Results 41 to 50 of about 157,821 (303)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Isogeometric analysis for free vibration of bidirectional functionally graded plates in the fluid medium

open access: yesDefence Technology, 2022
This paper for first time proposes an isogeometric analysis (IGA) for free vibration response of bi-directional functionally graded (BDFG) rectangular plates in the fluid medium.
Quoc-Hoa Pham   +3 more
doaj   +1 more source

On the area operators of the Husain-Kuchar-Rovelli model and Canonical/Loop Quantum Gravity [PDF]

open access: yes, 1998
I investigate the relation between an operative definition of the area of a surface specified by matter fields and the area operators recently introduced in the canonical/loop approach to Quantum Gravity and in Rovelli's variant of the Husain-Kuchar ...
Bohr N.   +3 more
core   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Flexure of Thick Plates Resting on Elastic Foundation Using Two-Variable Refined Plate Theory

open access: yesArchive of Mechanical Engineering, 2015
Wpublikacji wykorzystano udoskonalona teorie płyty z dwiema zmiennymi do analizy grubych płyt spoczywajacych na sprezystym podłozu. Teoria ta, która zawiera tylko dwa nieznane parametry, pozwala przewidziec paraboliczna zmiennosc naprezen scinajacych.
Rouzegar Jafar, Sharifpoor Reza Abdoli
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Thermo-electrical buckling response of actuated functionally graded piezoelectric nanoscale plates

open access: yesResults in Physics, 2019
In this work, the analytical investigation of thermo-electrical buckling of a functionally graded piezoelectric nanoscale plate is obtained via a refined hyperbolic higher-order shear deformation theory.
Ashraf M. Zenkour, Maryam H. Aljadani
doaj   +1 more source

Static and dynamic behaviors of laminated composite plates resting on elastic foundation

open access: yesJournal of Building Materials and Structures, 2022
This present study consists to analyze the mechanical buckling and the free vibration stabilities of antisymmetric cross-ply and angle-ply laminated composite plates using a refined high order shear deformation theory of four variables against five in ...
Tahir Ghazoul   +2 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Wave Dispersion Analysis of Functionally Graded GPLs-Reinforced Sandwich Piezoelectromagnetic Plates with a Honeycomb Core

open access: yesMathematics, 2022
This paper studies wave propagation in a new structure composed of three layers. The upper and lower layers are made of a piezoelectromagnetic material reinforced with graphene platelets (GPLs) that may be uniformly disseminated or continuously varied ...
Mohammed Sobhy, Fatemah H. H. Al Mukahal
doaj   +1 more source

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