Results 61 to 70 of about 22,085 (271)

Intravenous ganaxolone in pediatric super-refractory status epilepticus: A single hospital experience

open access: yesEpilepsy & Behavior Reports, 2022
Synaptic GABAA receptor (GABAAR) internalization contributes to the drug resistant nature of super-refractory status epilepticus (SRSE). Ganaxolone is a 3β-methylated synthetic analog of the endogenous neuroactive steroid, allopregnanolone, that has ...
Rani K. Singh   +8 more
doaj   +1 more source

Throat and rectal swabs may have an important role in MRSA screening of critically ill patients.

open access: yes, 2008
OBJECTIVE: Methicillin-resistant Staphylococcus aureus (MRSA) is a major problem in intensive care units (ICU). International guidelines recommend screening patients for MRSA on admission, although consensus on sites required for optimum detection has ...
Batra, Rahul   +3 more
core   +1 more source

Retrospective, Multicenter Study of Lacosamide to Treat Neonatal Seizures

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Objective Most antiseizure medications (ASMs) are prescribed off label for neonates. Lacosamide's efficacy in infants and availability in intravenous formulation suggest potential utility for neonates. We evaluated the safety and efficacy of lacosamide for neonatal seizures. Methods This 10‐center, retrospective study of neonates with seizures
Alexandra Santana Almansa   +15 more
wiley   +1 more source

Treatment Options in the Management of Status Epilepticus [PDF]

open access: yes, 2018
Opinion statement: Status epilepticus treatment involves the use of several pharmacologic compounds, which are conceptually divided into three successive and additional lines of action.
Rossetti, Andrea
core  

Newer Antiepileptic Drugs in Status Epilepticus: Prescription Trends and Outcomes in Comparison with Traditional Agents. [PDF]

open access: yes, 2017
Newer antiepileptic drugs (AEDs) are increasingly prescribed; however, relatively limited data are available regarding their use in status epilepticus (SE) and the impact on outcome.
Beuchat, I., Novy, J., Rossetti, A.O.
core   +1 more source

Efficacy of vagus nerve stimulator during transition to adulthood in patients with treatment‐resistant epilepsy

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective To evaluate the efficacy of vagus nerve stimulation (VNS) as an adjunctive treatment in pediatric patients with treatment‐resistant epilepsy during the transition to adolescence. Methods We performed a retrospective cohort study of 30 children (ages 2–18 years) with medication‐resistant epilepsy who underwent VNS implantation between
Jonadab dos Santos Silva   +4 more
wiley   +1 more source

New-onset refractory status epilepticus (NORSE) in paediatric patients: causes, characteristics and outcomes

open access: yesBMJ Neurology Open, 2022
Background New-onset refractory status epilepticus (NORSE) refers to patients without a previous history of seizures who have refractory status epilepticus for at least 72 hours without an identified aetiology. Despite the severe neurological sequelae of
Francisco Bruno   +10 more
doaj   +1 more source

Status epilepticus [PDF]

open access: yes, 2008
INTRODUÇÃO: O estado de mal epiléptico (EME) é subdiagnosticado, especialmente as formas clínicas com sinais motores sutis ou apenas com alteração da consciência.
GARZON, Eliana
core   +1 more source

Resolution of generalized tonic seizures following focal ablative or resective surgery

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective Focal brain lesions may underlie generalized tonic seizures, as seen in Lennox–Gastaut syndrome, by engaging bilateral neural networks. However, this seizure type is often not considered surgically remediable. Here, we describe the resolution of apparent electroclinically classic generalized tonic seizures in children originating ...
Sem L. Kampman   +3 more
wiley   +1 more source

A practical approach to in-hospital management of new-onset refractory status epilepticus/febrile infection related epilepsy syndrome

open access: yesFrontiers in Neurology, 2023
New-onset refractory status epilepticus (NORSE) is “a clinical presentation, not a specific diagnosis, in a patient without active epilepsy or other preexisting relevant neurological disorder, with new onset of refractory status epilepticus without a ...
Zubeda Sheikh   +2 more
doaj   +1 more source

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