Results 111 to 120 of about 613,638 (295)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Entering into dialogue with the taboo: Reflective writing in a social work human sexuality course

open access: yesJournal of Writing Research, 2012
This paper examines a unique reflective writing assignment used in an undergraduate social work course on human sexuality. We ask what new understandings reflective writing mediates (Vygotsky, 1978) regarding sexual orientation, gender identity, and ...
Heather Killelea McEntarfer, David Skiba & Sarah A. Robert
doaj  

The Presence and Possibility of Moral Sensibility in Beginning Pre-Service Teachers [PDF]

open access: yes, 2007
This paper presents research on the moral sensibility of six pre-service teachers in an undergraduate teacher education program. Using their reflective writing across their first two semesters of coursework as well as focus group interviews in their ...
Burant, Terry J.   +2 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Student Perspectives on Reflective Writing, Improvisation, and Cooperative and Peer Learning in a Collegiate Aural Skills Course [PDF]

open access: yes, 2014
Student-centered instructional approaches that directly engage the learner in problem-solving activities and emphasize social interaction in the construction of knowledge are known to be much more effective than traditional teaching methods.
Morgan, Jenny   +2 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The utility of an online discussion board for reflective writing in an emergency medicine rotation. [PDF]

open access: yesAEM Educ Train, 2023
Pandit K   +8 more
europepmc   +1 more source

Curriculum development practice [PDF]

open access: yes, 2008
This paper discusses the subject of curriculum development. More specifically the paper discusses involvement with curriculum development in teaching and adopts a reflective writing ...
Fearon, Dom
core  

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