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Chest, 2022 Chronic refractory cough (CRC) increasingly is recognised as a distinct clinical entity; cough that persists despite addressing potential aggravating factors (eg, asthma, acid reflux, angiotensin-converting enzyme medication).1 CRC is associated with ...
Peter S.P. Cho, Richard D. Turner
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Chronic Refractory Cough: Objective Improvement With Aerodynamic-Focused
Journal of Voice, 2021Previous investigations have reported that a chronic cough that is refractory to medical therapies improves with behavioral therapies. However, the treatment parameters that may account for improvement in cough symptoms have not yet been objectively documented. The purpose of this study was to document changes in chronic refractory cough using a breath
Brianna K Crawley +2 more
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Chronic Refractory Cough: A Case Study
Perspectives of the ASHA Special Interest Groups, 2017 This paper presents a successful behavioral case study in treatment of chronic refractory cough in a 60-year-old adult female. The efficacy for speech-language pathology treating chronic cough is discussed along with description of treatment regime. Discussion focuses on therapy approaches used and the patient's report of changes in quality of life and
Anna Maria Siciliano
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Structural and Functional Correlates of Higher Cortical Brain Regions in Chronic Refractory Cough
Chest, 2022 Background: Chronic refractory cough significantly impairs the psychological and social aspects of quality of life. Loss of inhibitory control is suggested as a potential central neurobiological mechanism underlying chronic refractory cough.
Eun Namgung +2 more
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Lancet, The, 2022 Background: Gefapixant is an oral P2X3 receptor antagonist that has previously shown efficacy and safety in refractory chronic cough and unexplained chronic cough.
Surinder S Birring +2 more
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Management of chronic refractory cough
BMJ, 2015Chronic refractory cough (CRC) is defined as a cough that persists despite guideline based treatment. It is seen in 20-46% of patients presenting to specialist cough clinics and it has a substantial impact on quality of life and healthcare utilization. Several terms have been used to describe this condition, including the recently introduced term cough
Gibson, Peter G., Vertigan, Anne E.
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Treatment of Chronic, Refractory Cough with Baclofen
Respiration, 1998Chronic, nonproductive cough may result from enhanced sensitivity of the cough reflex. Often, this debilitating symptom is refractory to standard antitussive therapy. Baclofen, an agonist of γ-aminobutyric acid (GABA), has been shown, in animals, to have antitussive activity via a central mechanism.
P V, Dicpinigaitis, K, Rauf
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The Efficacy of Bradanicline in Refractory Chronic Cough
Airway pharmacology and treatment, 2020Background: Several clinical studies have implicated nicotine in reducing cough reflex sensitivity in both healthy smoking and non-smoking subjects. Bradanicline, a highly selective α7 nicotinic acetylcholine receptor (nAChR) agonist, may therefore be effective for refractory chronic cough (RCC), possibly through sensory gating in the central nervous ...
Yoshihiro Kanemitsu +6 more
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Patient-Reported Qualitative Analysis of Chronic Refractory Cough
American Journal of Speech-Language Pathology, 2022Purpose: Chronic cough has been shown to be associated with adverse effects on quality of life. There is a paucity of research characterizing quality-of-life factors associated with chronic refractory cough (CRC), a cough persisting > 8 weeks despite evaluation and treatment of possible etiologies.
Miranda L. Wright +3 more
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Lung
Refractory chronic cough (RCC) significantly impairs patient quality of life and poses a major challenge in clinical management. However, little is known about the healthcare resource utilization (HRU) of patients with RCC.The goal of our study is to describe the HRU and associated costs of RCC patients and those with non-refractory chronic cough (non ...
Guilleminault, Laurent +7 more
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Refractory chronic cough (RCC) significantly impairs patient quality of life and poses a major challenge in clinical management. However, little is known about the healthcare resource utilization (HRU) of patients with RCC.The goal of our study is to describe the HRU and associated costs of RCC patients and those with non-refractory chronic cough (non ...
Guilleminault, Laurent +7 more
openaire +3 more sources