Results 91 to 100 of about 171,261 (332)

Proton pump inhibitor concomitant use to prevent oxaliplatin‐induced peripheral neuropathy: Clinical retrospective cohort study

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, EarlyView.
Abstract Background Oxaliplatin‐induced peripheral neuropathy (OIPN) is a major clinical challenge because it leads to discontinuation of chemotherapy. Omeprazole, a proton pump inhibitor (PPI), has been shown to prevent OIPN in a rat model. Therefore, we aimed to test whether the concomitant use of a PPI reduces oxaliplatin discontinuation due to OIPN.
Keisuke Mine, Takehiro Kawashiri, Kohei Mori, Yusuke Mori, Haruna Ishida, Hibiki Kudamatsu, Shunsuke Fujita, Mayako Uchida, Takaaki Yamada, Nobuaki Egashira, Ichiro Ieiri, Satoru Koyanagi, Shigehiro Ohdo, Takao Shimazoe, Daisuke Kobayashi   +14 more
wiley   +1 more source

Dietary guideline adherence for gastroesophageal reflux disease. [PDF]

, 2014
BackgroundGastroesophageal reflux disease (GERD) is the most common gastrointestinal disease, and the cost of health care and lost productivity due to GERD is extremely high.
Block, Gladys, Buffler, Patricia, Corley, Douglas A, Kubo, Ai, Quesenberry, Charles P   +4 more
core   +2 more sources

Esophageal and Oropharyngeal Dysphagia: Clinical Recommendations From the United European Gastroenterology and European Society for Neurogastroenterology and Motility

United European Gastroenterology Journal, EarlyView.
ABSTRACT Dysphagia is a prevalent symptom of the upper gastrointestinal tract causing health related consequences, impacting quality of life and is associated with global economic burden. Swallowing difficulties are classified into oropharyngeal dysphagia (OD) and esophageal dysphagia.
Amir Mari, Francesco Calabrese, Andrea Pasta, Greta Lorenzon, Bas Weusten, Jutta Keller, Pierfrancesco Visaggi, Sabine Roman, Elisa Marabotto, Ram Dickman, Jordi Serra, Nicola De Bortoli, Paola Iovino, Daniel Pohl, Dan Dumitrascu, Mentore Ribolsi, Claudia Barber, Serhat Bor, Mark Fox, Rami Sweiss, Vicente Lorenzo‐Zuniga, Filiz Akyuz, Matteo Ghisa, Altay Celebi, Fahmi Shibli, Rainer Dziewas, Ismail Hakkı Kalkan, Jan Tack, Pere Clavé, Silvia Carrion, Ivy Cheng, Noemi Tomsen, Omar Ortega, Sergio Marin Rubio, Nicole Pizzorni, Emilia Michou, Julie Regan, Shaheen Hamdy, Nathalie Rommel, Martina Scharitzer, Olle Ekberg, Antonio Schindler, Renee Speyer, Anna Gillman, Frank Zerbib, Edoardo V. Savarino   +45 more
wiley   +1 more source

Dickkopf-1, the Wnt antagonist, is induced by acidic pH and mediates epithelial cellular senescence in human reflux esophagitis.

American Journal of Physiology - Gastrointestinal and Liver Physiology, 2014
Squamous esophageal epithelium adapts to acid reflux-mediated injury by proliferation and differentiation via signal transduction pathways. Induction of the Wnt antagonist Dickkopf-1 (Dkk1) is involved in tissue repair during inflammation and cellular ...
O. Lyros, P. Rafiee, L. Nie, Rituparna Medda, Nebojša Jovanović, Jamie L Schmidt, A. Mackinnon, Nanda Venu, R. Shaker   +8 more
semanticscholar   +1 more source

Focal myasthenia gravis in a 4‐year‐old Chihuahua cross dog presented for apparent vomiting

