Results 121 to 130 of about 4,954 (273)

An Updated Classification of Hydraulic Cements Used in Dentistry

International Endodontic Journal, EarlyView.
ABSTRACT Mineral trioxide aggregate (MTA) was the first hydraulic cement used in endodontics. It is composed of Portland cement, a binder in concrete, and bismuth oxide to enhance the radiopacity. MTA was introduced in dentistry to be used as a root‐end filling material and also to repair root perforations.
Josette Camilleri
wiley   +1 more source

The Effects of Intracanal Irrigants and Medicaments on Dental-Derived Stem Cells Fate in Regenerative Endodontics: An update.

, 2020
Regenerative endodontics is a biologically based treatment designed for immature permanent teeth with necrotic pulp to replace dentin and root structures, as well as dental pulp cells.
Cheayto, Ali, Najar, Mehdi, Ayoub, Sara, Bassam, Sanaa, Berbéri, Antoine, Fayyad Kazan, Mohammad   +5 more
core   +1 more source

Optimal Hypoxia Mimetic Small Molecules for Enhancing Angiogenic Properties of Stem Cells From Human Exfoliated Deciduous Teeth

International Endodontic Journal, EarlyView.
ABSTRACT Aim Hypoxic preconditioning of cells holds promise for regenerative therapies, yet identifying effective and safe methods for clinical application remains challenging. We aimed to determine optimal hypoxia‐mimetic small molecules (SMs) that stabilize hypoxia‐inducible factor‐1α (HIF‐1α) and their dosages for hypoxic preconditioning in stem ...
Hong Wang, Jiawei Liu, Xintao Yang, Mohamad Koohi‐Moghadam, Shuting Gao, Yuanyuan Han, Dineshi Sewvandi Thalakiriyawa, James Kit Hon Tsoi, Yanqi Yang, Waruna Lakmal Dissanayaka   +9 more
wiley   +1 more source

Endodontic microsurgery for failed regenerative endodontic procedures

Asian Journal of Surgery, 2023
Nan Wang, He Liu, Ya Shen
openaire   +3 more sources

The Role of Neuropeptide Y in Dental Pulp: Balancing Neurogenic Inflammation and Pain Modulation

International Endodontic Journal, EarlyView.
ABSTRACT Background Dental pulp is a densely innervated, low‐compliance tissue in which neurogenic inflammation can rapidly escalate into oedema, raised intrapulpal pressure, microvascular compromise, and pain. While Substance P (SP) and Calcitonin gene‐related peptide (CGRP) are well‐established drivers of pulp vasodilation, the Neuroopeptide Y (NPY ...
Javier Caviedes‐Bucheli, Esteban Ulate, Hugo‐Roberto Munoz, Nestor Ríos‐Osorio   +3 more
wiley   +1 more source

The Interplay of M1 Macrophages and Dental Pulp Stem Cells Promotes Angiogenesis Through IL‐8‐Dependent VEGF Regulation: An In Vitro Study

International Endodontic Journal, EarlyView.
ABSTRACT Background Dental pulp inflammation triggers immune responses involving macrophages and dental pulp stem cells (DPSCs), which interact to regulate angiogenesis essential for tissue repair. M1 pro‐inflammatory macrophages predominate early in pulpitis, and clarifying their angiogenic role is vital in identifying inflammatory regenerative ...
Dineshi Sewvandi Thalakiriyawa, Mohamad Koohi‐Moghadam, Mingxin Hu, Hong Wang, Colman McGrath, Waruna Lakmal Dissanayaka   +5 more
wiley   +1 more source

Distinct Microbiota and Functional Pathway Profiles Define Success and Failure in Regenerative Endodontic Treatment

International Endodontic Journal, EarlyView.
ABSTRACT Aim To characterize the intracanal microbiota and identify key microbial taxa and functional pathways associated with regenerative endodontic treatment (RET) outcomes. Methodology In this observational cohort study, 196 samples were collected at five time points from external tooth surfaces (T1, T4) and root canals (T2, T3, T5).
Leimarembi Devi Naorem, Alina Wikström, Peter Quach, Lokeshwaran Manoharan, Ronald Ordinola‐Zapata, Olena Rakhimova, Malin Brundin, Nelly Romani Vestman   +7 more
wiley   +1 more source

Enamel Matrix Derivative in Dental Pulp Regeneration: Biological Basis, Mechanistic Insights, and Translational Considerations

Stem Cells International
Enamel matrix derivative (EMD) has attracted increasing attention in regenerative endodontics because of its potential to influence multiple biological processes involved in dental pulp healing.
LinLin Zhang, KaiLiang Tang, XinYu Zhao, Yi Du   +3 more
doaj   +1 more source

Regenerative endodontics: A review

International Dental Research
Oral health and function are critical components of a patient's overall quality of life. Pulp necrosis in immature permanent teeth, resulting from trauma, caries, or developmental anomalies, presents a significant clinical challenge. Traditionally, apexification has been the routine treatment; however, it fails to promote continued root development ...
Tolga Han Edebal, Gülşen Edebal
openaire   +1 more source

Cellular Dynamics and Dentine Bridge Formation Following Direct Pulp Capping With MTA and Biodentine in a Murine Model

International Endodontic Journal, EarlyView.
ABSTRACT Aim Formation of a mineralized dentine bridge is the hallmark of successful direct pulp capping (DPC). Mineral trioxide aggregate (MTA) and Biodentine are widely used capping materials, but in vivo evidence comparing their regenerative potential remains inconclusive. This study used a controlled murine model to compare dentine bridge formation
Amnah Sajdeya, Joshua Milgram, Nurit Kot‐Limon, Itzhak Abramovitz, Amnon Sharir   +4 more
wiley   +1 more source