Entering and leaving employment in deprived neighbourhoods undergoing area regeneration [PDF]
, 2018 Concentrations of worklessness have been persistent in the UK for several decades but have not been tackled effectively by policy. An individualised approach to unemployment has existed, alongside employment policies without a strong geographical ...
Kearns, Ade, Mason, Phil
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Rapid reversion from monomer to dimer regenerates the ultraviolet-B photoreceptor UV RESISTANCE LOCUS8 in intact arabidopsis plants [PDF]
, 2013 Arabidopsis (Arabidopsis thaliana) UV RESISTANCE LOCUS8 (UVR8) is a photoreceptor that specifically mediates photomorphogenic responses to ultraviolet (UV)-B in plants.
Heilmann, M., Jenkins, G.I.
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Journal of Hepatology, 2006 During liver regeneration after partial hepatectomy, normally quiescent hepatocytes undergo one or two rounds of replication to restore the liver mass by a process of compensatory hyperplasia. A large number of genes are involved in liver regeneration, but the essential circuitry required for ...
Fausto, Nelson +2 more
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Parental perspectives long term after neonatal clinical trial participation: a survey
Trials, 2020 Background Although recruiting newborns is ethically challenging, clinical trials remain essential to improve neonatal care. There is a lack of empirical data on the parental perspectives following participation of their neonate in a clinical trial ...
Thomas Salaets +8 more
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METTL3 Promotes Osteo/Odontogenic Differentiation of Stem Cells by Inhibiting miR-196b-5p Maturation
Stem Cells International, 2023 Mesenchymal stem cells (MSCs) have been considered a potential method for the regeneration of tooth and maxillofacial bone defects based on the multidirectional differentiation characteristics of MSCs.
Xiao Han +7 more
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Efficient β-cell regeneration by a combination of neogenesis and replication following β-cell ablation and reversal of pancreatic duct ligation. [PDF]
, 2013 Achieving efficient β-cell regeneration is a major goal of diabetes research. Previously, we found that a combination of β-cell ablation and pancreatic duct ligation led to β-cell regeneration by direct conversion from α-cells.
Hao, Ergeng +2 more
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Scientific Reports, 2017 Cartilage tissue is avascular and hypoxic which regulates chondrocyte phenotype via stabilization of HIFs. Here, we investigated the role of hypoxia and HIFs in regulation of Rho and canonical Wnt signaling in chondrocytes.
Ece Öztürk +4 more
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The action of obestatin in skeletal muscle repair: stem cell expansion, muscle growth, and microenvironment remodeling [PDF]
, 2015 The development of therapeutic strategies for skeletal muscle diseases, such as physical injuries and myopathies, depends on the knowledge of regulatory signals that control the myogenic process. The obestatin/GPR39 system operates as an autocrine signal
ADAMO, Sergio +16 more
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Journal of Cellular Physiology, 2007 AbstractLiver regeneration after partial hepatectomy is a very complex and well‐orchestrated phenomenon. It is carried out by the participation of all mature liver cell types. The process is associated with signaling cascades involving growth factors, cytokines, matrix remodeling, and several feedbacks of stimulation and inhibition of growth related ...
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The lncRNA GATA6-AS epigenetically regulates endothelial gene expression via interaction with LOXL2
Nature Communications, 2018 LncRNAs influence endothelial cell function via a number of mechanisms. Here the authors show that the lncRNA GATA6-AS regulates endothelial gene expression through interaction with the nuclear deaminase LOXL2, with functional consequences on endothelial-
Philipp Neumann +11 more
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