Results 91 to 100 of about 173,987 (367)

Animal Model of Acid-Reflux Esophagitis: Pathogenic Roles of Acid/Pepsin, Prostaglandins, and Amino Acids

BioMed Research International, 2014
Esophagitis was induced in rats within 3 h by ligating both the pylorus and transitional region between the forestomach and glandular portion under ether anesthesia.
K. Takeuchi, Kenji Nagahama
semanticscholar   +1 more source

Genetic polymorphisms of CYP2C19 and IL1B have no influence on esomeprazole treatment for mild erosive esophagitis

Kaohsiung Journal of Medical Sciences, 2015
Interleukin (IL)-1β is a potent inhibitor of gastric acid secretion and its genetic polymorphism is linked to the severity of reflux esophagitis. Proton-pump inhibitor (PPI) metabolized by P450 2C19 (CYP2C19) is the chief medication in reflux esophagitis
Wen-Hung Hsu, Fu-Chen Kuo, Huang-Ming Hu, Ping-I Hsu, Deng-Chyang Wu, Chao-Hung Kuo   +5 more
doaj   +1 more source

Laryngopharyngeal Reflux: The Impact of Obesity

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT This article provides an overview of gastro‐esophageal (GERD) and laryngopharynegal (LPRD) reflux diseases in the context of obesity as a confounding entity. A detailed review of the clinical presentation, pathogenesis, diagnosis, and treatment of laryngopharyngeal reflux disease may be found elsewhere.
Abdul Latif H. Hamdan, Mary J. Hawkshaw, Robert T. Sataloff   +2 more
wiley   +1 more source

Gastroprotective effects of methanolic extract of kratom leaves on gastric ulcer and reflux esophagitis in rats [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2018
Kratom (Mitragyna speciosa (Korth.) Havil.) is a tropical tree indigenous to Thailand. In traditional medicine, it has been used to treat diarrhea, peptic ulcer, stomach ache or gastric upsets.
Somsmorn Chittrakarn, Nisaudah Radenahmad, Sujitra Kaewsara, Wandee Udomuksorn, Niwat Keawpradub, Pimpimol Phukpattaranont   +5 more
doaj   +1 more source

Characterization of bacterial biota in the distal esophagus of Japanese patients with reflux esophagitis and Barrett’s esophagus

BMC Infectious Diseases, 2013
BackgroundThe distal esophagus harbors a complex bacterial population. We hypothesized that a better understanding of bacterial communities in the esophagus would facilitate understanding of the role of bacteria in esophageal disease.
Ning Liu, T. Ando, K. Ishiguro, O. Maeda, O. Watanabe, K. Funasaka, Masanao Nakamura, R. Miyahara, N. Ohmiya, H. Goto   +9 more
semanticscholar   +1 more source

Development and Application of a Functional Human Esophageal Mucosa Explant Platform to Eosinophilic Esophagitis. [PDF]

, 2019
There is an increasing prevalence of esophageal diseases but intact human tissue platforms to study esophageal function, disease mechanisms, and the interactions between cell types in situ are lacking.
Aceves, Seema S, Adejumobi, Dolapo, Akuthota, Praveen, Dohil, Ranjan, Duong, Loan D, Jones, Stacie M, Kurten, Richard C, Levy, Rebecca, Newbury, Robert O, Rawson, Renee, Rothenberg, Marc E, Shoda, Tetsuo, Wright, Benjamin L   +12 more
core   +3 more sources

Chinese Guidelines for Diagnosis and Treatment of Chronic Rhinosinusitis (2024)

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Chronic rhinosinusitis (CRS), a complex inflammatory disease with heterogeneous pathogenesis, demands evolving evidence‐based strategies. Since the 2018 Chinese guidelines and EPOS2020, international advances in CRS immunopathology and biologics have revolutionized therapeutic approaches, particularly through phenotype–endotype classification ...
Subspecialty Group of Rhinology, Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery, Subspecialty Group of Rhinology, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association   +4 more
wiley   +1 more source

Effect of Helicobacter pylori Eradication on Reflux Esophagitis Therapy: A Multi-center Randomized Control Study

Chinese Medical Journal, 2015
Background: Helicobacter pylori (H. pylori) frequently colonizes the stomach. Gastroesophageal reflux disease (GERD) is a common and costly disease. But the relationship of H. pylori and GERD is still unclear. This study aimed to explore the effect of H.
Yan Xue, Li-Ya Zhou, San-Ren Lin, Xiao-Hua Hou, Zhao-Shen Li, Min-Hu Chen, Xiu-E Yan, Ling-Mei Meng, Jing Zhang, Jing-Jing Lu   +9 more
doaj   +1 more source

Background Factors of Reflux Esophagitis and Non-Erosive Reflux Disease: A Cross-Sectional Study of 10,837 Subjects in Japan

PLoS ONE, 2013
Background Despite the high prevalence of gastroesophageal reflux disease (GERD), its risk factors are still a subject of controversy. This is probably due to inadequate distinction between reflux esophagitis (RE) and non-erosive reflux disease (NERD ...
C. Minatsuki, N. Yamamichi, Takeshi Shimamoto, Hikaru Kakimoto, Yu Takahashi, M. Fujishiro, Yoshiki Sakaguchi, Chiemi Nakayama, Maki Konno‐Shimizu, Rie Matsuda, S. Mochizuki, I. Asada‐Hirayama, Y. Tsuji, S. Kodashima, S. Ono, Keiko Niimi, Toru Mitsushima, K. Koike   +17 more
semanticscholar   +1 more source

Causal Relationships Between Gastroesophageal Reflux Disease and Myocardial Infarction: Insights From Univariable and Multivariable Mendelian Randomization Analyses

Annals of Human Genetics, EarlyView.
ABSTRACT Background Observational studies have indicated that gastroesophageal reflux disease (GERD) is connected to myocardial infarction (MI). Nonetheless, the question of causality in these relationships remains unresolved, given the potential influence of confounding variables.
Xiaoya Zheng, Teng Hu, Tianxiang Fang, Pengpeng Su, Yingsong Wang, Ning Huangfu   +5 more
wiley   +1 more source