Results 111 to 120 of about 5,154,441 (261)

Refinable Kernels

, 2007
Motivated by mathematical learning from training data, we introduce the notion of refinable kernels. Various characterizations of refinable kernels are presented.
Yuesheng Xu, Haizhang Zhang
core  

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

The T₂ structure of polycrystalline cubic human insulin. [PDF]

Acta Crystallogr D Struct Biol, 2023
Triandafillidis DP, Karavassili F, Spiliopoulou M, Valmas A, Athanasiadou M, Nikolaras G, Fili S, Kontou P, Bowler MW, Chasapis CT, Von Dreele RB, Fitch AN, Margiolaki I.   +12 more
europepmc   +1 more source

Fractional GP refinable functions [PDF]

, 2007
A new class of refinable functions extending the GP class introduced in [12] is presented. It is characterized by a symbol with fractional exponent that gives rise to non-compactly supported refinable functions.
PEZZA, Laura
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Site-occupancy factors in the Debye scattering equation. A theoretical discussion on significance and correctness. [PDF]

Acta Crystallogr A Found Adv, 2023
Ferri F, Bossuto MC, Anzini P, Cervellino A, Guagliardi A, Bertolotti F, Masciocchi N.   +6 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

REFINABLE STEP FUNCTION ON LOCAL FIELDS OF POSITIVE CHARACTERISTIC AND ALGORITHM FOR CONSTRUCTING SUCH FUNCTION

, 2020
212-215В работе приводится алгоритм построения ступенчатой масштабирующей функции с компактным носителем на локальных полях положительной характеристики.The algorithm for constructing compactly supported refinable step function on local fields of ...
Крусс Юлия Сергеевна
core