Role of Potassium-competitive Acid Blockers in the Treatment of Gastric Acid-related Disorders [PDF]
Owing to their superior pharmacokinetic and pharmacodynamic profiles, potassium-competitive acid blockers (P-CABs) score over proton pump inhibitors (PPIs) in the treatment of gastric acid-related disorders and may provide clinical benefit in the ...
Mun Young Cho, Yu Kyung Cho
doaj +1 more source
Gastroprotective effects of methanolic extract of kratom leaves on gastric ulcer and reflux esophagitis in rats [PDF]
Kratom (Mitragyna speciosa (Korth.) Havil.) is a tropical tree indigenous to Thailand. In traditional medicine, it has been used to treat diarrhea, peptic ulcer, stomach ache or gastric upsets.
Somsmorn Chittrakarn +5 more
doaj +1 more source
Esophagitis in a high H. pylori prevalence area: severe disease is rare but concomitant peptic ulcer is frequent. [PDF]
BACKGROUND: Few data are available on the prevalence of erosive and severe esophagitis in Western countries. OBJECTIVE: To retrospectively determine the prevalence and the factors predicting erosive esophagitis and severe esophagitis in a large series of
Julio Ponce +5 more
doaj +1 more source
Histamine H2 receptor antagonists (H2RAs) suppress gastric acid production by blocking H2 receptors in parietal cells. Studies have shown that proton pump inhibitors (PPIs) are superior to H2RAs as a treatment for acid-related disorders, such as peptic ...
Cheol Min Shin
doaj +1 more source
A Narrative Review on Efficacy and Safety of Proton Pump Inhibitors in Children
Proton pump inhibitors (PPIs) are among the most prescribed drugs worldwide and include omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole.
Valeria Dipasquale +3 more
doaj +1 more source
Prevalence of Helicobacter pylori in patients with gastro-oesophageal reflux disease : systematic review. [PDF]
Objectives: To ascertain the prevalence of Helicobacter pylori in patients with gastro-oesophageal reflux disease and its association with the disease.
Childs, S. +3 more
core +2 more sources
Radial distribution of dilated intercellular spaces of the esophageal squamous epithelium in patients with reflux disease exhibiting discrete endoscopic lesions [PDF]
Introduction: Dilatation of intercellular spaces of the esophageal squamous epithelium has been suggested as a marker of early acid reflux-induced damage. This change is a potentially useful addition to histomorphological changes that represent so called
Delarive, J. (J.) +10 more
core +7 more sources
Endoscopic evaluation of patients with dyspepsia in a secondary referral hospital in Egypt
Background: Dyspepsia is a common clinical problem. More than half of patients presenting with dyspepsia have no detectable lesion for their symptoms. The common organic causes of dyspepsia include peptic ulcer, esophagitis and cancer.
Ahmed Gado +3 more
doaj +1 more source
An evaluation of 605 endoscopic examination in a rural setting, Lacor Hospital in Northern Uganda [PDF]
Introduction: The aim of this study was to evaluate the profile of esophagogastroduodenal (EGDS) diseases diagnosed by upper endoscopy in a rural area of Uganda in a retro-protective study of 605 patients.
Alema NO +3 more
core +1 more source
Background and Aim The aim of the present study was to examine the lifestyle‐ and comorbidity‐related determinant factors of the prescription of proton pump inhibitors (PPIs) for patients in whom Helicobacter pylori has been eradicated, and to evaluate ...
Furitsu Shimada +13 more
doaj +1 more source