Veterinary Record Case Reports, EarlyView.
Abstract A 4‐year‐old, female, neutered Chihuahua cross was presented with a history of chronic apparent vomiting and coughing. Upon further questioning, regurgitation was suspected rather than vomiting. Conscious thoracic radiographs revealed generalised megaoesophagus.
Martyn A. Wray, Robert E. Shiel, Pedro J. Guzmán Ramos   +2 more
wiley   +1 more source

Foregut microbiome in development of esophageal adenocarcinoma [PDF]

, 2010
Esophageal adenocarcinoma (EA), the type of cancer linked to heartburn due to gastroesophageal reflux diseases (GERD), has increased six fold in the past 30 years. This cannot currently be explained by the usual environmental or by host genetic factors.
Aaron Tenney, Carlos W. Nossa, Daniel Brami, Eoin L. Brodie, Erika Gerz, Fritz Francois, Gary L. Andersen, Indresh K. Singh, Karen E. Nelson, Les Foster, Liying Yang, Manolito Torralba, Mathangi Thiagarajan, Mengling Liu, Michael Poles, Monika Bihan, Morris Traube, Navjeet Singh, Pinak Shah, Shibu Yooseph, Stuart M. Brown, Sukhleen Bedi, Tamasha Parsons, Todd Z. DeSantis, William E. Oberdorf, Yu Chen, Yu-Hui Rogers, Zhiheng Pei   +27 more
core   +2 more sources

Suspected congenital oesophageal stenosis in a cat

Veterinary Record Case Reports, EarlyView.
Abstract A 6‐week‐old, female, British shorthair cat was presented with a 4‐week history of regurgitation and a 2‐day history of cough and dyspnoea. Thoracic radiographs revealed an alveolar pattern suggestive of pneumonia secondary to regurgitation, and antibiotic therapy was initiated. After identifying a smooth stenosis with no signs of inflammation
Charline Fauquet, Patricia Meynaud, Caroline Didier, Fabrice Conchou, Tiphaine Blanchard, Rachel Lavoué, Armelle Diquélou   +6 more
wiley   +1 more source

Genetic polymorphisms of CYP2C19 and IL1B have no influence on esomeprazole treatment for mild erosive esophagitis

Kaohsiung Journal of Medical Sciences, 2015
Interleukin (IL)-1β is a potent inhibitor of gastric acid secretion and its genetic polymorphism is linked to the severity of reflux esophagitis. Proton-pump inhibitor (PPI) metabolized by P450 2C19 (CYP2C19) is the chief medication in reflux esophagitis
Wen-Hung Hsu, Fu-Chen Kuo, Huang-Ming Hu, Ping-I Hsu, Deng-Chyang Wu, Chao-Hung Kuo   +5 more
doaj   +1 more source

Gastroprotective effects of methanolic extract of kratom leaves on gastric ulcer and reflux esophagitis in rats [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2018
Kratom (Mitragyna speciosa (Korth.) Havil.) is a tropical tree indigenous to Thailand. In traditional medicine, it has been used to treat diarrhea, peptic ulcer, stomach ache or gastric upsets.
Somsmorn Chittrakarn, Nisaudah Radenahmad, Sujitra Kaewsara, Wandee Udomuksorn, Niwat Keawpradub, Pimpimol Phukpattaranont   +5 more
doaj   +1 more source

Gastroesophageal resection and anastomosis in a dog with a caudal oesophageal leiomyoma with subsequent fluoroscopic oesophagram

Veterinary Record Case Reports, EarlyView.
Abstract This case report describes the clinical presentation, diagnostic evaluation, surgical technique and postoperative treatment of a 10‐year‐old castrated male mixed breed dog that was presented for lethargy and hyporexia with pale mucous membranes, a heart murmur and melena. Bloodwork demonstrated a regenerative anaemia, and a computed tomography
Kara Anderson, Laura Selmic, Julie Byron, Arin Cox, Hunter J. Piegols   +4 more
wiley   +1 more source