Results 61 to 70 of about 2,200,062 (357)

The lncRNA GATA6-AS epigenetically regulates endothelial gene expression via interaction with LOXL2

open access: yesNature Communications, 2018
LncRNAs influence endothelial cell function via a number of mechanisms. Here the authors show that the lncRNA GATA6-AS regulates endothelial gene expression through interaction with the nuclear deaminase LOXL2, with functional consequences on endothelial-
Philipp Neumann   +11 more
doaj   +1 more source

Preterm birth impairs postnatal lung development in the neonatal rabbit model

open access: yesRespiratory Research, 2020
Background Bronchopulmonary dysplasia continues to cause important respiratory morbidity throughout life, and new therapies are needed. The common denominator of all BPD cases is preterm birth, however most preclinical research in this area focusses on ...
Thomas Salaets   +10 more
doaj   +1 more source

Chalk and Cheese: A comparison of England and Scotland’s emerging approaches to regeneration [PDF]

open access: yes, 2012
To suggest that the Department for Communities and Local Government’s (DCLG’s) publication Regeneration to Enable Growth: What Government Is Doing in Support of Community-Led Regeneration, issued in early 2011, was a disappointment to many is something ...
Errington, Barry   +4 more
core  

HDAC4 regulates skeletal muscle regeneration via soluble factors [PDF]

open access: yes, 2018
Skeletal muscle possesses a high ability to regenerate after an insult or in pathological conditions, relying on satellite cells, the skeletal muscle stem cells.
Alessandra Renzini   +5 more
core   +3 more sources

Heart regeneration [PDF]

open access: yesNature, 2011
Heart failure plagues industrialized nations, killing more people than any other disease. It usually results from a deficiency of specialized cardiac muscle cells known as cardiomyocytes, and a robust therapy to regenerate lost myocardium could help millions of patients every year.
Michael A, Laflamme, Charles E, Murry
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Afterword: Less is the New More

open access: yesRegeneration
This afterword to the special issue discusses the author’s affective experiences with energy transition. The particular focus is the affective promise of electrification as a means to rupture the ecological emergency generated by today’s petroculture.
Dominic Boyer
doaj   +2 more sources

Central nervous system regeneration.

open access: yesCell, 2022
Neurons of the mammalian central nervous system fail to regenerate. Substantial progress has been made toward identifying the cellular and molecular mechanisms that underlie regenerative failure and how altering those pathways can promote cell survival ...
Supraja G. Varadarajan   +4 more
semanticscholar   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Introduction: On the Cold Edge: Environment, Art, Culture and the Arctic Circle

open access: yesRegeneration
A multimodal collaboration between artists, writers, and scholars. This piece emerged from an expedition to the Arctic archipelago as part of the Arctic Circle Residency in Autumn 2022.
Candace N Jensen   +2 more
doaj   +2 more sources

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