Results 61 to 70 of about 6,238,485 (295)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Buckling of composite laminates subjected to In-plane partial edge compression using a refined plate theory

, 2006
Copyright © 2006 SAGE Publications The buckling of composite laminates subjected to in-plane partial edge compression is studied using a refined plate theory.
Sheikh, A., Chakrabarti, A.
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Buckling analysis of thick plates using refined trigonometric shear deformation theory

Journal of Materials and Engineering Structures, 2015
In this paper, a refined trigonometric shear deformation plate theory is applied for the buckling analysis of thick isotropic square and rectangular plates.
Sachin Madhavrao Gunjal, Rajesh Baburao Hajare, Atteshamuddin Shamshuddin Sayyad, Manas Dipak Ghodle   +3 more
doaj  

Bending of functionally graded plates via a refined quasi-3D shear and normal deformation theory

Curved and Layered Structures, 2018
Bending of functionally graded plate with two reverse simply supported edges is studied based upon a refined quasi three-dimensional (quasi-3D) shear and normal deformation theory using a third-order shape function.
Zenkour Asharf M., Alghanmi Rabab A.
doaj   +1 more source

Evaluation of the Best New Cross-ply Laminated Plate Theories through the Axiomatic/Asymptotic Approach [PDF]

Journal of Applied and Computational Mechanics, 2018
This paper presents Best Theory Diagrams (BTDs) constructed from various non-polynomial theories for the static analysis of thick and thin symmetric and asymmetric cross-ply laminated plates. The BTD is a curve that provides the minimum number of unknown
S. Candiotti, J.L. MANTARI
doaj   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

The Refined Theory of One-Dimensional Quasi-Crystals in Thick Plate Structures

, 2011
For one-dimensional quasi-crystals, the refined theory of thick plates is explicitly established from the general solution of quasi-crystals and the Luré method without employing ad hoc stress or deformation assumptions.
Yang Gao, Andreas Ricoeur
core   +1 more source

Thermal Buckling Analysis of Laminated Composite Plates Using Four-Variable Refined Plate Theory

Journal of Engineering
This paper investigates the thermal buckling of laminated composite plates based on a refined plate theory that incorporates four variables, using hyperbolic and polynomial shear strain functions for the first time to analyze thermal buckling of a ...
Ahmed Khamees Sabea , Widad Ibraheem Majeed   +1 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source