Results 101 to 110 of about 59,639 (336)

New-onset refractory status epilepticus (NORSE) in paediatric patients: causes, characteristics and outcomes

BMJ Neurology Open, 2022
Background New-onset refractory status epilepticus (NORSE) refers to patients without a previous history of seizures who have refractory status epilepticus for at least 72 hours without an identified aetiology. Despite the severe neurological sequelae of
Francisco Bruno, Paulo Carvalho, Ana Luiza Tainski de Azevedo, Cristian Tedesco Tonial, Gabriela Rupp Hanzen Andrades, Caroline Abud Drumond Costa, Francielly Crestani, Alessandra Rodrigues Lessa, Guilherme Eckert, Jeferson Piva, Pedro Celiny Ramos Garcia   +10 more
doaj   +1 more source

Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects [PDF]

, 2012
Temporal lobe epilepsy is a common, chronic neurological disorder characterized by recurrent spontaneous seizures. MicroRNAs (miRNAs) are small, noncoding RNAs that regulate post-transcriptional expression of protein-coding mRNAs, which may have key ...
A Pavlowsky, A Pitkänen, A Pitkänen, A Vezzani, B Lee, BM Murphy, C Brandt, CH Kim, CM O'Tuathaigh, Colm O'Tuathaigh, David C Henshall, DH Bhatt, Donncha F O'Brien, DP Bartel, DP Wermeling, E Aronica, EM Jimenez-Mateos, EM Jimenez-Mateos, EM Jimenez-Mateos, Eva M Jimenez-Mateos, FV Karginov, G Mouri, G Sierra-Paredes, Genshin Mouri, GM Schratt, I Ballesteros-Yáñez, J DeFelipe, J Elmén, J Gao, J Krützfeldt, J Krützfeldt, J Nairismägi, J Noguchi, J Tao, J Wetherington, JA Saugstad, Javier DeFelipe, JE Cavazos, JO McNamara, John L Waddington, K Hu, Katsuhiro Tanaka, KL Stark, L Peters, LH Zeng, M Christensen, M Lagos-Quintana, M Matsuzaki, M Müller, M Segal, Michael A Farrell, N Rensing, Norman Delanty, P Merino-Serrais, P Penzes, Paula Merino-Serrais, Q Zhou, R Meller, Raymond L Stallings, Ronán M Conroy, Ross C McKiernan, S Halpain, S Shinoda, SM Eacker, Suzanne Prenter, T Araki, T Engel, T Engel, T Saneyoshi, Takanori Sano, Tobias Engel, UV Nägerl, V Ambros, Y Meng, YJ Song   +74 more
core   +3 more sources

Functional outcome of prolonged refractory status epilepticus [PDF]

Critical Care, 2015
Abstract Introduction To characterize etiology, clinical course and outcomes of patients in prolonged refractory status epilepticus (PRSE) and looking for prognostic factors. Methods Retrospective study conducted in patients hospitalized from January 1, 2001 to December 31 ...
Lai, Alexandre, Outin, Hervé D., Jabot, Julien, Mégarbane, Bruno, Gaudry, Stéphane, Coudroy, Rémi, Louis, Guillaume, Schneider, Francis, Barbarot, Nicolas, Roch, Antoine, Lerolle, Nicolas, Luis, David, Fourrier, François, Renault, Anne, Argaud, Laurent, Sharshar, Tarek, Gibot, Sébastien, Bollaert, Pierre-Edouard   +17 more
openaire   +3 more sources

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

Epilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola, Marica Rubino, Antonella Riva, Pasquale Striano   +3 more
wiley   +1 more source

Responsive neuro stimulation [RNS] system for management of refractory status epilepticus

Interdisciplinary Neurosurgery, 2021
Super refractory Status epilepticus is traditionally associated with high morbidity and mortality. We present a case of focal super-refractory status epilepticus who had the Responsive Neuro Simulation System (RNS) implanted emergently.
Christina Graley, Rachel Aubert, Soundarya N. Gowda, Kathryn Holloway   +3 more
doaj  

Intensive care management of status epilepticus

Journal of Neuroanaesthesiology and Critical Care, 2016
Status epilepticus (SE) is a life-threatening neurological emergency that requires prompt diagnosis and treatment. SE may be classified into convulsive and non-convulsive types, based on the presence of rhythmic jerking of the extremities.
Nidhi Gupta
doaj   +1 more source

Treatment Options in the Management of Status Epilepticus [PDF]

, 2018
Opinion statement: Status epilepticus treatment involves the use of several pharmacologic compounds, which are conceptually divided into three successive and additional lines of action.
Rossetti, Andrea
core  

DNM1 encephalopathy: A new disease of vesicle fission. [PDF]

, 2017
ObjectiveTo evaluate the phenotypic spectrum caused by mutations in dynamin 1 (DNM1), encoding the presynaptic protein DNM1, and to investigate possible genotype-phenotype correlations and predicted functional consequences based on structural modeling ...
Campbell, Colleen A, Cervenka, Mackenzie C, Cilio, Maria R, Cohen, Julie S, Dlugos, Dennis J, Epi4K Consortium, EuroEPINOMICS-RES NLES Working Group, Fatemi, Ali, Helbig, Ingo, Helbig, Katherine L, Hernandez-Hernandez, Laura, Hollingsworth, Georgie, Huether, Robert, Joshi, Charuta N, Kaplan, Richard A, Kirsch, Heidi, Kolbe, Diana L, Lawson, John A, Littlejohn, Rebecca, Lourenço, Charles, Maher, Bridget, McClellan, Rebecca, McLean, Scott D, Muhle, Hiltrud, Møller, Rikke S, Neubauer, Bernd A, Nunes, Mark E, Palmer, Elizabeth, Pena, Sérgio DJ, Pendziwiat, Manuela, Sagawa, Yoshimi, Sarco, Dean P, Scheffer, Ingrid E, Shinde, Deepali N, Sisodiya, Sanjay M, Slavotinek, Anne, Stephani, Ulrich, von Spiczak, Sarah, Yuen, Amy   +38 more
core   +2 more sources

Cardiac injury in refractory status epilepticus [PDF]

Epilepsia, 2012
SummaryPurpose:  We sought to describe the spectrum of cardiac injury in refractory status epilepticus (RSE).Methods:  We reviewed all patients with RSE between 1999 and 2011 at Mayo Clinic. RSE was defined as generalized convulsive or nonconvulsive status epilepticus (SE) that continued despite initial therapies.
Alejandro A. Rabinstein, Abhiram Prasad, Sara E. Hocker   +2 more
openaire   +3 more sources

First reported case of Human Parechovirus encephalitis in an adult patient complicated by Refractory Status Epilepticus

IDCases, 2019
Human Parechovirus (HPeV) infections are common amongst children, particularly neonates. However, data in adult cases are lacking. We report a unique case of HPeV meningoencephalitis in an adult complicated by Refractory Status Epilepticus (RSE ...
Timothy Chimunda, Rakhee Subramanian, Julie Smith, Andrew Mahony   +3 more
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