Results 71 to 80 of about 152,149 (307)

B cell reductive therapy with rituximab in the treatment of rheumatoid arthritis. [PDF]

open access: yes, 2009
The approach to treating autoimmune disorders is currently undergoing a significant change in focus. As therapies are developed that are more precise in targeting the pathogenesis for these diseases, patients experience significantly fewer side effects ...
Sands, Jacob, Tuscano, Joseph M
core   +2 more sources

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji   +13 more
wiley   +1 more source

The Brain and the Bladder: Forebrain Control of Urinary (In)Continence

open access: yesFrontiers in Physiology, 2020
Neural circuits extending from the cerebral cortex to the bladder maintain urinary continence and allow voiding when it is socially appropriate. Injuries to certain brain regions produce a specific disruption known as urge incontinence.
Margaret M. Tish, Joel C. Geerling
doaj   +1 more source

Neuropathy - gait changes in the diabetic foot [PDF]

open access: yes, 2008
Motor neuropathy in patients with diabetes can lead to weakness in the muscles of the foot and lower leg, which in turn can lead to characteristic changes to the structure of the foot, such as an altered arch profile.
McIntosh, Caroline, Newton, Veronica
core  

Cortical pain responses in human infants [PDF]

open access: yes, 2006
Despite the recent increase in our understanding of the development of pain processing, it is still not known whether premature infants are capable of processing pain at a cortical level.
Boyd, S   +6 more
core   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang   +10 more
wiley   +1 more source

Reflex Inhibition of the Human Quadriceps in the Presence of Knee Joint Damage [PDF]

open access: yesPhysiotherapy, 1988
Quadriceps weakness can occur by atrophy and by reflex inhibition due to stimuli from a damaged knee joint. The mechanisms by which quadriceps weakness occurs are not understood enough to allow weakness to be prevented. The nature of reflex inhibition has been studied in patients undergoing arthrotomy and meniscectomy in order to find ways of ...
openaire   +3 more sources

A Novel Percutaneous Surgical Approach Using Silicone Sheets for Lower Eyelid Lengthening: A Descriptive Case Series

open access: yesPlastic and Reconstructive Surgery, Global Open
Background:. Lower eyelid lengthening is essential to correct eyelid retraction and preserve ocular surface integrity. We evaluated the efficacy of a novel percutaneous surgical technique that utilizes a silicone sheet to elongate the lower eyelids to ...
Shinsuke Kinoshita, MD   +4 more
doaj   +1 more source

Assessment of the peripheral microcirculation using computer-assisted venous congestion plethysmography in post-traumatic complex regional pain syndrome type I [PDF]

open access: yes, 2001
In complex regional pain syndrome type I (CRPS-I), edema of the affected limb is a common finding. Therefore, the changes in macro- and microcirculatory parameters were investigated to elucidate the underlying pathophysiology.
Christ, Frank   +4 more
core   +1 more source

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