Results 161 to 170 of about 4,234 (232)

Towards a New Concept of Regenerative Endodontics Based on Mesenchymal Stem Cell-Derived Secretomes Products. [PDF]

Bioengineering (Basel), 2022
Costa LA, Eiro N, Vaca A, Vizoso FJ.
europepmc   +1 more source

Shikonin promotes osteogenic differentiation of periodontal ligament stem cells by modulating the p38 MAPK/ETS transcription factor 1/cementum protein 1 axis in vitro

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
Our study revealed that Shikonin enhanced osteogenic differentiation by promoting the ELK1/CEMP1 axis via the activation of p38 MAPK signaling in PDLSCs. This indicated that Shikonin may serve as a candidate drug, while the ELK1/CEMP1 axis may be identified as a valuable pathway for promoting the osteogenic differentiation of PDLSCs.
Zeyu Wu, Chao Shan, Jie Song, Qian Yu, Bing‐jie Lian, Jin Zhao   +5 more
wiley   +1 more source

Wharton's jelly mesenchymal stem cell-derived exosomes promote odontogenic differentiation of dental pulp stem cells: A cell-free strategy for regenerative endodontics. [PDF]

J Conserv Dent Endod
Ricardo S, Kamano Y, Saito M, Bagio DA, Julianto I, Margono A.   +5 more
europepmc   +1 more source

Development of a Nano‐Hybrid Composite Using Bovine Hydroxyapatite and Montmorillonite for Endodontic Applications—An In Vitro Study

International Endodontic Journal, Volume 59, Issue 9, Page 1936-1953, September 2026.
ABSTRACT Aim Hydraulic calcium silicate cements are widely employed in endodontics due to their excellent biocompatibility, bioactivity, sealing ability, and remineralisation potential. However, currently used products such as mineral trioxide aggregate (MTA) exhibit several limitations, including discolouration, cost, and poor handling properties ...
P. A. A. S. Prasad Kumara, Paul R. Cooper, Peter Cathro, Henry F. Duncan, Maree Gould, George Dias, Jithendra Ratnayake   +6 more
wiley   +1 more source

An In Vitro Tube Model for Cell Biocompatibility Study of Capping Materials for Regenerative Endodontics. [PDF]

J Endod
Pilbauerova N, Dasi D, de Souza Araujo IJ, Huang GT.   +3 more
europepmc   +1 more source

Dentine Regeneration With Calcium Strontium Silicate: In Vitro Odontogenic Differentiation, Antimicrobial Activity, Immunomodulation and In Vivo Pulpotomy in Rat Molars

International Endodontic Journal, Volume 59, Issue 9, Page 1871-1886, September 2026.
ABSTRACT Aim This study examined the in vitro and in vivo performance of calcium strontium silicate (CSR) as a novel biomaterial for vital pulp therapy (VPT), assessing its odontogenic differentiation, antibacterial activity, immunomodulation, inflammatory response and dentine regeneration potential compared to calcium silicate (CS) and Mineral ...
Mohamed Mahmoud Abdalla, Vidhyashree Rajasekar, Heba Ahmed, Mengyu Huang, Cynthia Kar Yung Yiu   +4 more
wiley   +1 more source

Comparative outcomes and success rates of regenerative endodontics versus traditional root canal therapy: A systematic review and meta-analysis. [PDF]

J Int Med Res
Mujawar A, Pandit V, Shaikh S, Shaikh B, Alessa NA, Kader MA, Alqarni M, Karobari MI.   +7 more
europepmc   +1 more source

Inflammation‐Regeneration Axis of Dental Pulp Stem Cells: Wnt/NF‐κB Crosstalk

International Endodontic Journal, Volume 59, Issue 9, Page 1743-1759, September 2026.
ABSTRACT Background Inflammation critically determines dental pulp regenerative outcomes, with dental pulp stem cells (DPSCs) orchestrating tissue homeostasis through differentiation, self‐renewal and immunomodulation processes dynamically regulated by Wnt/β‐catenin and NF‐κB signaling crosstalk.
V. Rajasekar, M. Huang, M. M. Abdalla, P. Neelakantan, C. K. Y. Yiu   +4 more
wiley   +1 more source

Stress in Immature Incisor Treated With Regenerative Endodontics or Restored With Bulk-Fill Resin Composite: A 2D Finite Element Analysis. [PDF]

Aust Endod J
de Souza GL, de Bragança GF, Vilela ABF, Rondón AKA, Kahler B, Soares CJ, Moura CCG.   +6 more
europepmc   +1 more source

Outcomes of Root Canal Treatment in Patients With Autoimmune Disease: A Retrospective Case–Control Study

International Endodontic Journal, Volume 59, Issue 9, Page 1831-1840, September 2026.
ABSTRACT Aim The purpose of this study was to compare the outcome of nonsurgical root canal treatment (RCT) in patients with autoimmune diseases (AD) with the outcome in patients without AD. The null hypothesis was: there is no difference in the outcomes of RCT regardless of the patient group. Results were also compared among AD subgroups: inflammatory
Seoyeon Lee, Euiseong Kim, Hoiin Jung, Hyejin Kim, Sunil Kim   +4 more
wiley   +1 more source