Results 31 to 40 of about 33,298 (174)
Impact of routine POOGD with routine biopsies on surgical management in 423 patients undergoing RYGB. ABSTRACT Introduction The role of routine preoperative oesophagogastroduodenoscopy (POOGD) with routine biopsies prior to Roux‐en‐Y gastric bypass (RYGB) remains controversial.
Shahab Valizadehzare, Michael Hatzifotis
wiley +1 more source
Helicobacter pylori and the management of gastro-oesophageal reflux disease [PDF]
This thesis is centred on the current controversy and possible links between H. pylori and GORD and whether the infection should be eradicated in those requiring long PPIs.
Raghunath, Anathakrishnapuram Srinivasan
core
Standard therapeutic approaches to acid peptic disorders have dealt with neutralizing or inhibiting aggressive factors and/or bolstering defensive factors.
WR Yacoub +3 more
doaj +1 more source
Oesophageal pH monitoring is an important component of preoperative workup for anti‐reflux surgery. This single‐centre cost–utility analysis found that wireless pH monitoring was associated with lower expected healthcare costs and higher QALYs, supporting it as a potentially cost‐effective alternative.
Du H. Phan +3 more
wiley +1 more source
In this randomized, double‐blind trial in Mexican adults with erosive oesophagitis, tegoprazan did not significantly improve the primary 4‐week ITT healing endpoint versus pantoprazole (88.9% vs. 79.4%; p = 0.33), but produced faster symptom improvement. Encouraging per‐protocol and severe‐oesophagitis findings warrant confirmation.
José M. Remes‐Troche +9 more
wiley +1 more source
Review – H. pylori and non-malignant diseases [PDF]
The article considers the role of Helicobacter pylori (H. pylori) in the formation and progression of non-malignant diseases of the upper gastrointestinal tract and reviews the results of studies published in the period from April 2023 to May 2024.
D. Bordin +3 more
doaj +1 more source
Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman +3 more
wiley +1 more source
The Value of Alarm Features in Identifying Organic Causes of Dyspepsia
The unaided clinical diagnosis of dyspepsia is of limited value in separating functional dyspepsia from clinically relevant organic causes of dyspepsia (gastric and esophageal malignancies, peptic ulcer disease and complicated esophagitis).
Lone Galmstrup Madsen, Peter Bytzer
doaj +1 more source
ABSTRACT Zastaprazan, a potassium‐competitive acid blocker, has been developed as an orally disintegrating tablet (ODT) to improve administration flexibility. This study evaluated the pharmacokinetics and safety of a single 20 mg dose of Zastaprazan ODT administered with or without water compared with the conventional tablet in healthy volunteers.
Hyung‐Gun Kim +4 more
wiley +1 more source
Sucralfate prevents experimental peptic esophagitis in rabbits
Sucralfate was tested in a rabbit model for its ability to prevent experimental esophagitis. Esophagitis was assessed by gross appearance and microscopic examination by an uninformed observer. In addition, the permeability of the esophagus to a number of
Johnson, Lawrence F. +3 more
core +1 more source

