Results 101 to 110 of about 1,644 (225)
DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu +6 more
wiley +1 more source
Oxysterols in Cancer: From Biosynthesis and Pathophysiology to Targeted Therapeutics
Mechanisms by which oxysterol targeting may enhance immunotherapy efficacy. This figure illustrates potential metabolic interventions that may improve antitumor immunity by modulating oxysterol related pathways. CH25H modulation may reduce 25‐HC accumulation, promote the conversion of cold tumors into hot tumors, and increase T cell infiltration and PD‐
Haili Shang, Yongsheng Li
wiley +1 more source
Integrated routing of heavy electrical and diesel trucks in forest transports
Abstract Fossil‐free forestry transports are important to reach climate goals. In Sweden, road transports account for around 50% of the industry's CO2 emissions and almost 20% of the road freight volumes. Previous studies have shown that electrification is a cost‐effective way for carbon abatement, while at the same time the requirements for ...
Mikael Rönnqvist +4 more
wiley +1 more source
ABSTRACT The peripheral nervous system (PNS) is responsible for innervating all regions of the body outside of the central nervous system (CNS), the latter consisting of the brain, spinal cord, and optic nerves. While myelin is an essential component for the efficient functioning of both CNS and peripheral nerve cells, it is particularly important for ...
Kathleen Margaret Hagen +1 more
wiley +1 more source
Vehicle Deceleration Prediction Model to Reflect Individual Driver Characteristics by Online Parameter Learning for Autonomous Regenerative Braking of Electric Vehicles. [PDF]
Min K, Sim G, Ahn S, Sunwoo M, Jo K.
europepmc +1 more source
Lung Pericytes: Molecular Mechanisms, Signaling Pathways, and Roles in Pulmonary Diseases
Central role of pericytes across major pulmonary diseases. Conceptual wheel diagram illustrating the central role of lung pericytes across diverse pulmonary disease states. A pericyte positioned at the center expresses canonical markers, including PDGFRβ, CD146, and NG2, and connects radially to five major disease contexts.
Stuti Agarwal +2 more
wiley +1 more source
Research on Flywheel Energy Storage Device of Regenerative Brake for Metro Vehicles
Due to the operation characteristics of short distance between stations, start acceleration and brake deceleration frequently and the huge energy generated by regenerative braking for the metro vehicles can be absorbed and stored by flywheel energy ...
Zhikun YOU, Qun ZHOU, Wei WANG
doaj
Deceleration Planning Algorithm Based on Classified Multi-Layer Perceptron Models for Smart Regenerative Braking of EV in Diverse Deceleration Conditions. [PDF]
Sim G, Min K, Ahn S, Sunwoo M, Jo K.
europepmc +1 more source
Analysis of ~1000 adults shows cytokine gene variants are more strongly associated with hematological and metabolic traits than fitness classification. IL6 and TNF‐α variants link to iron status and aerobic fitness, with exploratory multi‐locus effects involving IL15. ABSTRACT Genetic variation in cytokine genes may influence cytokine‐related signaling,
Kinga Humińska‐Lisowska +6 more
wiley +1 more source

