Results 141 to 150 of about 17,784 (227)

The Therapeutic Landscape in Chronic Cough

In recent years, there has been a substantial increase in the development of antitussive therapies and the first new therapy, gefapixant has been licenced in Europe.
Smith, Jaclyn A; id_orcid
core   +1 more source

Clarifying Terminology in Chronic Cough: The Evolving Role of Cough Hypersensitivity Syndrome

The Clinical Respiratory Journal, Volume 20, Issue 6, June 2026.
This review clarifies the definitions and relationships among ICC, UCC, and RCC, and introduces cough hypersensitivity syndrome (CHS) as an important pathophysiological framework for understanding chronic cough. Within this framework, CHS provides a mechanism‐based perspective that may complement existing terminology, guide future research, and improve
Zihang Wang, Yaxing Zhou, Yingchun Ren, Jiaying Yuan, Tongyangzi Zhang, Shengyuan Wang, Wanzhen Li, Li Yu, Xianghuai Xu   +8 more
wiley   +1 more source

A randomized, double-blinded, placebo-controlled clinical trial of duloxetine hydrochloride enteric-coated tablets in the treatment of refractory chronic cough. [PDF]

BMC Pulm Med, 2023
Wang S, Li S, Wu H, Zhang T, Chen Y, Zhu Y, Wen S, Shi C, Yu L, Xu X.   +9 more
europepmc   +1 more source

Acalabrutinib in Chronic Lymphocytic Leukemia: Pharmacology and Emerging Clinical Perspectives

European Journal of Haematology, Volume 116, Issue 6, Page 759-770, June 2026.
ABSTRACT Acalabrutinib, a second‐generation Bruton's tyrosine kinase inhibitor (BTKi), is characterized by enhanced specificity and selectivity for BTK with minimal off‐target effects, offering a significant evolution in the treatment of chronic lymphocytic leukemia (CLL). Its mechanism of action, a covalent binding to Cys481 within the BTK active site,
Gianluca Gaidano, Romano Danesi
wiley   +1 more source

Efficacy and Safety of Eliapixant in Refractory Chronic Cough: The Randomized, Placebo-Controlled Phase 2b PAGANINI Study. [PDF]

Lung, 2023
Dicpinigaitis PV, Morice AH, Smith JA, Sher MR, Vaezi M, Guilleminault L, Niimi A, Gude K, Krahn U, Saarinen R, Pires PV, Wosnitza M, McGarvey L, PAGANINI Investigators.   +13 more
europepmc   +1 more source

The clinical approach to chronic cough

Chronic cough remains a significant clinical challenge, affecting approximately 10% of the population and leading to significant impairment in psychological, social and physical quality of life.
Birring, Surinder S, Hassan, Wafa, Satia, Imran, McGarvey, Lorcan   +3 more
core   +1 more source

Bridging Rare to Common Diseases: Precision Medicine and the Transforming Landscape of Pediatric Allergy and Immunology

Pediatric Allergy and Immunology, Volume 37, Issue 6, June 2026.
This graphical abstract illustrates the conceptual framework linking rare and common diseases in pediatric allergy and immunology through precision medicine. On the left, rare conditions such as inborn errors of immunity and primary atopic disorders represent well‐defined monogenic models that reveal fundamental mechanisms of immune dysregulation.
Riccardo Castagnoli, Martina Votto, Ivan Taietti, Maria Isabel Delgado‐Dolset, Rubén Fernández‐Santamaría, Martha Jimenez Freites, Mattia Giovannini, Mark Kačar, Aspasia Karavelia, Janice Layhadi, Urszula Radzikowska, Cezmi A. Akdis, Mubeccel Akdis, Marketa Bloomfield, Francesco Cinetto, Antoine Deschildre, Jonathan Hourihane, Susanne Lau, Antonio Nieto‐Garcia, Ismail Ogulur, Liam O'Mahony, Mohamed Shamji, Milena Sokolowska, Maria Jose Torres, Sophia Tsabouri, Philippe Eigenmann, on behalf of the EAACI‐Clemens von Pirquet Foundation   +26 more
wiley   +1 more source

Behavioural cough suppression therapy: a twisting journey to frontline therapy for refractory chronic cough. [PDF]

ERJ Open Res
Sundar KM, Jetté ME.
europepmc   +1 more source

Randomised trial of the P2X₃ receptor antagonist sivopixant for refractory chronic cough. [PDF]

Eur Respir J, 2022
Niimi A, Saito J, Kamei T, Shinkai M, Ishihara H, Machida M, Miyazaki S.   +6 more
europepmc   +1 more source

Bronchoscopic evaluation and final diagnosis in patients with chronic non productive cough with normal Chest X ray

, 2010
When a proper detailed history, clinical examination, chest X ray and sputum analysis does not yield a definite diagnosis for the cause of chronic cough, bronchoscopy is indicated.
Anupama N, Vishnu, SM, Vishnu SM, Pradeep, NP, Pradeep NP, Anupama, N, Mithra, PP, Mithra PP   +7 more
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