Results 21 to 30 of about 417,044 (314)

Prior Exposure to Immunosuppressors Sensitizes Retinal Microglia and Accelerates Optic Nerve Regeneration in Zebrafish

Mediators of Inflammation, 2019
As adult mammals lack the capacity to replace or repair damaged neurons, degeneration and trauma (and subsequent dysfunction) of the central nervous system (CNS) seriously constrains the patient’s life quality.
Ilse Bollaerts, Jessie Van houcke, An Beckers, Kim Lemmens, Sophie Vanhunsel, Lies De Groef, Lieve Moons   +6 more
doaj   +1 more source

Dual Targeting of Angipoietin‐1 and von Willebrand Factor by microRNA‐671‐5p Attenuates Liver Angiogenesis and Fibrosis

Hepatology Communications, 2022
Angipoietin‐1 (Angpt1) and von Willebrand factor (VWF) are two important angiogenic molecules that can drive pathologic angiogenesis and progression of liver fibrosis in our previous study.
Le Yang, Wenhui Yue, Hang Zhang, Zhi Zhang, Renmin Xue, Chengbin Dong, Fuquan Liu, Na Chang, Lin Yang, Liying Li   +9 more
doaj   +1 more source

Neutrophil Chemotaxis and NETosis in Murine Chronic Liver Injury via Cannabinoid Receptor 1/Gα_i/o/ROS/p38 MAPK Signaling Pathway

Cells, 2020
Neutrophils play an essential role in the control of inflammatory diseases. However, whether cannabinoid receptors (CBs) play a role in neutrophil chemotaxis and NETosis in sterile liver inflammation remains unknown.
Xuan Zhou, Le Yang, Xiaoting Fan, Xinhao Zhao, Na Chang, Lin Yang, Liying Li   +6 more
doaj   +1 more source

Potential use of human periapical cyst-mesenchymal stem cells (hPCy-MSCs) as a novel stem cell source for regenerative medicine applications [PDF]

, 2017
Mesenchymal stem cells (MSCs) are attracting growing interest by the scientific community due to their huge regenerative potential. Thus, the plasticity of MSCs strongly suggests the utilization of these cells for regenerative medicine applications.
Codispoti, Bruna, Marrelli, Massimo, Pacifici, Andrea, Pacifici, Luciano, Paduano, Francesco, Palmieri, Francesca, Tatullo, Marco   +6 more
core   +2 more sources

Cannabinoid Receptor 1 Participates in Liver Inflammation by Promoting M1 Macrophage Polarization via RhoA/NF-κB p65 and ERK1/2 Pathways, Respectively, in Mouse Liver Fibrogenesis

Frontiers in Immunology, 2017
Macrophage M1/M2 polarization mediates tissue damage and inflammatory responses. Cannabinoid receptor (CB) 1 participated in liver fibrogenesis by affecting bone marrow (BM)-derived monocytes/macrophages (BMMs) activation.
Lei Tian, Weiyang Li, Le Yang, Na Chang, Xiaoting Fan, Xiaofang Ji, Jieshi Xie, Lin Yang, Liying Li   +8 more
doaj   +1 more source

Publisher Correction: Exploring the effect of UV-C radiation on earthworm and understanding its genomic integrity in the context of H2AX expression

Scientific Reports, 2021
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Karthikeyan Subbiahanadar Chelladurai, Jackson Durairaj Selvan Christyraj, Ananthaselvam Azhagesan, Vennila Devi Paulraj, Muralidharan Jothimani, Beryl Vedha Yesudhason, Niranjan Chellathurai Vasantha, Mijithra Ganesan, Kamarajan Rajagopalan, Saravanakumar Venkatachalam, Johnson Benedict, Jemima Kamalapriya John Samuel, Johnson Retnaraj Samuel Selvan Christyraj   +12 more
doaj   +1 more source

DIP-2 suppresses ectopic neurite sprouting and axonal regeneration in mature neurons. [PDF]

, 2019
Neuronal morphology and circuitry established during early development must often be maintained over the entirety of animal lifespans. Compared with neuronal development, the mechanisms that maintain mature neuronal structures and architecture are little
Andrew D. Chisholm, Antonio Colavita, Carr, Chalfie, Chen, Chen, Chen, Coleman, Dickinson, Emoto, Finn, Hammarlund, Hayashi, Jan, Lee, Li, Li, Matter, Mukhopadhyay, Nathaniel Noblett, Nitta, Ouchi, Pan, Sanchez-Alvarez, Schmelz, Seungmee Park, Stephane Flibotte, Tank, Thorvaldsdóttir, Tony Roenspies, Toth, Wu, Yan, Yishi Jin, Zhang, Zhao Hua Ding, Zilu Wu   +36 more
core   +1 more source

Falsely normalized ankle-brachial index despite the presence of lower-extremity peripheral artery disease: two case reports

Journal of Medical Case Reports, 2021
Background The ankle-brachial index measurement is used for screening and diagnosis of lower-extremity peripheral artery disease and cardiovascular risk assessment.
Tatsuya Maruhashi, Shogo Matsui, Farina Mohamad Yusoff, Shinji Kishimoto, Masato Kajikawa, Yukihito Higashi   +5 more
doaj   +1 more source

Intestinal stem cell proliferation and epithelial homeostasis in the adult Drosophila midgut [PDF]

, 2015
Adult tissue homeostasis requires a tight balance between the removal of old or damaged cells and the production of new ones. Such processes are usually driven by dedicated stem cells that reside within specific tissue locations or niches.
Carroll, Lynsey, Cordero, Julia, Naszai, Mate   +2 more
core   +1 more source

Enhanced Hematopoietic Stem Cell Function Mediates Immune Regeneration following Sex Steroid Blockade

Stem Cell Reports, 2015
Mechanisms underlying age-related defects within lymphoid-lineages remain poorly understood. We previously reported that sex steroid ablation (SSA) induced lymphoid rejuvenation and enhanced recovery from hematopoietic stem cell (HSC) transplantation ...
Danika M. Khong, Jarrod A. Dudakov, Maree V. Hammett, Marc I. Jurblum, Sacha M.L. Khong, Gabrielle L. Goldberg, Tomoo Ueno, Lisa Spyroglou, Lauren F. Young, Marcel R.M. van den Brink, Richard L. Boyd, Ann P. Chidgey   +11 more
doaj   +1 more source