Results 41 to 50 of about 32,366 (210)

Chronic migraine: treatability, refractoriness, pseudo-refractoriness [PDF]

open access: yesThe Journal of Headache and Pain, 2015
Chronic migraine (CM), a highly disabling condition affecting 2-3% of the general population, represents a difficult-to-treat disorder for its unclear pathophysiology, complex comorbidities, and disappointing response to available pharmacological treatments[1]. High quality evidence (≥2 RCTs) recommends the prophylactic use of onabotulinum toxin A (155-
Barbanti, Piero   +4 more
openaire   +2 more sources

Efficacy of rechallenge transcatheter arterial chemoembolization after lenvatinib treatment for advanced hepatocellular carcinoma

open access: yesJGH Open, 2022
Background and Aim We evaluated the efficacy of rechallenge transcatheter arterial chemoembolization (TACE) after lenvatinib (LEN) treatment in patients with previous TACE failure/refractoriness. Methods We enrolled 63 consecutive patients with a history
Sawako Uchida‐Kobayashi   +18 more
doaj   +1 more source

Dismal outcome of refractory or relapsing patients with myelodysplasia‐related acute myeloid leukemia partially alleviated by intensive chemotherapy

open access: yesCancer Medicine
Background Acute myeloid leukemia (AML) with myelodysplasia‐related characteristics is a heterogeneous subset of AML that has been challenged throughout the history of myeloid malignancies classifications, considered to have similar outcomes as ...
Harmony Leroy   +18 more
doaj   +1 more source

Genetics of refractoriness to Plasmodium falciparum in the mosquito Anopheles stephensi [PDF]

open access: yes, 1998
We previously selected a line of the malaria vector mosquito Anopheles stephensi refractory (resistant) to the human malaria parasite Plasmodium falciparum, using in vitro infections with P. falciparum gametocytes.
Vegte-Bolmer, Marga G. van de   +3 more
core   +1 more source

Prevalence of platelet reactive antibodies in patient′s refractory to platelet transfusions

open access: yesAsian Journal of Transfusion Science, 2014
Introduction & Aims: Though platelet transfusions have greatly reduced the incidence of major haemorrhagic complications associated with the management of haematological and oncological disorders, refractoriness to infused platelets becomes a major ...
Nitin Agarwal   +3 more
doaj   +1 more source

Prediction of transarterial chemoembolization refractoriness in patients with hepatocellular carcinoma using imaging features of gadoxetic acid-enhanced magnetic resonance imaging

open access: yes, 2021
Background: Repeated transarterial chemoembolization (TACE) can be associated with loss of its efficacy and subsequent tumor progression. Purpose: To identify features of gadoxetic acid-enhanced magnetic resonance imaging (MRI) associated with TACE ...
심주현   +6 more
core   +1 more source

Modeling Refractoriness for Stochastically Driven Single Neurons

open access: yes, 2008
A description of the sequence of interspike intervals and of the subsequent firing times for single neurons is performed by means of an instantaneous return process in the presence of refractoriness.
V. GIORNO   +3 more
core   +1 more source

RHEUMATOID ARTHRITIS: THE PROBLEMS OF REMISSION AND THERAPY RESISTANCE

open access: yesНаучно-практическая ревматология, 2018
Rheumatoid arthritis (RA) is an immunoinflammatory (autoimmune) rheumatic disease of unknown etiology, which is characterized by chronic erosive arthritis and systemic visceral organ damage that results in early disability and shorter patient survival ...
E. L. Nasonov   +2 more
doaj   +1 more source

Development and Validation of a Predictive Model for Early Refractoriness of Transarterial Chemoembolization in Patients With Hepatocellular Carcinoma

open access: yesFrontiers in Molecular Biosciences, 2021
Objectives: To develop and validate a predictive model for early refractoriness of transarterial chemoembolization (TACE) in patients with hepatocellular carcinoma (HCC).Methods: In this multicenter retrospective study, a total of 204 consecutive ...
Tian-Cheng Wang   +4 more
doaj   +1 more source

Vasopressin-elicited refractoriness of the response to vasopressin in toad urinary bladder

open access: yes, 1981
Incubation of the urinary bladder of Bufo marinus with high concentrations of vasopressin produces refractoriness to subsequent stimulation of water permeability by low concentrations of vasopressin.
J. S. Handler, A. S. Preston
core   +1 more source

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