Results 31 to 40 of about 9,181 (228)

Pharmacogenetics of proton pump inhibitors

open access: yesМедицинский совет, 2015
Proton pump inhibitors (PPI) are currently the most effective class of antisecretory drugs widely used in the treatment of non-ulcer dyspepsia, reflux esophagitis and GERD, peptic ulcer disease and H. pilory infection, as well as NSAID-associated gastric
M. V. Leonova
doaj   +1 more source

The influence of CYP2C19 polymorphism on the effectiveness of the treatment of acid-dependent diseases

open access: yesМедицинский совет, 2022
Introduction. In modern systematic reviews, there is a point of view that CYP2C19 polymorphism affects the results of treatment of peptic ulcer, erosive esophagitis and eradication of Helicobacter pylori.Оbjective.
V. V. Tsukanov   +6 more
doaj   +1 more source

The Pathophysiology Gastroesophageal Reflux Disease [PDF]

open access: yes, 2007
The incidence of Gastroesophageal Reflux Disease (GERD), especially in Indonesia, is increasing with the change of community life-style. Also, the doctors\u27 perception in understanding clinical manifestation of GERD is alike in addition to the ...
Simadibrata, M. (Marcellus)   +2 more
core   +1 more source

The Benefits of Combination Therapy with Esomeprazole and Rebamipide in Symptom Improvement in Reflux Esophagitis: An International Multicenter Study

open access: yesGut and Liver, 2016
Background/AimsTo investigate the effects of esomeprazole and rebamipide combination therapy on symptomatic improvement in patients with reflux esophagitis.Methods : A total of 501 patients with reflux esophagitis were randomized into one of the ...
Su Jin Hong   +18 more
doaj   +1 more source

Paradigm shift in Etiology of Upper Gastrointestinal Bleed in Emergency Department

open access: yesJournal of Renal and Hepatic Disorders, 2021
Background and Aims: Acute upper gastrointestinal (UGI) bleed is an emergency requiring immediate intervention. Recent data have shown peptic ulcer disease (PUD) to be commonest cause of UGI bleed. We aimed to evaluate all patients of UGI bleed reporting
Tarana Gupta, Sandeep Goyal
doaj   +1 more source

Lack of Effect of H2-Receptor Antagonists and Antacids on the Gastric and Duodenal Gastrin-, Somatostatin- and Serotonin-Producing Cells in Patients with Acid Peptic Disorders

open access: yesCanadian Journal of Gastroenterology, 1996
Standard therapeutic approaches to acid peptic disorders have dealt with neutralizing or inhibiting aggressive factors and/or bolstering defensive factors.
WR Yacoub   +3 more
doaj   +1 more source

Precise role of H pylori in duodenal ulceration [PDF]

open access: yes, 2006
The facts that H pylori infection is commoner in duodenal ulcer (DU) patients than in the normal population, and that eradication results in most cases being cured, have led to the belief that it causes DU. However, early cases of DU are less likely than
Hobsley, M, Holton, J, Tovey, FI
core   +1 more source

Peptic ulcer disease: Insights and risk factors

open access: yesJPGN Reports, EarlyView.
Abstract Objectives Peptic ulcer disease (PUD), affects adults and children, with Helicobacter pylori (H. pylori) infection being the most frequent cause. Diagnosis requires an upper gastrointestinal endoscopy (UGE) and invasive tests. However, besides H. pylori, risk factors for PUD in children remain unclear.
Haidar Houmani   +6 more
wiley   +1 more source

The preventive effect of β adrenoceptor stimulation against experimentally induced reflux esophagitis [PDF]

open access: yes, 2015
A β adrenoceptor agonist plays an important regulatory role in stimulation of thermogenesis and lipolysis and it appears to have anti-ulcer and spasmolytic effects.
Malek, H.A., Shalaby, A.
core   +1 more source

Gastric duplication cyst causing hypergastrinemia in an infant

open access: yesJPGN Reports, EarlyView.
Abstract Gastric duplication cysts are rare congenital anomalies, with fewer than 10% occurring in the stomach. We report a 14‐month‐old girl presenting with failure to thrive, recurrent emesis, hematemesis, and severe duodenitis with ulceration. Laboratory evaluation revealed marked hypergastrinemia (1781 pg/mL), and initial imaging was unrevealing ...
Nathan Bryan, Ian Leibowitz
wiley   +1 more source

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