Results 141 to 150 of about 1,855,208 (237)

Validation of the TruBlue Light Laser for Laryngeal Somatosensory and Perturbation Testing

open access: yesThe Laryngoscope, Volume 136, Issue 9, Page 3841-3848, September 2026.
This study validates a blue light laser method for assessing laryngeal somatosensory function by measuring perceptual thresholds, reflexive responses, discrimination acuity, and vocal perturbations in healthy adults. Results demonstrate that the method provides precise, reliable stimulation and yields quantifiable sensory and acoustic responses ...
Adrianna C. Shembel   +6 more
wiley   +1 more source

Patient satisfaction with the management of refractory and unexplained chronic cough in Canada: Results from a national survey.

open access: yesPLoS ONE
BackgroundChronic cough (persisting for ≥8 weeks) is a common disorder affecting approximately 5 to 10% of adults worldwide that is sometimes refractory to treatment (refractory chronic cough [RCC]) or has no identifiable cause (unexplained chronic cough
Sana Khan   +6 more
doaj   +1 more source

Is Aripiprazole an Effective Adjunct to Reduce Metabolic Adverse Effects Caused by Clozapine in Patients With Schizophrenia—A Systematic Review

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.
Adjunctive aripiprazole may provide modest improvements in lipid parameters and body weight in clozapine‐treated patients with schizophrenia, but evidence for glucose and waist circumference outcomes remains limited. Larger, long‐term randomized controlled trials are needed.
Avtaar Singh, Soban Sadiq
wiley   +1 more source

Drugs Targeting Cough Receptors: New Therapeutic Options in Refractory or Unexplained Chronic Cough

open access: yes
International audienceRefractory chronic cough is a disabling disease with very limited therapeutic options. A better understanding of cough pathophysiology has led to the development of emerging drugs targeting cough receptors.
Grassin-Delyle, Stanislas   +2 more
core   +1 more source

Three Adult Cases of ADHD With Comorbid Tic Symptoms Successfully Treated With Guanfacine Monotherapy

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.
Guanfacine extended‐release can be an effective monotherapy for adults with ADHD and comorbid tic disorders. A low dose of guanfacine was sufficient to produce a rapid improvement in tic symptoms in each patient before improving ADHD symptoms. ABSTRACT Tic disorders typically begin in childhood and often improve by adulthood, but some individuals ...
Koji Tada   +3 more
wiley   +1 more source

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

open access: yesPrecision Medical Sciences, Volume 15, Issue 3, Page 206-226, September 2026.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source

Isolated Central Nervous System Tuberculosis‐Associated Immune Reconstitution Inflammatory Syndrome—Case Report and Literature Review

open access: yesRespirology Case Reports, Volume 14, Issue 9, September 2026.
Disseminated tuberculosis in an immunocompetent young male initially improved with anti‐tuberculosis therapy. Early treatment was complicated by drug‐induced liver injury and paradoxical isolated CNS‐TB‐IRIS with new intracranial lesions despite systemic disease regression.
Mithen Ravisankar   +6 more
wiley   +1 more source

Cough-hypersensitivity Syndrome-A New Paradigm in the Evaluation of Chronic Refractory Cough and Its Novel Therapeutic Horizons-A Review

open access: yes
Chronic cough is defined as a persistent cough, lasting beyond 8 weeks, poses a global health challenge, impacting a substantial portion of the world’s population.
Khan, Dawlat   +7 more
core   +1 more source

The Changing Landscape of Hantavirus Infections: A Narrative Review of Epidemiology, Pathogenesis, and Countermeasures

open access: yesReviews in Medical Virology, Volume 36, Issue 5, September 2026.
ABSTRACT Hantaviruses are emerging zoonotic pathogens of increasing global public health significance. Their epidemiological landscape is rapidly changing due to ecological disruption, climate variability, urbanisation, and evolving human–animal interfaces.
Francesco De Maria   +5 more
wiley   +1 more source

Peripheral κ opioid receptor in pain and inflammation: From molecular signalling and gene expression to drug discovery

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 17, Page 5157-5189, September 2026.
The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan   +3 more
wiley   +1 more source

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