Results 111 to 120 of about 1,353,441 (297)

Adaptive Mesh Refinement for Singular Current Sheets in Incompressible Magnetohydrodynamic Flows

, 1996
The formation of current sheets in ideal incompressible magnetohydrodynamic flows in two dimensions is studied numerically using the technique of adaptive mesh refinement. The growth of current density is in agreement with simple scaling assumptions.
Beale, Bell, Bell, Bell, Bell, Berger, Biskamp, Christiane Marliani, Frisch, Grauer, Grauer, Holger Friedel, Kerr, Pumir, Pumir, Rainer Grauer, Sulem   +16 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Neural Network Based Model Refinement [PDF]

In this paper, model bases and model generators are presented in the context of model refinement. This article proposes a neural network based model refinement technique for software metrics estimation.
Adrian VISOIU
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Refined Quadripartitioned, Refined Pentapartitioned, Refined Heptapartitioned, and Iterative Refined Neutrosophic Logic

A Neutrosophic Set models uncertainty via three memberships—truth, indeterminacy, and falsity. We develop an n–Refined Neutrosophic Logic (n–RNL) that splits these into interpretable subcomponents and define refined quadripartitioned, pentapartitioned, and heptapartitioned families capturing contradiction, ignorance, unknown, and relative truth/falsity.
openaire   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Diagonal Matrix Reduction over Refinement Rings

پژوهش‌های ریاضی, 2022
: A ring R is called a refinement ring if the monoid of finitely generated projective R- modules is refinement.  Let R be a commutative refinement ring and M, N, be two finitely generated projective R-nodules, then M~N  if and only if Mm ~Nm for all ...
Marjan Sheibani Abdolyousefi, Raham Bahmani Sangesari, Nahid Ashrafi   +2 more
doaj  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source