Results 21 to 30 of about 1,651,358 (339)

Bionic microenvironment-inspired synergistic effect of anisotropic micro-nanocomposite topology and biology cues on peripheral nerve regeneration

open access: yesScience Advances, 2021
Anisotropic micro-nanocomposite topographies and biological cues can synergistically promote peripheral nerve regeneration. Anisotropic topographies and biological cues can simulate the regenerative microenvironment of nerve from physical and biological ...
Guicai Li   +8 more
semanticscholar   +1 more source

Comparative Biology of Vertebrate Retinal Regeneration: Restoration of Vision through Cellular Reprogramming.

open access: yesCold Spring Harbor Perspectives in Biology, 2021
The regenerative capacity of the vertebrate retina varies substantially across species. Whereas fish and amphibians can regenerate functional retina, mammals do not.
Levi Todd, T. Reh
semanticscholar   +1 more source

A novel retinal ganglion cell quantification tool based on deep learning

open access: yesScientific Reports, 2021
Glaucoma is a disease associated with the loss of retinal ganglion cells (RGCs), and remains one of the primary causes of blindness worldwide. Major research efforts are presently directed towards the understanding of disease pathogenesis and the ...
Luca Masin   +7 more
doaj   +1 more source

Treatment response and several patient-reported outcomes are early determinants of future self-efficacy in rheumatoid arthritis

open access: yesArthritis Research & Therapy, 2021
Background Self-efficacy, or patients’ confidence in their ability to control disease and its consequences, was recently prioritised in EULAR recommendations for inflammatory arthritis self-management strategies. However, it remains unclear which factors
Doumen Michaël   +6 more
doaj   +1 more source

Correction to: Treatment response and several patient-reported outcomes are early determinants of future self-efficacy in rheumatoid arthritis

open access: yesArthritis Research & Therapy, 2021
An amendment to this paper has been published and can be accessed via the original article.
Michaël Doumen   +6 more
doaj   +1 more source

A Chemical Biology Approach to Myocardial Regeneration [PDF]

open access: yesJournal of Cardiovascular Translational Research, 2011
Heart failure is one of the major causes of death in the Western world because cardiac muscle loss is largely irreversible and can lead to a relentless decline in cardiac function. Novel therapies are needed since the only therapy to effectively replace lost myocytes today is transplantation of the entire heart.
Erik Willems   +6 more
openaire   +3 more sources

MMP2 Modulates Inflammatory Response during Axonal Regeneration in the Murine Visual System

open access: yesCells, 2021
Neuroinflammation has been put forward as a mechanism triggering axonal regrowth in the mammalian central nervous system (CNS), yet little is known about the underlying cellular and molecular players connecting these two processes.
Lien Andries   +11 more
doaj   +1 more source

Biphasic Role of Tgf-β Signaling during Müller Glia Reprogramming and Retinal Regeneration in Zebrafish

open access: yesiScience, 2020
Summary: Tgf-β signaling is a major antiproliferative pathway governing different biological functions, including cellular reprogramming. Upon injury, Müller glial cells of zebrafish retina reprogram to form progenitors (MGPCs) essential for regeneration.
Poonam Sharma   +7 more
doaj   +1 more source

Ambystoma mexicanum, a model organism in developmental biology and regeneration: a colombian experience

open access: yesActa Biológica Colombiana, 2021
Ambystoma mexicanum is a urodele amphibian endemic to Xochimilco Lake in Mexico, it belongs to the salamander family Ambystomatidae. This species has frequently been used as model organism in developmental biology and regeneration laboratories around ...
Melisa Hincapie Agudelo   +3 more
doaj   +1 more source

Epithelial invagination by a vertical telescoping cell movement in mammalian salivary glands and teeth

open access: yesNature Communications, 2020
Mechanisms that regulate epithelial bending mainly link to cell shape changes, for example, the formation of wedge shaped cells. Here, the authors identify a different cell behaviour in the salivary glands and teeth where initial invagination arises by a
Jingjing Li   +3 more
doaj   +1 more source

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