Results 131 to 140 of about 3,412 (242)

SIRT Family: Biological Functions and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang, Feng‐Li Jiang, Fang‐Yuan Zhang, Dong‐Hui Huang, Xiao‐Ying Li, Song Gao, Hua You, Qi‐Jun Wu, Huan‐Huan Chen, Ting‐Ting Gong   +9 more
wiley   +1 more source

Metabolic Regulation of Macrophages in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Extracellular metabolites drive metabolic rewiring of glucose, lipid, and amino acid pathways in macrophages, steering their polarization toward pro‐ or anti‐inflammatory phenotypes and shaping a wide range of disease processes. Macrophages from different tissues display distinct metabolic signatures, and therapeutic strategies that target these ...
Shan Huang, Yu Zhang, Jiali Min, Jiahui Yang, Yuchen Li, Hao Zhang, Shanshan Liu   +6 more
wiley   +1 more source

Maximization of Regenerative Braking Effectivity [PDF]

, 2015
Tato diplomová práce navazuje na předchozí bakalářskou práci z roku 2010 viz [ 1 ], která se zabývala rekuperačním spádovým brzděním. Rozšiřuje analýzu o možnost využití rekuperačního brzdění zastavovacího na elektrizovaných tratích v ČR.
Lednický Denis
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Nucleotide Metabolism in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Nucleotide metabolism, including de novo synthesis, salvage pathways, and catabolism, when dysregulated contributes to cancer, immune disorders, metabolic and urological diseases, and radiation injury. Metabolites such as adenosine, cGAMP, NAD, and cAMP and enzymes like RNR are promising therapeutic targets and biomarkers.
Xiaoying Zhao, Yiyu Zeng, Yike Xu, Shu Rao, Mouna Khouchani, Hassna Soummane, Jingyi Li, Rui Liu   +7 more
wiley   +1 more source

Overvoltage Avoidance Control Strategy for Braking Process of Brushless DC Motor Drives with Small DC-Link Capacitance

Actuators
Single-phase input rectifier brushless DC motor drives with a small film capacitor have many advantages, such as high power density and high reliability.
Wei Chen, Jialong Wu, Xinmin Li, Chen Li
doaj   +1 more source

Flywheel Energy Storage with Mechanical Input-Output for Regenerative Braking

Modern Mechanical Engineering, 2014
The system presented in this paper allows the direct transfer of kinetic energy of a vehicle’s motion to a flywheel and vice-versa. For braking, a cable winds onto a pulley geared to the vehicle’s propulsion driveshaft as it unwinds from another pulley geared to the flywheel and then operates in reverse for the transfer of energy in the opposite ...
openaire   +2 more sources

Tertiary‐Ozone‐Maximum‐Like Mesospheric Ozone Increases Driven by Solar Eclipses: Sensitivity Experiments on WACCM‐X

Journal of Geophysical Research: Space Physics, Volume 131, Issue 8, August 2026.
Abstract Solar eclipses offer natural experiments to isolate the photochemical response of mesospheric ozone to solar radiation. Using the WACCM‐X model, we performed mechanism‐oriented sensitivity experiments for the 14 December 2020 eclipse to quantify the tertiary‐ozone‐maximum‐like (TOM‐like) response.
T. Yang, T. Nagahama, A. Mizuno, T. Dang, J. Lei, Joseph M. McInerney   +5 more
wiley   +1 more source

Research on sychronverter-based regenerative braking energy feedback system of urban rail trains. [PDF]

, 2019
A large amount of regenerative braking energy, caused by frequent braking of urban rail trains, has not been effectively utilized. For this problem, a regenerative braking energy feedback system of urban rail trains, using the sychronverter, is ...
Wu, Songrong, Univeristy, Southwest, Li, Shuting, He, Shengzhong   +3 more
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The Divergent Effects of Nicotinamide Riboside and High‐Intensity Exercise Training on Skeletal Muscle Epigenetic Aging

Aging Cell, Volume 25, Issue 8, August 2026.
This study investigated the effects of nicotinamide riboside supplementation and high‐intensity interval training on skeletal muscle epigenetic aging. Our findings reveal that both interventions may modify epigenetic aging, with the muscle‐specific MEAT and DunedinPACE clocks showing the most responsiveness and links to mitochondrial abundance ...
Aino Heikkinen, Liina Uusitalo‐Kylmälä, Ida Blom, Jørn Wulff Helge, Linn Gillberg, Robert Seaborne, Steen Larsen, Macsue Jacques, Robin Grolaux, Sari Aaltonen, Jaakko Kaprio, Birgitta W. van der Kolk, Sini Heinonen, Nir Eynon, Kirsi H. Pietiläinen, Riikka Kivelä, Eija Pirinen, Miina Ollikainen   +17 more
wiley   +1 more source

REGENERATIVE BRAKING SYSTEM USING SUPER CAPACITOR [PDF]

, 2011
Recently, a lot of people are concern on the environmental pollution that is getting worse day to day and energy crisis that would implicate to the global economy.
Mohamad Hanafiah, Mohammad Muzakkir
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