Results 21 to 30 of about 2,119,196 (409)

The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1941-1952, December 2022., 2022
Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee, Graeme S. V. McDowell, Darryl C. De Vivo, Daniel Friedman, Samuel F. Berkovic, Maria Spanou, Argirios Dinopoulos, Katheryn Grand, Pedro A. Sanchez‐Lara, Michelle Allen‐Sharpley, Jodi Warman‐Chardon, Alexander Solyom, Thierry Levade, Edward H. Schuchman, Steffany A. L. Bennett, David A. Dyment, Toni S. Pearson   +16 more
wiley   +1 more source

State of health estimation of Li-ion batteries with regeneration phenomena: a similar rest time-based prognostic framework [PDF]

, 2016
State of health (SOH) prediction in Li-ion batteries plays an important role in intelligent battery management systems (BMS). However, the existence of capacity regeneration phenomena remains a great challenge for accurately predicting the battery SOH ...
Guo, Jianbin, Qin, Taichun, Skaf, Zakwan, Zeng, Shengkui   +3 more
core   +2 more sources

Parental perspectives long term after neonatal clinical trial participation: a survey

Trials, 2020
Background Although recruiting newborns is ethically challenging, clinical trials remain essential to improve neonatal care. There is a lack of empirical data on the parental perspectives following participation of their neonate in a clinical trial ...
Thomas Salaets, Emilie Lavrysen, Anne Smits, Sophie Vanhaesebrouck, Maissa Rayyan, Els Ortibus, Jaan Toelen, Laurence Claes, Karel Allegaert   +8 more
doaj   +1 more source

Exosomes derived from stem cells of human deciduous exfoliated teeth inhibit angiogenesis in vivo and in vitro via the transfer of miR-100-5p and miR-1246

Stem Cell Research & Therapy, 2022
Background Anti-angiogenic therapy has been shown to be a promising strategy for anti-tumor treatment. Increasing evidence indicates that tumor angiogenesis is affected by exosomes that are secreted by mesenchymal stem cells (MSCs), but whether exosomes ...
Panpan Liu, Qun Zhang, Jun Mi, Shuangshuang Wang, Qiuping Xu, Dexuan Zhuang, Wenqian Chen, Chang Liu, Liwei Zhang, Jing Guo, Xunwei Wu   +10 more
doaj   +1 more source

Development of new all-optical signal regeneration technique [PDF]

, 2017
All-optical signal regeneration have been the active research area since last decade due to evolution of nonlinear optical signal processing. Existing all-optical signal regeneration techniques are agitated in producing low Bit Error Rate (BER) of 10-10 ...
A Mohajerin-Ariaei, AE Willner, B Das, B Das, Bhagwan Das, Bishwajeet Pandey, C Lundström, F Parmigiani, F Wen, H Zhu, I Kaminow, J Wang, L Jones, Labeeb Mohammed Adam Ahmed, M Kagawa, Mohammad Faiz Liew Abdullah, Nor Shahida Mohd Shah, R Damani, R Slavík, SL Olsson, Z Chen, Z Tong   +21 more
core   +1 more source

Early redox activities modulate Xenopus tail regeneration. [PDF]

, 2018
Redox state sustained by reactive oxygen species (ROS) is crucial for regeneration; however, the interplay between oxygen (O2), ROS and hypoxia-inducible factors (HIF) remains elusive.
Ferreira, Fernando, Luxardi, Guillaume, Raghunathan, VijayKrishna, Zhao, Min, Zhu, Kan   +4 more
core   +2 more sources

Improving the regenerative potential of olfactory ensheathing cells by overexpressing prostacyclin synthetase and its application in spinal cord repair

Journal of Biomedical Science, 2017
Background Olfactory ensheathing cells (OEC), specialized glia that ensheathe bundles of olfactory nerves, have been reported as a favorable substrate for axonal regeneration.
May-Jywan Tsai, Chi-Ting Huang, Yong-San Huang, Ching-Feng Weng, Song-Kun Shyue, Ming-Chao Huang, Dann-Ying Liou, Yan-Ru Lin, Chu-Hsun Cheng, Huai-Sheng Kuo, Yilo Lin, Meng-Jen Lee, Wen-Hung Huang, Wen-Cheng Huang, Henrich Cheng   +14 more
doaj   +1 more source

Erythropoietin Activates Autophagy to Regulate Apoptosis and Angiogenesis of Periodontal Ligament Stem Cells via the Akt/ERK1/2/BAD Signaling Pathway under Inflammatory Microenvironment

Stem Cells International, 2022
Background. Angiogenic tissue engineering is a vital problem waiting to be settled for periodontal regeneration. Erythropoietin, a multieffect cytokine, has been reported as a protective factor for cell fate.
Denghao Huang, Jie Lei, Xingrui Li, Zhonghao Jiang, Maoxuan Luo, Yao Xiao   +5 more
doaj   +1 more source

Switching on regeneration [PDF]

Stem Cell Investigation, 2016
The limited ability of mammals to repair damaged tissues and organs is well known, and possibilities to improve regeneration are highly desired. Sun et al. (1) ( Cell Stem Cell , 2016) recently reported that deleting the Arid1a gene in mice greatly enhances the ability to regenerate the liver and ears after induced injury.
van der Vaart, A., van den Heuvel, Sander   +1 more
openaire   +5 more sources

METTL3 Promotes Osteo/Odontogenic Differentiation of Stem Cells by Inhibiting miR-196b-5p Maturation

Stem Cells International, 2023
Mesenchymal stem cells (MSCs) have been considered a potential method for the regeneration of tooth and maxillofacial bone defects based on the multidirectional differentiation characteristics of MSCs.
Xiao Han, Guoyue Li, Haoqing Yang, Chen Zhang, Yangyang Cao, Ning Wang, Lihua Ge, Zhipeng Fan   +7 more
doaj   +1 more source