Results 41 to 50 of about 32,927 (306)

On the exceptional damage-tolerance of gradient metallic materials [PDF]

, 2020
An experimental study is described on the fracture toughness and micro-mechanisms associated with the initiation and propagation of cracks in metallic nickel containing marked gradients in grain size, ranging from ∼30 nm to ∼4 μm.
Cao, R, Li, Y, Lin, Y, Pan, J, Ritchie, RO, Sweet, A, Yu, Q   +6 more
core  

Soil geohazard mapping for improved asset management of UK local roads [PDF]

, 2015
Unclassified roads comprise 60% of the road network in the United Kingdom (UK). The resilience of this locally important network is declining. It is considered by the Institution of Civil Engineers to be “at risk” and is ranked 26th in the world ...
Farewell, Timothy S., Hallett, Stephen H., Pritchard, Oliver G.   +2 more
core   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

THE EFFECT OF RECLAIM TIRE RUBBER AS ADDITIVE IN MINIMIZING REFLECTIVE CRACKING

Diyala Journal of Engineering Sciences, 2010
The rehabilitation of cracked pavement by overlaying, without any improvement, is rarely a durable solution, as the cracks rapidly propagate through the new asphalt layer.
HANAA KHALEEL A. AL-BAITI
doaj   +1 more source

Performance of TenCate Paving Interlayers in Asphalt Concrete Pavements [PDF]

, 2017
As a continued effort of a previously completed project entitled “Performance of TenCate Mirafi PGM-G4 Interlayer-Reinforced Asphalt Pavements in Alaska,” this project evaluated two newly modified paving interlayers (TruPave and Mirapave) through overlay,
Li, Lin, Liu, Jenny, Zhao, Sheng
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Discussion on Road Reflection Crack and Control

IOP Conference Series: Materials Science and Engineering, 2020
Abstract This paper focused on the problems encountered in the road construction of a coal-fired power plant in the Philippines as an example. Some cracks and damage appeared in the roadbed after the road concrete base layer has been built.
Huifang Zhao, Hongbo Li
openaire   +1 more source

Review of reflective cracking in composite pavements

International Journal of Pavement Research and Technology, 2020
Reflective cracking is identified as the main weakness of composite pavement in airfield and highways forcing the authorities to devote a large portion of their budget to rehabilitation and/or reconstruction of the existing composite pavements. It is, therefore, very important to have a better understanding of the reflective cracking mechanism to ...
Sahar Deilami, G. White
openaire   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Cracking Characteristics of Different Crack Forms in Pavement under Moving Load

Engineering Transactions
In road engineering, the crack damage problems are one of the essential research areas that need to be emphasized. However, there have been few researches on the effects caused by different crack forms, e.g., the impacts of the distribution and ...
Guannan YAN
doaj   +1 more source