Results 41 to 50 of about 33,060 (306)

Innovative approach in the stabilisation of coastal slopes [PDF]

, 2018
Coastal slope instability poses a risk to life and material properties and is of great concern in times of climate change, posing challenges as communities seek to adapt and ensure resilience.
Mickovski, Slobodan B., Thomson, Craig S.   +1 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

THE EFFECT OF RECLAIM TIRE RUBBER AS ADDITIVE IN MINIMIZING REFLECTIVE CRACKING

Diyala Journal of Engineering Sciences, 2010
The rehabilitation of cracked pavement by overlaying, without any improvement, is rarely a durable solution, as the cracks rapidly propagate through the new asphalt layer.
HANAA KHALEEL A. AL-BAITI
doaj   +1 more source

Performance of TenCate Paving Interlayers in Asphalt Concrete Pavements [PDF]

, 2017
As a continued effort of a previously completed project entitled “Performance of TenCate Mirafi PGM-G4 Interlayer-Reinforced Asphalt Pavements in Alaska,” this project evaluated two newly modified paving interlayers (TruPave and Mirapave) through overlay,
Li, Lin, Liu, Jenny, Zhao, Sheng
core  

Neural Networks Modeling of Stress Growth in Asphalt Overlays due to Load and Thermal Effects during Reflection Cracking [PDF]

, 2011
Although several techniques have been introduced to reduce reflective cracking, one of the primary forms of distress in hot-mix asphalt (HMA) overlays of flexible and rigid pavements, the underlying mechanism and causes of reflective cracking are not yet
Ceylan, Halil, Ceylan, Halil, Gopalakrishnan, Kasthurirangan, Lytton, Robert   +3 more
core   +3 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Continued Field Evaluation of Precutting for Maintaining Asphalt Concrete Pavements with Thermal Cracking [PDF]

, 2017
In continuation of a previously completed project entitled Evaluate Presawn Transverse Thermal Cracks for Asphalt Concrete Pavement, this project was a further effort to understand important variables in the thermal cracking process through continued ...
Liu, Jenny, McHattie, Robert, Zhao, Sheng   +2 more
core  

Discussion on Road Reflection Crack and Control

IOP Conference Series: Materials Science and Engineering, 2020
Abstract This paper focused on the problems encountered in the road construction of a coal-fired power plant in the Philippines as an example. Some cracks and damage appeared in the roadbed after the road concrete base layer has been built.
Huifang Zhao, Hongbo Li
openaire   +1 more source

Review of reflective cracking in composite pavements

International Journal of Pavement Research and Technology, 2020
Reflective cracking is identified as the main weakness of composite pavement in airfield and highways forcing the authorities to devote a large portion of their budget to rehabilitation and/or reconstruction of the existing composite pavements. It is, therefore, very important to have a better understanding of the reflective cracking mechanism to ...
Sahar Deilami, G. White
openaire   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source