Results 121 to 130 of about 553,328 (316)
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Refinement-aware generation of attack trees
, 2017 © Springer International Publishing AG 2017. Attack trees allow a security analyst to obtain an overview of the potential vulnerabilities of a system.
O Gadyatskaya (13534243) +4 more
core
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
STUDIES REGARDING THE WEAR OF THE TOOLS USED IN RUBBER REFINEMENT [PDF]
Fiabilitate şi Durabilitate, 2011 The paper presents the results obtained in the study of tools wear that occurs when used in therefining of rubber and solutions to reduce the level of the wear. Thus the wear that occurs in this type of tool is adimensional one, but also one of corrosion
Dan Dobrotă,, Alin Nioaţă,
doaj
New approaches to casting hypereutectic Al-Si alloys to achieve simultaneous refinement of primary silicon and modification of eutectic silicon [PDF]
, 2013 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel UniversityHypereutectic Al-Si alloys are of increasing interest for applications that require a combination of light weight and high wear resistance, such as pistons ...
Al-Helal, Kawther
core
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Refinement-based verification of interactive real-time systems
, 2008 Formal specification provides a system description that is much more precise than the natural language one and it can help to solve a lot of specification problems.
Maria Spichkova (18025924)
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
A Neutrosophic Set models uncertainty via three memberships—truth, indeterminacy, and falsity. We develop an n–Refined Neutrosophic Logic (n–RNL) that splits these into interpretable subcomponents and define refined quadripartitioned, pentapartitioned, and heptapartitioned families capturing contradiction, ignorance, unknown, and relative truth/falsity.
openaire +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source