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Versatile CRISPR‐Cas Tools for Gene Regulation in Zebrafish via an Enhanced Q Binary System

open access: yesAdvanced Science, EarlyView.
This study introduces CRISPR‐Q, a transgenic CRISPR‐Cas system leveraging the QFvpr/QUAS binary expression platform in zebrafish. CRISPR‐Q overcomes previous challenges in achieving stable and efficient gene regulation. By enabling precise spatiotemporal control of transcript knockdown (CRISPR‐QKD) and gene activation (CRISPR‐Qa), it provides a ...
Miaoyuan Shi   +13 more
wiley   +1 more source

Neurodegeneration as Ecosystem Failure: A New Paradigm for Prevention and Treatment. [PDF]

open access: yesInt J Mol Sci
Velikic G   +6 more
europepmc   +1 more source

Unlocking ultrafast hot hole transport in transition metal oxides governed by the nature of optical transitions. [PDF]

open access: yesNat Commun
Li K   +10 more
europepmc   +1 more source

Pyridinium- and bromine-substituted distyryl-BODIPY dyes for mitochondria-targeted photodynamic therapy. [PDF]

open access: yesSci Rep
Kim C   +11 more
europepmc   +1 more source
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Yb:GdCOB regenerative amplifier

Technical Digest. Summaries of papers presented at the Conference on Lasers and Electro-Optics. Postconference Technical Digest (IEEE Cat. No.01CH37170), 2001
Summary form only given. In this summary, we present the first Yb:GdCOB regenerative chirped pulse amplification system to produce 12-mJ, and 350-fs pulses. We have extracted reasonable amount of energy from Yb:GdCOB. If we employ a diode-pumping scheme, we could obtain hundreds, of milli-joule pulses with high repetition rate.
S. Bahk   +10 more
openaire   +2 more sources

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