Results 191 to 200 of about 46,071 (297)

Breaking the Bottleneck in Limit of Detection of Surface Refractive Index Sensing by Harnessing Meta‐Waveguide Microring Resonators

open access: yesAdvanced Science, EarlyView.
Mode splitting in meta‐waveguide microring resonators (MWMRs) effectively suppresses baseline drift and measurement noise while maintaining high refractive‐index sensitivity. This reflection‐induced mode splitting strategy enables quantitative detection of ultra‐weak surface perturbations and establishes MWMRs as a robust, drift‐immune platform for ...
Wanxin Li   +8 more
wiley   +1 more source

Discovery of a Potent Fluorescence Polarization Probe for Identifying USP1 Allosteric Inhibitors

open access: yesAdvanced Science, EarlyView.
This study presents the first ubiquitin‐specific protease 1 (USP1) allosteric fluoroprobe and fluorescence polarization assay, enabling the differentiation of allosteric and catalytic site inhibitors. Further, a novel class of tetrahydroisoquinoline‐based USP1 inhibitors is designed, with compound 14a (USP1 IC50 = 29.9 nM) showing strong selectivity ...
Jiawei Cheng   +12 more
wiley   +1 more source

Prevalence and age-related trends of refractive errors in Mexican outpatients: a cross-sectional study. [PDF]

open access: yesFront Public Health
García-Gil A   +7 more
europepmc   +1 more source

Laser‐Induced Periodic Phase‐Transition of 2D‐MoTe2 Nanograting Template for Frequency‐Shift Digital‐SERS Immunoassay of Autoimmune Disease

open access: yesAdvanced Science, EarlyView.
A protocol of fs‐laser‐induced periodic phase‐transition of 2D‐MoTe2 template, inducing AuNPs@1T’‐MoTe2 nanograting, is developed. The labeled AuNPs@1T’‐MoTe2 substrate conjugated with specialized immunoglobulin G demonstrates an unexpectedly high discrimination accuracy close to unity for serological diagnosis of rheumatoid arthritis by frequency ...
Yao Yao   +9 more
wiley   +1 more source

Multi‐Channel Electrically Tunable Varifocal Metalens With Compact Multilayer Polarization‐Dependent Metasurfaces and Liquid Crystals

open access: yesAdvanced Science, EarlyView.
A compact eight‐channel electrically tunable varifocal metalens with three single‐layer polarization‐multiplexed bi‐focal metalens and three LC cells. The total thickness of the device is ∼6 mm, while the focal lengths can be switched among eight values (3.6, 4.2, 4.5, 4.9, 6.2, 6.9, 8.4, and 9.6 mm). ABSTRACT As an essential module of optical systems,
Zhiyao Ma   +11 more
wiley   +1 more source

A Flexible Metamaterial Absorber via Loss Engineering for Large‐Area Ultra‐Broadband Infrared Extinction

open access: yesAdvanced Science, EarlyView.
Designed and demonstrated a flexible metamaterial absorber via loss engineering for large‐area ultra‐broadband infrared extinction, providing a new method for miniaturization of absorbers and flexible optical devices. ABSTRACT The advancement of compact and wearable optical systems is critically limited by the lack of high‐performance, integrable ...
Zhe Wu   +11 more
wiley   +1 more source

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