Results 111 to 120 of about 59,639 (336)

Management and prognosis of status epilepticus according to hospital setting: a prospective study. [PDF]

, 2009
BACKGROUND: The treatment of status epilepticus (SE) is based on relatively little evidence although several guidelines have been published. A recent study reported a worse SE prognosis in a large urban setting as compared to a peripheral hospital ...
Burnand, B., Foletti, G.B., Hayoz, D., Logroscino, G., Novy, J., Olivier, P., Rossetti, A.O., Ruffieux, C.   +7 more
core   +1 more source

Efficacy and tolerability of perampanel as add‐on therapy in Dravet syndrome: A prospective real‐world study

Epilepsia Open, EarlyView.
Abstract Objective To investigate the efficacy and tolerability of perampanel (PER) on Dravet syndrome in China by a prospective real‐world study. Methods We prospectively enrolled children with Dravet syndrome from the neurology clinic of Shenzhen Children's Hospital from September 2020 to October 2021.
Han Wang, Hong Chen, Xin Ding, Xueyan Cao, Jiahui Mai, Huafang Zou, Dongfang Zou, Yanwei Zhu, Jianxiang Liao, Dezhi Cao   +9 more
wiley   +1 more source

Surgical treatment of focal symptomatic refractory status epilepticus with and without invasive EEG

Epilepsy and Behavior Case Reports, 2015
Purpose: Neurosurgery appears to be a reasonable alternative in carefully selected patients with refractory status epilepticus (RSE) and super-refractory status epilepticus (SRSE).
Carolina Cuello Oderiz, Marina Aberastury, Ana Gabriela Besocke, Jorge Sinner, Betiana Comas-Guerrero, Carlos Alberto Ciraolo, Maria Concepción Pasteris, Walter Horacio Silva, María del Carmen García   +8 more
doaj   +1 more source

Clinically indicated electrical stimulation strategies to treat patients with medically refractory epilepsy. [PDF]

, 2018
Focal epilepsies represent approximately half of all diagnoses, and more than one-third of these patients are refractory to pharmacologic treatment.
Gurkoff, Gene, Izadi, Ali, Keselman, Inna, Ondek, Katelynn, Schedlbauer, Amber, Shahlaie, Kiarash   +5 more
core   +1 more source

Ketogenic diet therapy for epilepsy during pregnancy and lactation: An international survey exploring clinician perspectives

Epilepsia Open, EarlyView.
Abstract Objective Ketogenic diet therapies (KDTs) are increasingly used as a treatment for people with epilepsy of childbearing potential (PWECP) and glucose transporter type 1 deficiency syndrome (Glut1DS). The aim of this study was to collect information on clinical experience with KDT during pregnancy and lactation in these populations.
Kelly Faltersack, Tanya J. W. McDonald, Valentina De Giorgis, Bobbie Barron, Mackenzie C. Cervenka, Anita Devlin, Laura A. Healy, Magnhild Kverneland, Elles van der Louw, Mengyang Lu, Martina P. Zanaboni, Marisa Armeno, Elizabeth A. Felton   +12 more
wiley   +1 more source

Risk Factors Associated with Death in In-Hospital Pediatric Convulsive Status Epilepticus [PDF]

, 2012
Objective: To evaluate in-patient mortality and predictors of death associated with convulsive status epilepticus (SE) in a large, multi-center, pediatric cohort.
Alshekhlee, Amer, Gulati, Deepak, Kothare, Sanjeev Vithal, Koubeissi, Mohamad Z., Loddenkemper, Tobias, Ramgopal, Sriram, Syed, Tanvir U., Thanaviratananich, Sikawat   +7 more
core   +3 more sources

Efficacy and tolerability of fenfluramine with concomitant potassium bromide in patients with Dravet syndrome

Epilepsia Open, EarlyView.
Abstract Objective To assess the efficacy and tolerability of fenfluramine (FFA) with concomitant potassium bromide (BR) in patients with Dravet syndrome (DS). Methods This multicenter retrospective study, conducted within the German compassionate use program, analyzed BR doses and serum levels before and after FFA initiation, adverse events (AEs ...
Milka Pringsheim, Gerhard Kluger, Adam Strzelczyk, Susanne Schubert‐Bast, Thomas Mayer, Benjamin Glauche, Hiltrud Muhle, Michael Alber, Hartwig Spors, Tilmann Polster, Regina Trollmann, Gerhard Kurlemann, Markus Berndt, Kerstin A. Klotz   +13 more
wiley   +1 more source

Surgical management of status epilepticus: A systematic review

Epilepsia Open
Status Epilepticus (SE), unresponsive to medical management, is associated with high morbidity and mortality. Surgical management is typically considered in these refractory cases. The best surgical approach for affected patients remains unclear; however,
Rohan Jha, Sarah E. Blitz, Melissa M. J. Chua, Aaron E. L. Warren, Jong Woo Lee, John D. Rolston   +5 more
doaj   +1 more source

Indomethacin can downregulate the levels of inflammatory mediators in the hippocampus of rats submitted to pilocarpine-induced status epilepticus [PDF]

, 2014
OBJECTIVE: Refractory status epilepticus is one of the most life-threatening neurological emergencies and is characterized by high morbidity and mortality. Additionally, the use of anti-inflammatory drugs during this period is very controversial.
Argañaraz, Gustavo Adolfo, Cavalheiro, Esper Abrão, Naffah-Mazzacoratti, Maria da Graca, Perosa, Sandra Regina, Silva Junior, Jose Antonio, Vieira, Michele Juliane   +5 more
core   +5 more sources

Perampanel as a second‐line therapy to midazolam reduces soman‐induced status epilepticus and neurodegeneration in rats

Epilepsia Open, EarlyView.
Abstract Objective A benzodiazepine (diazepam or midazolam) is one of the current standards of care therapies to effectively terminate organophosphorus nerve agent‐induced status epilepticus when administered shortly after onset. Preclinical studies showed that benzodiazepines were less effective in stopping status epilepticus when treatment was ...
Hailey G. Steier, Caroline R. Schultz, Jerome Niquet, Donna A. Nguyen, Michael F. Stone, Abiel K. Biney, Marcio de Araujo Furtado, Claude G. Wasterlain, Lucille A. Lumley   +8 more
wiley   +1 more source