Results 141 to 150 of about 1,720,003 (286)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Epistemological belief, reflective thinking and mathematics interest as a predictor of students’ mathematics performance: mediation analysis via structural equation modeling (SEM)

open access: yesCogent Education
This study aimed to investigates the mediating roles of of mathematics interest in the nexus between epistemological belief, reflective thinking, and students’ mathematics performance. This study employed a cross‐sectional survey design.
Bright Asare
doaj   +1 more source

Pupil dilation and cognitive reflection as predictors of performance on the Iowa Gambling Task [PDF]

open access: yes, 2017
Risky decisions and implicit learning involve both cognitive and emotional factors. As the primary test-bed for the Somatic Marker Hypothesis (SMH), the Iowa Gambling Task (IGT) was devised to examine these factors.
Gale, Maggie   +3 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Opening minds, fostering reflection: A pathway analysis of open-mindedness and reflective thinking skills in science education

open access: yesSocial Sciences and Humanities Open
Open-mindedness has been extensively researched and plays a significant role as a moderator in students' reasoning abilities; however, its correlation with or role in reflective thinking skills remains unexplored.
Pipih Nurhayati   +3 more
doaj   +1 more source

Reflective thinking practices among secondary school Mathematics Teachers. [PDF]

open access: yes, 2008
The purpose of the study was to identify the practice of reflective thinking among secondary school mathematics teachers in the teaching and learning process.
Elias, Habibah   +3 more
core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

The Role of the Reflective Thinking Scale for International Students in China Through Factor Analysis

open access: yesBehavioral Sciences
Reflective thinking is crucial for academic success, personal development, and cultural adaptation. Therefore, this study aimed to analyze the role of the Reflective Thinking Scale (RTS) for international students in Chinese universities.
Jiangtao Fu, Ali Usman Hali
doaj   +1 more source

‘Do not block the way of inquiry’: cultivating collective doubt through sustained deep reflective thinking. [PDF]

open access: yes, 2018
We provide a Camusian/Peircean notion of inquiry that emphasises an attitude of fallibilism and sustained epistemic dissonance as a conceptual framework for a theory of classroom practice founded on Deep Reflective Thinking (DTR), in which the ...
Burgh, Gilbert   +2 more
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy