Results 41 to 50 of about 1,689,985 (299)

An Emerging Frontier in Intercellular Communication: Extracellular Vesicles in Regeneration

Frontiers in Cell and Developmental Biology, 2022
Regeneration requires cellular proliferation, differentiation, and other processes that are regulated by secreted cues originating from cells in the local environment. Recent studies suggest that signaling by extracellular vesicles (EVs), another mode of
Priscilla N. Avalos, David J. Forsthoefel   +1 more
semanticscholar   +1 more source

Cannabinoid Receptor 1 Participates in Liver Inflammation by Promoting M1 Macrophage Polarization via RhoA/NF-κB p65 and ERK1/2 Pathways, Respectively, in Mouse Liver Fibrogenesis

Frontiers in Immunology, 2017
Macrophage M1/M2 polarization mediates tissue damage and inflammatory responses. Cannabinoid receptor (CB) 1 participated in liver fibrogenesis by affecting bone marrow (BM)-derived monocytes/macrophages (BMMs) activation.
Lei Tian, Weiyang Li, Le Yang, Na Chang, Xiaoting Fan, Xiaofang Ji, Jieshi Xie, Lin Yang, Liying Li   +8 more
doaj   +1 more source

Dual Targeting of Angipoietin‐1 and von Willebrand Factor by microRNA‐671‐5p Attenuates Liver Angiogenesis and Fibrosis

Hepatology Communications, 2022
Angipoietin‐1 (Angpt1) and von Willebrand factor (VWF) are two important angiogenic molecules that can drive pathologic angiogenesis and progression of liver fibrosis in our previous study.
Le Yang, Wenhui Yue, Hang Zhang, Zhi Zhang, Renmin Xue, Chengbin Dong, Fuquan Liu, Na Chang, Lin Yang, Liying Li   +9 more
doaj   +1 more source

Neutrophil Chemotaxis and NETosis in Murine Chronic Liver Injury via Cannabinoid Receptor 1/Gα_i/o/ROS/p38 MAPK Signaling Pathway

Cells, 2020
Neutrophils play an essential role in the control of inflammatory diseases. However, whether cannabinoid receptors (CBs) play a role in neutrophil chemotaxis and NETosis in sterile liver inflammation remains unknown.
Xuan Zhou, Le Yang, Xiaoting Fan, Xinhao Zhao, Na Chang, Lin Yang, Liying Li   +6 more
doaj   +1 more source

Stochastic gene expression drives mesophyll protoplast regeneration

Science Advances, 2021
Isolating protoplasts allows stochastic gene expression to enable regeneration of differentiated cells at a low frequency. Cell pluripotency is fundamental to biology.
Mengxue Xu, Qingwei Du, Caihuan Tian, Ying Wang, Yuling Jiao   +4 more
semanticscholar   +1 more source

Enhanced Hematopoietic Stem Cell Function Mediates Immune Regeneration following Sex Steroid Blockade

Stem Cell Reports, 2015
Mechanisms underlying age-related defects within lymphoid-lineages remain poorly understood. We previously reported that sex steroid ablation (SSA) induced lymphoid rejuvenation and enhanced recovery from hematopoietic stem cell (HSC) transplantation ...
Danika M. Khong, Jarrod A. Dudakov, Maree V. Hammett, Marc I. Jurblum, Sacha M.L. Khong, Gabrielle L. Goldberg, Tomoo Ueno, Lisa Spyroglou, Lauren F. Young, Marcel R.M. van den Brink, Richard L. Boyd, Ann P. Chidgey   +11 more
doaj   +1 more source

Publisher Correction: Exploring the effect of UV-C radiation on earthworm and understanding its genomic integrity in the context of H2AX expression

Scientific Reports, 2021
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Karthikeyan Subbiahanadar Chelladurai, Jackson Durairaj Selvan Christyraj, Ananthaselvam Azhagesan, Vennila Devi Paulraj, Muralidharan Jothimani, Beryl Vedha Yesudhason, Niranjan Chellathurai Vasantha, Mijithra Ganesan, Kamarajan Rajagopalan, Saravanakumar Venkatachalam, Johnson Benedict, Jemima Kamalapriya John Samuel, Johnson Retnaraj Samuel Selvan Christyraj   +12 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Graft survival of major histocompatibility complex deficient stem cell-derived retinal cells

Communications Medicine
Background Gene editing of immunomodulating molecules is a potential transplantation strategy to control immune rejection. As we noticed the successful transplantation of retinal pigment epithelium (RPE) derived from embryonic stem cells of a cynomolgus ...
Masaaki Ishida, Tomohiro Masuda, Noriko Sakai, Yoko Nakai-Futatsugi, Hiroyuki Kamao, Takashi Shiina, Masayo Takahashi, Sunao Sugita   +7 more
doaj   +1 more source

Falsely normalized ankle-brachial index despite the presence of lower-extremity peripheral artery disease: two case reports

Journal of Medical Case Reports, 2021
Background The ankle-brachial index measurement is used for screening and diagnosis of lower-extremity peripheral artery disease and cardiovascular risk assessment.
Tatsuya Maruhashi, Shogo Matsui, Farina Mohamad Yusoff, Shinji Kishimoto, Masato Kajikawa, Yukihito Higashi   +5 more
doaj   +1 more source