Results 101 to 110 of about 756,391 (343)
R³Net: Recurrent Residual Refinement Network for Saliency Detection
International Joint Conference on Artificial Intelligence, 2018 Saliency detection is a fundamental yet challenging task in computer vision, aiming at highlighting the most visually distinctive objects in an image.
Zijun Deng +6 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
, 2020 As a technical term in Computer Science, “refinement” is understood as a relation between systems (programs, channels.. ) that, in its most austere form, is simply preservation of properties. © Springer Nature Switzerland AG 2020.
Alvim, M.S. +5 more
openaire +3 more sources
Humane Endpoints in Swiss Webster Mice Infected with Toxoplasma gondii RH Strain
AnimalsThe highly virulent Toxoplasma gondii RH strain is maintained through successive passages in mice, but there is still a lack of studies that refine these procedures from a 3Rs perspective, where humanitarian ideals aim to minimize the stress, pain, or ...
Igor Falco Arruda +7 more
doaj +1 more source
Use of intensity quotients and differences in absolute structure refinement
Acta Crystallographica. Section B: Structural Science, Crystal Engineering and Materials, 2013 Differences and quotients can be defined using Friedel pairs of reflections and applied in refinement to enable absolute structure to be determined precisely even for light atom crystal structures.
S. Parsons, H. Flack, T. Wagner
semanticscholar +1 more source
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Journal of Investigative Surgery, 2019 The 34th Annual Meeting of the Academy of Surgical Research was held from September 26–28, 2018 in Charleston, South Carolina. The Academy’s community joins together at the annual meeting to promote and advance professional and academic standards ...
Melanie L. Graham +2 more
doaj +1 more source
Comparison of hair steroid levels among Wistar rats exposed to different environmental enrichment settings [PDF]
Veterinary WorldBackground and Aim: Environmental enrichment (EE) is a pivotal tool for creating ideal housing conditions that allow animals to fully display their ethograms.
Alberto Elmi +7 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source