Results 61 to 70 of about 964,799 (310)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Chalk and Cheese: A comparison of England and Scotland’s emerging approaches to regeneration [PDF]
, 2012 To suggest that the Department for Communities and Local Government’s (DCLG’s) publication Regeneration to Enable Growth: What Government Is Doing in Support of Community-Led Regeneration, issued in early 2011, was a disappointment to many is something ...
Errington, Barry +4 more
core
Periodontal regeneration [PDF]
Australian Dental Journal, 2009 AbstractThe ultimate goal of periodontal therapy is the regeneration of the tissues destroyed as a result of periodontal disease. Currently, two clinical techniques, based on the principles of “guided tissue regeneration” (GTR) or utilization of the biologically active agent “enamel matrix derivative” (EMD), can be used for the regeneration of ...
openaire +5 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
, 2010 community , New Labour , regeneration , UK ,
WALLACE, ANDREW, ANDREW WALLACE
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Cell Stem CellRegeneration is a heroic biological process that restores tissue architecture and function in the face of day-to-day cell loss or the aftershock of injury. Capacities and mechanisms for regeneration can vary widely among species, organs, and injury contexts.
Poss, Kenneth D., Tanaka, Elly M.
openaire +2 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Externally imposed electric field enhances plant root tip regeneration [PDF]
, 2016 In plants, shoot and root regeneration can be induced in the distinctive conditions of tissue culture (in vitro), but is also observed in intact individuals (in planta) recovering from tissue damage. Roots, for example, can regenerate their fully excised
Sena, G, Hanna Ougolnikova, A, Kral, N
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Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
c-Jun reprograms Schwann cells of injured nerves to generate a repair cell essential for regeneration. [PDF]
, 2012 The radical response of peripheral nerves to injury (Wallerian degeneration) is the cornerstone of nerve repair. We show that activation of the transcription factor c-Jun in Schwann cells is a global regulator of Wallerian degeneration.
Jenkins, Billy +33 more
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