Results 81 to 90 of about 10,949 (215)

Super-Refractory Status Epilepticus: An Atypical Presentation and Case-Based Review

Archives of Epilepsy, 2015
Super-refractory status epilepticus is known to typically arise either from a distinct underlying cause or, in patients with no history of epilepsy, from no overt cause.
Chiazor Udochukwu ONYIA, Morenikeji A. KOMOLAFE, Ayo M. ADEBIYI, Olusegun OYEWOLE, Fola A. FAPONLE   +4 more
doaj   +1 more source

New-Onset Refractory Status Epilepticus Mimicking Herpes Virus Encephalitis

Case Reports in Neurology, 2013
New-onset refractory status epilepticus (NORSE) is a recently defined clinical entity that describes patients who present with status epilepticus of unclear etiology that is highly refractory to therapy.
Gianfranco Puoti, Andrea Elefante, Dario Saracino, Antonella Capasso, Roberto Cotrufo, Clara Belluomo Anello   +5 more
doaj   +1 more source

Long‐term prognosis of pharmacotherapy in newly diagnosed focal epilepsy patients and the predictive value of baseline seizure timing: A prospective cohort study

Epilepsia, EarlyView.
Abstract Objective Epilepsy is a highly heterogeneous neurological disorder with significant prognostic variability. Accurate long‐term outcome prediction remains a clinical challenge. We investigated pharmacotherapeutic prognosis and key predictors, particularly baseline seizure timing, to guide individualized treatment.
Lei Sun, Shouye Sun, Xinyue Zhang, Weihong Lin   +3 more
wiley   +1 more source

Emergency surgery for refractory status epilepticus

Indian Pediatrics, 2017
Management of refractory status epilepticus in children is extremely challenging.Two children with medically refractory status epilepticus, both of whom had lesional pathology on MRI and concordant data on EEG and PET scan.Emergency hemispherotomy performed in both patients.
Abhijeet, Botre, Vrajesh, Udani, Neelu, Desai, Spoorthy, Jagadish, Milind, Sankhe   +4 more
openaire   +2 more sources

Modeling temporal lobe epilepsy with hippocampal sclerosis in rats using the selective neurotoxin stable substance P‐saporin

Epilepsia, EarlyView.
On day 0 adult male and female rats were injected with Stable Substance P‐Saporin (SSP‐SAP) at 4 unilateral sites along the longitudinal axis of the dentate gyrus. Rats exhibited spontaneous electrographic and behavioral reactive seizures between days 4‐6. There was a progressive loss of CA1 and CA3 neurons and a progressive increase in astrocytes over
Srijal Gupta, Mitchell T. Kesler, Morris H. Scantlebury, Robert S. Sloviter, G. Campbell Teskey   +4 more
wiley   +1 more source

Epilepsy syndromes classification

Epilepsia Open, EarlyView.
Abstract Epilepsy syndromes are distinct electroclinical entities which have been recently defined by the International League Against Epilepsy Nosology and Definitions Task Force. Each syndrome is associated with “a characteristic cluster of clinical and EEG features, often supported by specific etiologic findings”.
Elaine C. Wirrell, Nicola Specchio, Rima Nabbout, Phillip L. Pearl, Kate Riney   +4 more
wiley   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Status Epilepticus Type, Etiology, and Treatment: One-year Data

Archives of Epilepsy
Objective: This study aimed to review the demographic characteristics, type, and etiology of status epilepticus (SE) cases followed in our hospital for a period of 1 year and to reveal the factors affecting the prognosis of the patients.
Didar Çolakoğlu, Humay İsmayilzade, Berk Büke, Kadriye Ağan, İpek Midi   +4 more
doaj   +1 more source

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

Epilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola, Marica Rubino, Antonella Riva, Pasquale Striano   +3 more
wiley   +1 more source