Wharton's jelly mesenchymal stem cell-derived exosomes promote odontogenic differentiation of dental pulp stem cells: A cell-free strategy for regenerative endodontics. [PDF]
Ricardo S +5 more
europepmc +1 more source
ABSTRACT Aim The aim of this study was to compare the accuracy and inter‐account consistency of two Google Gemini–powered, user‐facing workflows for dental trauma decision support: standalone Gemini chat and NotebookLM, a document‐grounded workflow that generates responses grounded in uploaded European Society of Endodontology and International ...
Nicolás Dufey‐Portilla +7 more
wiley +1 more source
Enterococcus faecalis biofilm removal efficacy, cytotoxicity and alkaline phosphatase activity on stem cells after the application of conventional medicaments and novel hydrogels used in regenerative endodontics. [PDF]
Öztürk A, Duran T, Eldeniz AU.
europepmc +1 more source
ABSTRACT Aim Hypoxic preconditioning of cells holds promise for regenerative therapies, yet identifying effective and safe methods for clinical application remains challenging. We aimed to determine optimal hypoxia‐mimetic small molecules (SMs) that stabilize hypoxia‐inducible factor‐1α (HIF‐1α) and their dosages for hypoxic preconditioning in stem ...
Hong Wang +9 more
wiley +1 more source
An In Vitro Tube Model for Cell Biocompatibility Study of Capping Materials for Regenerative Endodontics. [PDF]
Pilbauerova N +3 more
europepmc +1 more source
The Role of Neuropeptide Y in Dental Pulp: Balancing Neurogenic Inflammation and Pain Modulation
ABSTRACT Background Dental pulp is a densely innervated, low‐compliance tissue in which neurogenic inflammation can rapidly escalate into oedema, raised intrapulpal pressure, microvascular compromise, and pain. While Substance P (SP) and Calcitonin gene‐related peptide (CGRP) are well‐established drivers of pulp vasodilation, the Neuroopeptide Y (NPY ...
Javier Caviedes‐Bucheli +3 more
wiley +1 more source
Comparative outcomes and success rates of regenerative endodontics versus traditional root canal therapy: A systematic review and meta-analysis. [PDF]
Mujawar A +7 more
europepmc +1 more source
ABSTRACT Background Dental pulp inflammation triggers immune responses involving macrophages and dental pulp stem cells (DPSCs), which interact to regulate angiogenesis essential for tissue repair. M1 pro‐inflammatory macrophages predominate early in pulpitis, and clarifying their angiogenic role is vital in identifying inflammatory regenerative ...
Dineshi Sewvandi Thalakiriyawa +5 more
wiley +1 more source
Stress in Immature Incisor Treated With Regenerative Endodontics or Restored With Bulk-Fill Resin Composite: A 2D Finite Element Analysis. [PDF]
de Souza GL +6 more
europepmc +1 more source
ABSTRACT Aim To characterize the intracanal microbiota and identify key microbial taxa and functional pathways associated with regenerative endodontic treatment (RET) outcomes. Methodology In this observational cohort study, 196 samples were collected at five time points from external tooth surfaces (T1, T4) and root canals (T2, T3, T5).
Leimarembi Devi Naorem +7 more
wiley +1 more source

