Results 91 to 100 of about 1,644 (225)

The Emerging Role of UCHL1 in Neurological and Musculoskeletal Diseases

Immunology &Cell Biology, EarlyView.
UCHL1‐associated pathology. The pathological role of UCHL1 in multisystem diseases, including cancer, neurological, musculoskeletal and cardiovascular disorders. ABSTRACT Ubiquitin C‐terminal hydrolase L1 (UCHL1) is a highly conserved deubiquitinating enzyme that has transitioned from being viewed as a “brain‐specific” protein to a global regulator of ...
Ru Feng, Xiu Zhong, Jianjun Li, Adrian A. Achuthan   +3 more
wiley   +1 more source

Putting the brakes on muscle growth: Myostatin as regulator of disuse atrophy

Experimental Physiology, EarlyView.
Abstract Skeletal muscle is a highly plastic tissue that rapidly adapts to changes in mechanical loading and metabolic activity. Periods of inactivity, including bed rest, limb immobilization or microgravity, induce a pronounced loss of muscle mass and function.
Derk H. C. Nieuwenhuijsen, Moritz Eggelbusch, Rob C. I. Wüst   +2 more
wiley   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

Braking Force Coordination Control for In-Wheel Motor Drive Electric Vehicles with Electro-Hydraulic Composite Braking System

Vehicles
This paper presents a coordinated control strategy for an electro-hydraulic composite braking system in in-wheel motor electric vehicles to enhance regenerative energy recovery and braking safety.
Huichen Li, Liqiang Jin, Jianhua Li, Feng Xiao, Zhongshu Wang, Guangming Zhang   +5 more
doaj   +1 more source

The Astrocyte Clock Controls Circadian Perineuronal Net Remodeling, Synapse Strength and Learning Behavior

Glia, Volume 74, Issue 10, October 2026.
Bmal1 regulates astrocyte extracellular matrix (ECM) gene expression. Bmal1 deletion in astrocytes disrupts normal circadian rhythms in perineuronal nets (PNN) and reduces PNN content in the hippocampus. In parallel with loss of PNNs, deletion of the core circadian clock gene Bmal1 in astrocytes alters behavior and synaptic function in vivo.
Philip C. Smith, Elsa I. Quillin, Katheryn B. Lefton, Celia A. McKee, Brendan Dang, Thomas Papouin, Erik S. Musiek   +6 more
wiley   +1 more source

Review of Research on Regenerative Braking Control Strategy of New Energy Vehicle

Jixie chuandong, 2020
Aiming at the regenerative braking control problem of new energy vehicles， four basic regenerative braking control strategies， fuzzy control strategies， neural network control strategies， and the research status of comprehensive optimization control ...
Fei Xie, Yongfa Qin
doaj  

Guest Editorial: Computational Intelligence in Dynamic and Uncertain Environments

CAAI Transactions on Intelligence Technology, EarlyView.
Shouyong Jiang
wiley   +1 more source

Does Test Duration Matter? Comparing 1‐s and 5‐s Isometric Mid‐Thigh Pull Protocols for Performance Diagnostics in Basketball Players

European Journal of Sport Science, Volume 26, Issue 9, September 2026.
ABSTRACT To compare kinetic characteristics of a 1‐s isometric mid‐thigh pull (IMTP) protocol with the traditional 5‐s protocol and examine their associations with basketball‐specific performance. Twenty‐five Tier 3 male basketball players performed standardized 1‐s and 5‐s IMTP trials.
Sumeng Xu, Hailong Yu, Tian Huang, Chuanzhi Wang, Longyan Yi, Bing Yan, Sulin Cheng, Xiuqiang Wang, Yang Wang, Olivier Girard   +9 more
wiley   +1 more source

Analysis of Regenerative Braking Failure for Locomotive Induced by Grid Power Quality

Kongzhi Yu Xinxi Jishu, 2016
Aiming at the phenomenon that regenerative braking failure occurs frequently in some electric locomotives of electrified railway in China, it validated that grid power quality is one of the important factors which cause the regenerative braking failure ...
HUANG Wenxun, GONG Yansheng, JIANG Gonglian, CHEN Minwu   +3 more
doaj  

Advances in FGF/FGFR Signaling: Implications for Disease and Therapy

MedComm, Volume 7, Issue 9, September 2026.
The FGF/FGFR signaling is indispensable for the maintenance of physiological homeostasis and governs multiple biological processes, including embryonic development, bone metabolism, angiogenesis, and neurogenesis, whereas aberrant hyperactivation of this pathway drives the progression of malignancies and autoimmune disorders, including inflammatory ...
Miaoyu Song, Xi Liu, Yang Xiao, Yongsheng Li, Huakan Zhao   +4 more
wiley   +1 more source