Results 21 to 30 of about 1,844,796 (395)

Treatment response and several patient-reported outcomes are early determinants of future self-efficacy in rheumatoid arthritis

open access: yesArthritis Research & Therapy, 2021
Background Self-efficacy, or patients’ confidence in their ability to control disease and its consequences, was recently prioritised in EULAR recommendations for inflammatory arthritis self-management strategies. However, it remains unclear which factors
Doumen Michaël   +6 more
doaj   +1 more source

Comparative Biology of Vertebrate Retinal Regeneration: Restoration of Vision through Cellular Reprogramming.

open access: yesCold Spring Harbor Perspectives in Biology, 2021
The regenerative capacity of the vertebrate retina varies substantially across species. Whereas fish and amphibians can regenerate functional retina, mammals do not.
Levi Todd, T. Reh
semanticscholar   +1 more source

Correction to: Treatment response and several patient-reported outcomes are early determinants of future self-efficacy in rheumatoid arthritis

open access: yesArthritis Research & Therapy, 2021
An amendment to this paper has been published and can be accessed via the original article.
Michaël Doumen   +6 more
doaj   +1 more source

A novel retinal ganglion cell quantification tool based on deep learning

open access: yesScientific Reports, 2021
Glaucoma is a disease associated with the loss of retinal ganglion cells (RGCs), and remains one of the primary causes of blindness worldwide. Major research efforts are presently directed towards the understanding of disease pathogenesis and the ...
Luca Masin   +7 more
doaj   +1 more source

MMP2 Modulates Inflammatory Response during Axonal Regeneration in the Murine Visual System

open access: yesCells, 2021
Neuroinflammation has been put forward as a mechanism triggering axonal regrowth in the mammalian central nervous system (CNS), yet little is known about the underlying cellular and molecular players connecting these two processes.
Lien Andries   +11 more
doaj   +1 more source

A Chemical Biology Approach to Myocardial Regeneration [PDF]

open access: yesJournal of Cardiovascular Translational Research, 2011
Heart failure is one of the major causes of death in the Western world because cardiac muscle loss is largely irreversible and can lead to a relentless decline in cardiac function. Novel therapies are needed since the only therapy to effectively replace lost myocytes today is transplantation of the entire heart.
Erik Willems   +6 more
openaire   +3 more sources

The various routes to functional regeneration in the central nervous system [PDF]

open access: yes, 2020
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Echeverri, K.
Echeverri, Karen
core   +1 more source

Epithelial invagination by a vertical telescoping cell movement in mammalian salivary glands and teeth

open access: yesNature Communications, 2020
Mechanisms that regulate epithelial bending mainly link to cell shape changes, for example, the formation of wedge shaped cells. Here, the authors identify a different cell behaviour in the salivary glands and teeth where initial invagination arises by a
Jingjing Li   +3 more
doaj   +1 more source

A comprehensive conceptual and computational dynamics framework for autonomous regeneration of form and function in biological organisms [PDF]

open access: yes, 2022
In biology, regeneration is a mysterious phenomenon that has inspired self-repairing systems, robots, and biobots. It is a collective computational process whereby cells communicate to achieve an anatomical set point and restore original function in ...
Samarasinghe, Sandhya, Tran, NM-T
core   +1 more source

The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1941-1952, December 2022., 2022
Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee   +16 more
wiley   +1 more source

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