Ohio Department of Job and Family Services [and] Department of Education; Ohio Child Care Resource & Referral Association; Ohio Professional Development Network"--P. 4 of cover.; "Published September 2009"
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