Results 71 to 80 of about 59,639 (336)

The use of levetiracetam in refractory status epilepticus [PDF]

Seizure, 2006
Six patients with status epilepticus (SE) of various etiologies refractory to at least two antiepileptic drugs (AEDs) had complete cessation of their seizures following administration of oral levetiracetam (LEV). Seizure types included convulsive, focal, and nonconvulsive status epilepticus.
Andrew N. Wilner, Jerzy P. Szaflarski, Ivan R. Landan, Jeffrey Levin, Nitin Patel   +4 more
openaire   +2 more sources

Super-Refractory Status Epilepticus: Prognosis and Recent Advances in Management

Aging and Disease, 2021
Super-refractory status epilepticus (SRSE) is a life-threatening neurological emergency with high morbidity and mortality. It is defined as “status epilepticus (SE) that continues or recurs 24 hours or more after the onset of anesthesia, including those ...
Batool F. Kirmani, K. Au, Lena Ayari, Marita John, Padmashri A. Shetty, R. Delorenzo   +5 more
semanticscholar   +1 more source

Predictors of Outcome in Refractory Status Epilepticus [PDF]

JAMA Neurology, 2012
To further characterize the demographics, outcomes, and prognostic factors for refractory status epilepticus (RSE).Retrospective analysis of all the episodes of RSE treated between January 1, 1999, and August 30, 2011.Neurointensive care unit within a tertiary referral center, Mayo Clinic, Rochester, Minnesota.Refractory status epilepticus was defined ...
Jeffrey W. Britton, Alejandro A. Rabinstein, Jayawant N. Mandrekar, E. F. M. Wijdicks, Sara E. Hocker   +4 more
openaire   +3 more sources

Dietary Management of Children With Super-Refractory Status Epilepticus: A Systematic Review and Experience in a Single UK Tertiary Centre

Frontiers in Neurology, 2021
Ketogenic diet therapies (KDT) are high-fat, low carbohydrate diets used as an effective treatment option for drug-resistant epilepsy. There is limited research on the efficacy of KDT for super-refractory status epilepticus (SRSE).
N. Schoeler, Zoe Simpson, R. Zhou, S. Pujar, C. Eltze, J. Cross   +5 more
semanticscholar   +1 more source

‘The great imitator’: Neurosyphilis and new-onset refractory status epilepticus (NORSE) syndrome

Epilepsy and Behavior Case Reports, 2015
New-onset refractory status epilepticus (NORSE) is a syndrome of new-onset drug resistant status epilepticus that often has a catastrophic outcome. A 30-year-old man of Somali origin presented with refractory status to a district general hospital.
Sonia Kumari, Tom Hayton, Pauline Jumaa, Dougall McCorry   +3 more
doaj   +1 more source

Factors associated with long‐term outcomes in pediatric refractory status epilepticus

Epilepsia, 2021
This study was undertaken to describe long‐term clinical and developmental outcomes in pediatric refractory status epilepticus (RSE) and identify factors associated with new neurological deficits after RSE.
Marina Gaínza-Lein, Cristina Barcia Aguilar, J. Piantino, K. Chapman, Iván Sánchez Fernández, Marta Amengual-Gual, A. Anderson, Brian L. Appavu, R. Arya, J. Brenton, J. Carpenter, Justice Clark, R. Farias-Moeller, W. Gaillard, T. Glauser, Joshua L. Goldstein, H. Goodkin, L. Huh, Robert J. Kahoud, K. Kapur, Y. Lai, T. McDonough, M. Mikati, L. Morgan, Anuranjita Nayak, E. Novotny, A. Ostendorf, E. Payne, K. Peariso, Latania Reece, J. Riviello, Kumar Sannagowdara, T. Sands, T. Sheehan, R. Tasker, D. Tchapyjnikov, A. Vásquez, M. Wainwright, A. Wilfong, Korwyn L Williams, Bo Zhang, T. Loddenkemper   +41 more
semanticscholar   +1 more source

Pediatric refractory and super-refractory status epilepticus [PDF]

Seizure, 2019
To summarize the available evidence related to pediatric refractory status epilepticus (RSE) and super-refractory status epilepticus (SRSE), with emphasis on epidemiology, etiologies, therapeutic approaches, and clinical outcomes.Narrative review of the medical literature using MEDLINE database.RSE is defined as status epilepticus (SE) that fails to ...
Alejandra Vasquez, Raquel Farias-Moeller, William Tatum   +2 more
openaire   +3 more sources

Evolution of Cerebral Atrophy in a Patient with Super Refractory Status Epilepticus Treated with Barbiturate Coma

Case Reports in Neurological Medicine, 2017
Introduction. Status epilepticus is associated with neuronal breakdown. Radiological sequelae of status epilepticus include diffusion weighted abnormalities and T2/FLAIR cortical hyperintensities corresponding to the epileptogenic cortex.
Christopher R. Newey, Pravin George, Premkumar Nattanmai, Christine Ahrens, Stephen Hantus, Aarti Sarwal   +5 more
doaj   +1 more source

Newer Antiepileptic Drugs in Status Epilepticus: Prescription Trends and Outcomes in Comparison with Traditional Agents. [PDF]

, 2017
Newer antiepileptic drugs (AEDs) are increasingly prescribed; however, relatively limited data are available regarding their use in status epilepticus (SE) and the impact on outcome.
Beuchat, I., Novy, J., Rossetti, A.O.
core   +1 more source

The DEC2‐SCN2A Axis is Essential for the Anticonvulsant Effects of Cannabidiol by Modulating Neuronal Plasticity

Advanced Science, EarlyView.
This study identifies DEC2 as a critical transcriptional repressor of Scn2a that directly binds E‐box motifs in its promoter to regulate neuronal plasticity and epileptogenesis. Functional manipulation of DEC2 alters seizure susceptibility in vivo. Cannabidiol enhances this repression, unveiling a novel DEC2‐SCN2A axis underlying its anticonvulsant ...
Huifang Song, Yifan Wang, Lili Wang, Chang Guo, Shiqi Liu, Yi Rong, Jiawen Tian, Chao Peng, Yuying Shao, Zhixiong Ma, Na Li, Jingliang Zhang, Zijun Peng, Xu Yan, Hangwei Fa, Xinyue Ma, Jie Dong, Jinping Ji, Chen Yang, Haocheng Chen, Jing Liang, Qi Sun, Yang Yang, Weining Ma, Zhuo Huang   +24 more
wiley   +1 more source