Results 11 to 20 of about 157,048 (284)
Tissue repair brakes: A common paradigm in the biology of regeneration [PDF]
Stem Cells, 2019 Abstract To date, most attention on tissue regeneration has focused on the exploration of positive cues promoting or allowing the engagement of natural cellular restoration upon injury. In contrast, the signals fostering cell identity maintenance in the vertebrate body have been poorly investigated; yet they are crucial, for their ...
Valentina Cigliola +3 more
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Fibroblast Growth Factors: Biology, Function, and Application for Tissue Regeneration [PDF]
Journal of Tissue Engineering, 2010 Fibroblast growth factors (FGFs) that signal through FGF receptors (FGFRs) regulate a broad spectrum of biological functions, including cellular proliferation, survival, migration, and differentiation. The FGF signal pathways are the RAS/MAP kinase pathway, PI3 kinase/AKT pathway, and PLCγ pathway, among which the RAS/MAP kinase pathway is known to be ...
Ye‐Rang Yun +8 more
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Biology Explaining Tooth Repair and Regeneration: A Mini-Review [PDF]
Gerontology, 2018 The tooth is an intricate composition of precisely patterned, mineralized matrices and soft tissues. Mineralized tissues include enamel (produced by the epithelial cells called ameloblasts), dentin and cementum (produced by mesenchymal cells called odontoblasts and cementoblasts, respectively), and soft tissues, which include the dental pulp and the ...
Anamaria Balic
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Commonalities in the endocrinology of stem cell biology and organ regeneration [PDF]
Molecular and Cellular Endocrinology, 2008 International ...
Neil A. Hanley
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Arthritis Research & Therapy, 2021 Background Self-efficacy, or patients’ confidence in their ability to control disease and its consequences, was recently prioritised in EULAR recommendations for inflammatory arthritis self-management strategies. However, it remains unclear which factors
Doumen Michaël +6 more
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Arthritis Research & Therapy, 2021 An amendment to this paper has been published and can be accessed via the original article.
Michaël Doumen +6 more
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A novel retinal ganglion cell quantification tool based on deep learning
Scientific Reports, 2021 Glaucoma is a disease associated with the loss of retinal ganglion cells (RGCs), and remains one of the primary causes of blindness worldwide. Major research efforts are presently directed towards the understanding of disease pathogenesis and the ...
Luca Masin +7 more
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MMP2 Modulates Inflammatory Response during Axonal Regeneration in the Murine Visual System
Cells, 2021 Neuroinflammation has been put forward as a mechanism triggering axonal regrowth in the mammalian central nervous system (CNS), yet little is known about the underlying cellular and molecular players connecting these two processes.
Lien Andries +11 more
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A Chemical Biology Approach to Myocardial Regeneration [PDF]
Journal of Cardiovascular Translational Research, 2011 Heart failure is one of the major causes of death in the Western world because cardiac muscle loss is largely irreversible and can lead to a relentless decline in cardiac function. Novel therapies are needed since the only therapy to effectively replace lost myocytes today is transplantation of the entire heart.
Erik Willems +6 more
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Nature Communications, 2020 Mechanisms that regulate epithelial bending mainly link to cell shape changes, for example, the formation of wedge shaped cells. Here, the authors identify a different cell behaviour in the salivary glands and teeth where initial invagination arises by a
Jingjing Li +3 more
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