Results 51 to 60 of about 84,271 (219)

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

One-Shot Box-Centric Teaching for Persistent Robotic Sorting-and-Filling with Relative Pose Constraints

Sensors
Robotic sorting-and-filling tasks in flexible manufacturing require robots to reproduce specified in-box arrangements while adapting to variations in container poses, object availability, sensing conditions, and external interventions.
Wei Du, Jianhua Wu
doaj   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

Geocoding Refinement via Planar Block Adjustment for Spaceborne SAR Imagery in Low-Relief Terrain: A Case Study of LuTan-1

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
The geolocation accuracy of spaceborne synthetic aperture radar (SAR) imagery is crucial for a wide range of applications, yet it is often degraded by errors in onboard parameters, making accurate geocoding refinement essential.
Kefu Wu, Haiqiang Fu, Jianjun Zhu, Qijin Han, Aichun Wang, Mingxia Zhang, Huacan Hu, Dong Zeng, Zhiwei Liu, Zhiwei Li, Yang Liu   +10 more
doaj   +1 more source

Advancing Stroke Clinical Trials Using Community Engagement and Implementation Science Approaches

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Stroke clinical trials are essential for advancing stroke care but can face challenges with recruitment, retention, clinical relevance, and translation into real‐world practice. We propose that integrating community engagement and implementation science approaches into stroke trials can help address these needs.
Lesli E. Skolarus, Devin L. Brown, Bernadette Boden‐Albala   +2 more
wiley   +1 more source

Phantom-Free Geometric Refinement for Industrial CBCT Using Physical Constraints and a Normalized Low-Rank Projection Prior

Sensors
Geometric misalignment degrades industrial cone-beam computed tomography (CBCT), particularly when a dedicated calibration phantom cannot be deployed during object acquisition.
Yanxu Sun, Xingyuan Bian, Igor A. Konyakhin, Junning Cui   +3 more
doaj   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif, Diane Demailly, Gabriella A. Horvàth, Juan Dario Ortigoza Escobar, Nathalie Dorison, Mayté Castro Jiménez, Cécile A. Hubsch, Thomas Wirth, Gun‐Marie Hariz, Sophie Huby, Morgan Dornadic, Zohra Souei, Muhammad Mushhood Ur Rehman, Simone Hemm, Mehdi Boulaymen, Eduardo M. Moraud, Jocelyne Bloch, Xavier Vasques   +17 more
wiley   +1 more source

Stabilization of video sequence from board of a small UAV based oncovariance search for reference points with prediction

Весці Нацыянальнай акадэміі навук Беларусі: Серыя фізіка-тэхнічных навук, 2016
A covariance method of video sequence stabilization with prediction is proposed. It based on matching of covariance wavelet features and gradual refinement of reference areas locations.
I. A. Baryskievic, V. Yu. Tsviatkou
doaj  

A Viscous Boundary Layer Mesh Adaptation Method and Its Application in High-Angle-of-Attack Separated Flows

Applied Sciences
Adjoint-based mesh adaptation method serves as an effective approach to improve the predictive accuracy of aerodynamic characteristics. However, viscous boundary layer grids often encounter issues such as hanging nodes, negative volumes, and directional ...
Pengcheng Cui, Xiaojun Wu, Jiangtao Chen, Hongyin Jia, Fan Qin, Jie Zhang, Yaobing Zhang, Guiyu Zhou, Jing Tang   +8 more
doaj   +1 more source

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael   +22 more
wiley   +1 more source