Results 41 to 50 of about 836,249 (298)
Ruxolitinib for Glucocorticoid-Refractory Acute Graft-versus-Host Disease.
New England Journal of Medicine, 2020 BACKGROUND Acute graft-versus-host disease (GVHD) remains a major limitation of allogeneic stem-cell transplantation; not all patients have a response to standard glucocorticoid treatment.
R. Zeiser +13 more
semanticscholar +1 more source
Maximizing the Utility of Transcriptomics Data in Inflammatory Skin Diseases
Frontiers in Immunology, 2021 Inflammatory skin diseases are induced by disorders of the host defense system of the skin, which is composed of a barrier, innate and acquired immunity, as well as the cutaneous microbiome.
Jingni Wu +5 more
doaj +1 more source
Clinical characteristics of refractory COVID-19 pneumonia in Wuhan, China
Clinical Infectious Diseases, 2020 Background Since December 2019, novel coronavirus (SARS-CoV-2)-infected pneumonia (COVID-19) occurred in Wuhan, and rapidly spread throughout China. This study aimed to clarify the characteristics of patients with refractory COVID-19.
Pingzheng Mo +18 more
semanticscholar +1 more source
CellsThe growing global elderly population underscores the escalating importance of anti-aging interventions to combat age-related diseases and extend both health span and lifespan.
An Yu, Changguo Ma, Min Hu
doaj +1 more source
Materials and Energy Balance of E-Waste Smelting—An Industrial Case Study in China
Metals, 2021 The application of Nerin Recycling Technologies (NRT) in electronic waste (E-waste) smelting was introduced in this study, and the material and energy balance was calculated based on the practical data with the METSIM software (METSIM International, USA).
Fengchun Ye, Zhihong Liu, Longgong Xia
doaj +1 more source
Results of the Childhood Cancer and Leukaemia Group's United Kingdom Relapsed Wilms Tumour Trial
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background The United Kingdom relapsed Wilms tumour (UKW‐R) trial aimed to improve the historically low survival rates after relapse of Wilms tumour (WT) through a prospective national risk‐stratified protocol. The trial also evaluated efficacy and toxicity of high‐dose melphalan.
Sucheta J. Vaidya +10 more
wiley +1 more source
Durable Remissions with Ivosidenib in IDH1‐Mutated Relapsed or Refractory AML
New England Journal of Medicine, 2018 Background Mutations in the gene encoding isocitrate dehydrogenase 1 (IDH1) occur in 6 to 10% of patients with acute myeloid leukemia (AML). Ivosidenib (AG‐120) is an oral, targeted, small‐molecule inhibitor of mutant IDH1. Methods We conducted a phase 1
C. Dinardo +39 more
semanticscholar +1 more source
The Lancet, 2020 BACKGROUND Among patients with out-of-hospital cardiac arrest (OHCA) and ventricular fibrillation, more than half present with refractory ventricular fibrillation unresponsive to initial standard advanced cardiac life support (ACLS) treatment. We did the
D. Yannopoulos +17 more
semanticscholar +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Journal of Materials Research and TechnologyThis study examines the hot deformation behavior of Mo-14Re alloy at various true strains (15%, 35%, 65%) and strain rates (0.01 s−1, 10 s−1) at a temperature of 1400K. The findings indicate that dynamic recovery (DRV) and dynamic recrystallization (DRX)
Yanchao Li +8 more
doaj +1 more source