Results 81 to 90 of about 728 (254)
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
The Sobolev regularity of refinable functions [PDF]
, 1997 Refinable functions underlie the theory and constructions of wavelet systems on the one hand, and the theory and convergence analysis of uniform subdivision algorithms. The regularity of such functions dictates, in the context of wavelets, the smoothness
Amos Ron, Zuowei Shen
core
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Refinable function vectors are usually given in the form of an infinite product of their refinement (matrix) masks in the frequency domain and approximated by a cascade algorithm in both time and frequency domains.
Zuowei Shen
core
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
On the regularity of refinable functions [PDF]
, 2006 Thesis (MSc (Mathematical Sciences. Physical and Mathematical Analysis))--University of Stellenbosch, 2006.This work studies the regularity (or smoothness) of continuous finitely supported refinable functions which are mainly encountered in ...
Onwunta, Akwum A.
core
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Properties of Locally Linearly Independent Refinable Function Vector
, 2001 The paper considers properties of compactly supported, locally linearly independent refinable function vectors = ( 1 ; : : : ; r ) , r 2 IN. In the first part of the paper, we show that the interval endpoints of the global support of , = 1; : : : ;
D.-X. Zhou, G. Plonka
core