Results 31 to 40 of about 33,298 (174)

Routine Preoperative Oesophagogastroduodenoscopy Before Roux‐En‐Y Gastric Bypass: A Retrospective Cohort Analysis From Queensland, Australia

open access: yesANZ Journal of Surgery, EarlyView.
Impact of routine POOGD with routine biopsies on surgical management in 423 patients undergoing RYGB. ABSTRACT Introduction The role of routine preoperative oesophagogastroduodenoscopy (POOGD) with routine biopsies prior to Roux‐en‐Y gastric bypass (RYGB) remains controversial.
Shahab Valizadehzare, Michael Hatzifotis
wiley   +1 more source

Helicobacter pylori and the management of gastro-oesophageal reflux disease [PDF]

open access: yes, 2005
This thesis is centred on the current controversy and possible links between H. pylori and GORD and whether the infection should be eradicated in those requiring long PPIs.
Raghunath, Anathakrishnapuram Srinivasan
core  

Lack of Effect of H2-Receptor Antagonists and Antacids on the Gastric and Duodenal Gastrin-, Somatostatin- and Serotonin-Producing Cells in Patients with Acid Peptic Disorders

open access: yesCanadian Journal of Gastroenterology, 1996
Standard therapeutic approaches to acid peptic disorders have dealt with neutralizing or inhibiting aggressive factors and/or bolstering defensive factors.
WR Yacoub   +3 more
doaj   +1 more source

Cost–Utility Analysis of Wireless Versus Catheter‐Based Oesophageal pH Monitoring in the Pre‐Operative Assessment of Anti‐Reflux Surgery: A Decision‐Analytic Model

open access: yesANZ Journal of Surgery, EarlyView.
Oesophageal pH monitoring is an important component of preoperative workup for anti‐reflux surgery. This single‐centre cost–utility analysis found that wireless pH monitoring was associated with lower expected healthcare costs and higher QALYs, supporting it as a potentially cost‐effective alternative.
Du H. Phan   +3 more
wiley   +1 more source

The TOP‐GERD Trial: Comparative Efficacy of Tegoprazan Versus Pantoprazole in the Treatment of Erosive Oesophagitis in a Non‐Asian Population

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In this randomized, double‐blind trial in Mexican adults with erosive oesophagitis, tegoprazan did not significantly improve the primary 4‐week ITT healing endpoint versus pantoprazole (88.9% vs. 79.4%; p = 0.33), but produced faster symptom improvement. Encouraging per‐protocol and severe‐oesophagitis findings warrant confirmation.
José M. Remes‐Troche   +9 more
wiley   +1 more source

Review – H. pylori and non-malignant diseases [PDF]

open access: yesMicrobiota in Health and Disease
The article considers the role of Helicobacter pylori (H. pylori) in the formation and progression of non-malignant diseases of the upper gastrointestinal tract and reviews the results of studies published in the period from April 2023 to May 2024.
D. Bordin   +3 more
doaj   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman   +3 more
wiley   +1 more source

The Value of Alarm Features in Identifying Organic Causes of Dyspepsia

open access: yesCanadian Journal of Gastroenterology, 2000
The unaided clinical diagnosis of dyspepsia is of limited value in separating functional dyspepsia from clinically relevant organic causes of dyspepsia (gastric and esophageal malignancies, peptic ulcer disease and complicated esophagitis).
Lone Galmstrup Madsen, Peter Bytzer
doaj   +1 more source

Comparative Pharmacokinetics and Safety of Orally Disintegrating and Conventional Tablet Formulations of Zastaprazan in Healthy Subjects

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 6, December 2026.
ABSTRACT Zastaprazan, a potassium‐competitive acid blocker, has been developed as an orally disintegrating tablet (ODT) to improve administration flexibility. This study evaluated the pharmacokinetics and safety of a single 20 mg dose of Zastaprazan ODT administered with or without water compared with the conventional tablet in healthy volunteers.
Hyung‐Gun Kim   +4 more
wiley   +1 more source

Sucralfate prevents experimental peptic esophagitis in rabbits

open access: yes, 1985
Sucralfate was tested in a rabbit model for its ability to prevent experimental esophagitis. Esophagitis was assessed by gross appearance and microscopic examination by an uninformed observer. In addition, the permeability of the esophagus to a number of
Johnson, Lawrence F.   +3 more
core   +1 more source

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