Results 21 to 30 of about 32,366 (210)
Current Opinion in Oncology, 2013 Concept of refractory coeliac disease (RCD) emerged in the past decade and refers to persistence of malnutrition and intestinal villous atrophy for more than 1 year strict gluten-free diet in coeliac patients. Diagnosis of this condition remains difficult and conditions treatment and follow-up.RCD has been subdivided into two subgroups according to the
Georgia, Malamut, Christophe, Cellier
openaire +5 more sources
Dependency of calcium alternans on Ryanodine Receptor Refractoriness [PDF]
, 2013 Background Rapid pacing rates induce alternations in the cytosolic calcium concentration caused by fluctuations in calcium rele However, the relationship between calcium alternans and refractoriness of the SR calcium release channel (RyR2) Methodology/
Echebarría Domínguez, Blas +32 more
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Global Journal of Transfusion Medicine, 2019 Platelet transfusion support is extensively required for hemato-oncology patients who are multiply transfused. Platelet refractoriness can represent a significant clinical condition that complicates the platelet transfusion support in such patients.
B Sunil Rajadhyaksha +2 more
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Frontiers in Endocrinology, 2020 BackgroundA growth hormone (GH) stimulation test is the recommended method for evaluating GH levels in children with possible GH deficiency (GHD). However, serial measurements of nocturnal spontaneous GH secretion are also performed.
Otto Lennartsson +3 more
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Вопросы современной педиатрии, 2016 Background. Blocking of B lymphocytes producing autoantibodies in systemic lupus erythematosus (SLE) may be an effective strategy for pathogenetic treatment, including in children.
Ekaterina I. Alexeeva +8 more
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Clinical Case Reports, 2019 In a minority of relapsed myeloma, patient's disease may spread into extramedullary sites, associated with high degrees of heterogeneity. The breadth of myeloma therapeutic armamentarium allows clinicians to manage its heterogeneous presentation ...
Uros Markovic +8 more
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Bortezomib Combination Therapy of Relapsed and Refractory Acute Lymphoblastic Leukemia in Children
Клиническая онкогематология, 2017 Background & Aims. Despite significant success in the treatment of acute lymphoblastic leukemia (ALL) in children, relapses and drug resistance to the standard therapy remain the main cause of treatment failure.
Natal’ya Andreevna Batmanova +5 more
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IL-10 and IL-6/IL-10 as predictive biomarkers for treatment response in non-infectious uveitis
Frontiers in ImmunologyUveitis, a group of heterogeneous diseases causing ocular inflammation, is a major contributor to vision loss globally. While systemic corticosteroids (CS) are the mainstay treatment, identifying CS-refractory patients remains a significant challenge ...
Rodrigo A. Valenzuela +14 more
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Current advances in the treatment of gastroesophageal reflux disease: a focus on esophageal protection [PDF]
Терапевтический архив, 2019 Gastroesophageal reflux disease (GERD) is characterized by high morbidity and a significant decrease in the quality of life of patients, and is a major risk factor for esophageal adenocarcinoma. Nowadays, antisecretory therapy with proton pump inhibitors
I V Maev +3 more
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A Mathematical Model to Characterize the Role of Light Adaptation in Mammalian Circadian Clock
Frontiers in Molecular Biosciences, 2021 In response to a light stimulus, the mammalian circadian clock first dramatically increases the expression of Per1 mRNA, and then drops to a baseline even when light persists.
Yuzeng Shi, Yu Liu, Ling Yang, Jie Yan
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