Results 41 to 50 of about 1,340,212 (344)
Stem Cell Research & Therapy, 2020 Background In recent years, significant progress has been made in developing highly complex tissue-engineered skin substitutes (TESSs) for wound healing. However, the lack of skin appendages, such as hair follicles and sweat glands, and the time required,
Qun Zhang +9 more
doaj +1 more source
Closing the loop for hydrogen storage: Facile regeneration of NaBH4 from its hydrolytic product.
Angewandte Chemie, 2020 Sodium borohydride (NaBH4 ) is among the most studied hydrogen storage materials since it is able to deliver high purity H2 at room temperature with controllable kinetics via hydrolysis, but its regeneration from the hydrolytic product has been ...
Yongyang Zhu +7 more
semanticscholar +1 more source
A Specific Mini‐Intrabody Mediates Lysosome Degradation of Mutant Huntingtin
Advanced Science, 2023 Accumulation of misfolded proteins leads to many neurodegenerative diseases that can be treated by lowering or removing mutant proteins. Huntington's disease (HD) is characterized by the intracellular accumulation of mutant huntingtin (mHTT) that can be ...
Caijuan Li +16 more
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FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Communications BiologyThe accumulation of α-synuclein induces neuronal loss in midbrain nuclei and leads to the disruption of motor circuits, while the pathology of α-synuclein in cortical regions remains elusive.
Borui Zhang +8 more
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Tenophages: a novel macrophage-like tendon cell population expressing CX3CL1 and CX3CR1
Disease Models & Mechanisms, 2019 Tendon disorders frequently occur and recent evidence has clearly implicated the presence of immune cells and inflammatory events during early tendinopathy. However, the origin and properties of these cells remain poorly defined.
Christine Lehner +9 more
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Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Frontiers in Oncology, 2022 Exosomes secreted by cancer cells are important components in the tumor microenvironment, enabling cancer cells to communicate with each other and with noncancerous cells to play important roles in tumor progression and metastasis.
Dexuan Zhuang +15 more
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