Regeneration Roadmap: database resources for regenerative biology
Regeneration plays an instrumental role in biological development and damage repair by constructing and replacing cells, tissues, and organs. Since regenerative capacity declines with age, promoting regeneration is heralded as a potential strategy for ...
Wang Kang +16 more
semanticscholar +3 more sources
Evolution, comparative biology and ontogeny of vertebrate heart regeneration [PDF]
There are 64,000 living species of vertebrates on our planet and all of them have a heart. Comparative analyses devoted to understanding the regenerative potential of the myocardium have been performed in a dozen vertebrate species with the aim of ...
Céline J. Vivien +2 more
semanticscholar +5 more sources
The cell biology of regeneration [PDF]
Regeneration of complex structures after injury requires dramatic changes in cellular behavior. Regenerating tissues initiate a program that includes diverse processes such as wound healing, cell death, dedifferentiation, and stem (or progenitor) cell proliferation; furthermore, newly regenerated tissues must integrate polarity and positional identity ...
R. King, Phillip A. Newmark
openalex +4 more sources
Implications of cellular and molecular biology advances in periodontal regeneration [PDF]
The mechanisms by which new periodontium is established on root surfaces previously exposed to periodontal disease has been an area of active research interest for the past decade.Recently, histological examination of periodontal regeneration has revealed a complex process orchestrated by temporo-spatial specific cell-matrix interactions.Advances in ...
Salomon Amar
openalex +4 more sources
Aspects of the biology of regeneration and repair in the human gastrointestinal tract [PDF]
The main pathways of epithelial differentiation in the intestine, Paneth, mucous, endocrine and columnar cell lineages are well recognized. However, in abnormal circumstances, for example in mucosal ulceration, a cell lineage with features distinct from these emerges, which has often been dismissed in the past as ‘pyloric’ metaplasia, because of its ...
Nicholas A. Wright
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Islet Cell Biology, Regeneration, and Transplantation [PDF]
Research studies centered on the biology, regeneration, and transplantation of islets continue to shed significant understanding on the development of different forms of diabetes and provide further impetus for the quest to find a “cure.” Diabetes is a manifestation of an inadequate mass of insulin-producing pancreatic beta-cells.
A. N. Balamurugan +3 more
doaj +3 more sources
The basis of liver regeneration: A systems biology approach
Introduction and aim. Liver regeneration is a normal response to liver injury. The aim of this study was to determine the molecular basis of liver regeneration, through an integrative analysis of high-throughput gene expression datasets. Material and methods.
Mamatha Bhat +7 more
openalex +4 more sources
Tissue repair brakes: A common paradigm in the biology of regeneration [PDF]
Abstract To date, most attention on tissue regeneration has focused on the exploration of positive cues promoting or allowing the engagement of natural cellular restoration upon injury. In contrast, the signals fostering cell identity maintenance in the vertebrate body have been poorly investigated; yet they are crucial, for their ...
Valentina Cigliola +3 more
openalex +5 more sources
Exosome-based therapeutics in bone regeneration: from fundamental biology to clinical translation. [PDF]
Tajafrooz F +7 more
europepmc +2 more sources
Fibroblast Growth Factors: Biology, Function, and Application for Tissue Regeneration [PDF]
Fibroblast growth factors (FGFs) that signal through FGF receptors (FGFRs) regulate a broad spectrum of biological functions, including cellular proliferation, survival, migration, and differentiation. The FGF signal pathways are the RAS/MAP kinase pathway, PI3 kinase/AKT pathway, and PLCγ pathway, among which the RAS/MAP kinase pathway is known to be ...
Ye‐Rang Yun +8 more
openalex +5 more sources

