Neurological manifestations may be common in COVID-19 patients. They may include several syndromes, such as a suggested autoimmune abnormal response, which may result in encephalitis and new-onset refractory status epilepticus (NORSE).
P. Manganotti+6 more
semanticscholar +1 more source
Refractory status epilepticus in adults
The management of status epilepticus has improved over the past 20 years, resulting in a substantial decrease in the associated morbidity and mortality. Patients who have seizures that are refractory to initial pharmacologic interventions tend to have significant underlying toxic, metabolic, structural, or infectious disorders, and therefore management
Division of Emergency Medicine, University of Florida, Jacksonville, Florida, USA ( host institution )+2 more
openaire +4 more sources
Status Epilepticus and Beyond: A Clinical Review of Status Epilepticus and an Update on Current Management Strategies in Super-refractory Status Epilepticus [PDF]
Status epilepticus and refractory status epilepticus represent some of the most complex conditions encountered in the neurological intensive care unit. Challenges in management are common as treatment options become limited and prolonged hospital courses
Roy Poblete, Gene Sung
doaj +1 more source
Treatment of pediatric convulsive status epilepticus
Status epilepticus is one of the most common life-threatening neurological emergencies in childhood with the highest incidence in the first 5 years of life and high mortality and morbidity rates.
Lena-Luise Becker+11 more
doaj +1 more source
Increased expression of matrix metalloproteinase-9 in patients with temporal lobe epilepsy [PDF]
Aim: The molecular mechanism of epileptogenesis in temporal lobe epilepsy is still unclear. Experimental studies have suggested that matrix metalloproteinases have important roles in this process, but human studies are limited.
Acar, Feridun+3 more
core +1 more source
Isoflurane in (Super-) Refractory Status Epilepticus: A Multicenter Evaluation
We aimed to determine the association between seizure termination and side effects of isoflurane for the treatment of refractory status epilepticus (RSE) and super-refractory status epilepticus (SRSE) in neurointensive care units (neuro-ICUs). This was a
H. Stetefeld+16 more
semanticscholar +1 more source
Treatment of Refractory and Super-refractory Status Epilepticus [PDF]
Refractory and super-refractory status epilepticus (SE) are serious illnesses with a high risk of morbidity and even fatality. In the setting of refractory generalized convulsive SE (GCSE), there is ample justification to use continuous infusions of highly sedating medications-usually midazolam, pentobarbital, or propofol. Each of these medications has
Samhitha Rai, Frank W. Drislane
openaire +3 more sources
Super-refractory status epilepticus in adults
Abstract Introduction Super-refractory status epilepticus (SRSE) represents the culmination of refractory status epilepticus (RSE) and carries a significant risk of poor neurological outcome and high mortality. RSE is not defined primarily by seizure duration, but by failure to respond to appropriate antiseizure ...
Michael P Malter, Janina Neuneier
openaire +3 more sources
Vagus Nerve Stimulation (VNS) in Super Refractory New Onset Refractory Status Epilepticus (NORSE)
The treatment protocol of status epilepticus has many associated toxicities so there is interest in alternate nonmedicinal therapies for managing New Onset Refractory Status Epilepticus (NORSE) patients.
Mohankumar Kurukumbi+3 more
doaj +1 more source
"Electro-clinical Syndromes" with onset in Paediatric Age. the highlights of the clinical-EEG, genetic and therapeutic advances [PDF]
The genetic causes underlying epilepsy remain largely unknown, and the impact of available genetic data on the nosology of epilepsy is still limited.
Alberto Verrotti+7 more
core +2 more sources