Results 41 to 50 of about 1,844,796 (395)
Stem Cell Reports, 2014 Age-related macular degeneration (AMD) causes severe visual impairment due in part to age-dependent impairment of retinal pigment epithelium (RPE). It has been suggested that autologous human induced pluripotent stem cells (hiPSCs) may represent a useful
Hiroyuki Kamao +7 more
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Regeneration review reprise [PDF]
, 2011 There have been notable advances in the scientific understanding of regeneration within the past year alone, including two recently published in BMC Biology. Increasingly, progress in the regeneration field is being inspired by comparisons with stem cell
Tabin, Clifford J, Whited, Jessica L
core +2 more sources
Archives of Neurology, 1999 A few brief years ago, damage to the central nervous system was generally perceived to be irreparable, and loss of neurons was largely viewed as an irreversible process. However, major advances in the study of neural progenitor cells have altered these perceptions, and rational approaches to the repair of the damaged nervous system using transplanted ...
John A. Kessler, Mark F. Mehler
openaire +2 more sources
Wnt signalling in intestinal stem cells: lessons from mice and flies [PDF]
, 2018 Adult stem cells play critical roles in the basal maintenance of tissue integrity, also known as homeostasis, and in tissue regeneration following damage. The highly conserved Wnt signalling pathway is a key regulator of stem cell fate.
Carroll, Lynsey +2 more
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NaNog: A pluripotency homeobox (master) molecule. [PDF]
, 2015 One of the most intriguing aspects of cell biology is the state of pluripotency, where the cell is capable of self-renewal for as many times as deemed necessary , then at a specified time can differentiate into any type of cell. This fundamental process
Aguib, YE +4 more
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The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future. [PDF]
, 2020 The respiratory system, which includes the trachea, airways, and distal alveoli, is a complex multi-cellular organ that intimately links with the cardiovascular system to accomplish gas exchange.
Basil, Maria C +15 more
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Stochastic gene expression drives mesophyll protoplast regeneration
Science Advances, 2021 Isolating protoplasts allows stochastic gene expression to enable regeneration of differentiated cells at a low frequency. Cell pluripotency is fundamental to biology.
Mengxue Xu +4 more
semanticscholar +1 more source
The Current Use of Stem Cells in Bladder Tissue Regeneration and Bioengineering. [PDF]
, 2017 Many pathological processes including neurogenic bladder and malignancy necessitate bladder reconstruction, which is currently performed using intestinal tissue. The use of intestinal tissue, however, subjects patients to metabolic abnormalities, bladder
Chan, Yvonne Y +3 more
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Peripheral Nerve Regeneration: Mechanism, Cell Biology, and Therapies [PDF]
BioMed Research International, 2014 Peripheral nerve injury has perplexed neuroscientists, neurologists, plastic surgeons, and bioengineers for decades. Despite the spontaneous ability of the adult peripheral nerve system to regenerate after injury, optimal and universal treatments capable of achieving full functional recovery are still unavailable.
Xiaofeng Jia +2 more
openaire +3 more sources
Mediators of Inflammation, 2019 As adult mammals lack the capacity to replace or repair damaged neurons, degeneration and trauma (and subsequent dysfunction) of the central nervous system (CNS) seriously constrains the patient’s life quality.
Ilse Bollaerts +6 more
doaj +1 more source