Results 231 to 240 of about 5,714,792 (303)

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

moTSart: accelerating automated transition state search with generative models in a low-data regime.

Digit Discov
Galustian L, Karwounopoulos J, Demuth T, De Landsheere J, Mark K, Kovar MP, Zamyatin A, Svatunek D, Heid E.   +8 more
europepmc   +1 more source

Theorizing How Context Influences School-Based Interventions That Support Children's Weight Management: Co-Producing a Refined Logic Model. [PDF]

J Particip Med
Kneale D, Edwards RC, Khatwa M, Nguyen PT, Saleem S, Chaires S, Richardson L, Bennett V, Evans T, O'Mara-Eves A.   +9 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

A Realist Review Protocol on the Contribution of  Mental Health First Aider Programmes to Staff Wellbeing within Hospital and associated healthcare settings. [PDF]

HRB Open Res
Donegan D, Teeling SP, McNamara M.
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

How environmental cues shape human face value perceptions-an exploration based on grounded theory. [PDF]

Front Psychol
Chen L, Yang C, Li Y, Luo Y.
europepmc   +1 more source

Updates of the Status Quo of Situation-Specific Theories (2015-2025). [PDF]

J Nurs Scholarsh
Kim D, Im EO.
europepmc   +1 more source