Results 41 to 50 of about 424,495 (312)

Temporal Dynamics and Heterogeneity of Cell Populations during Skeletal Muscle Regeneration

open access: yesiScience, 2020
Summary: Mammalian skeletal muscle possesses a unique ability to regenerate, which is primarily mediated by a population of resident muscle stem cells (MuSCs) and requires a concerted response from other supporting cell populations.
Stephanie N. Oprescu   +4 more
doaj   +1 more source

Monocyte-derived Kupffer cells dominate in the Kupffer cell pool during liver injury

open access: yesCell Reports, 2023
Summary: Healthy Kupffer cell (KC) pool is dominated by embryonic KCs (EmKCs), preserving liver homeostasis. How the KC pool varies upon injury remains unclear.
Weiyang Li   +4 more
doaj   +1 more source

Regeneration of begonia plantlets by direct organogenesis [PDF]

open access: yes, 2009
The economic importance of ornamentals worldwide suggests a bright future for ornamental breeding. Rapid progress in plant molecular biology has great potentials to contribute to the breeding of novel ornamental plants utilizing recombinant DNA ...
Curuk, P.   +6 more
core  

Specific lid-base contacts in the 26s proteasome control the conformational switching required for substrate degradation. [PDF]

open access: yes, 2019
The 26S proteasome is essential for proteostasis and the regulation of vital processes through ATP-dependent degradation of ubiquitinated substrates. To accomplish the multi-step degradation process, the proteasomes regulatory particle, consisting of lid
Aufderheide   +42 more
core   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

open access: yesFEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil   +5 more
wiley   +1 more source

Chemically-induced photoreceptor degeneration and protection in mouse iPSC-derived three-dimensional retinal organoids

open access: yesStem Cell Research, 2017
Induced pluripotent stem cells (iPSCs), which can be differentiated into various tissues and cell types, have been used for clinical research and disease modeling.
Shin-ichiro Ito   +2 more
doaj   +1 more source

Organismic Supercategories: III. Qualitative Dynamics of Systems [PDF]

open access: yes, 1971
The representation of biological systems by means of organismic supercategories, developed in previous papers, is further discussed. The different approaches to relational biology, developed by Rashevsky, Rosen and by Baianu and Marinescu, are compared ...
Baianu, Prof. Dr. I.C.
core  

Intestinal stem cell proliferation and epithelial homeostasis in the adult Drosophila midgut [PDF]

open access: yes, 2015
Adult tissue homeostasis requires a tight balance between the removal of old or damaged cells and the production of new ones. Such processes are usually driven by dedicated stem cells that reside within specific tissue locations or niches.
Carroll, Lynsey   +2 more
core   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Plants regenerated from tissue culture contain stable epigenome changes in rice. [PDF]

open access: yes, 2013
Most transgenic crops are produced through tissue culture. The impact of utilizing such methods on the plant epigenome is poorly understood. Here we generated whole-genome, single-nucleotide resolution maps of DNA methylation in several regenerated rice ...
Bellizzi, Maria   +8 more
core   +2 more sources

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