Results 91 to 100 of about 932,294 (385)

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Review of Investigation on Regenerator for Regenerative Cryocoolers

open access: yesZhileng xuebao, 2011
Regenerator is a key part of regenerative cryocoolers,and it gives predominant contribution to the performance of cryocoolers.In this paper,the recent development of regenerator in regenerative cryocoolers is described.Stacked mesh screens,parallel wires,
doaj   +2 more sources

Methodology of heat transfer and flow resistance measurement for matrices of rotating regenerative heat exchangers

open access: yesChemical and Process Engineering, 2016
The theoretical basis for the indirect measurement approach of mean heat transfer coefficient for the packed bed based on the modified single blow technique was presented and discussed in the paper.
Butrymowicz Dariusz   +7 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini   +13 more
wiley   +1 more source

Preliminary experimental comparison and feasibility analysis of CO2/R134a mixture in Organic Rankine Cycle for waste heat recovery from diesel engines [PDF]

open access: yes, 2019
This paper presents results of a preliminary experimental study of the Organic Rankine Cycle (ORC) using CO2/R134a mixture based on an expansion valve.
Feng, W   +5 more
core  

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen   +18 more
wiley   +1 more source

Efficient Greedy Randomized Adaptive Search Procedure for the Generalized Regenerator Location Problem

open access: yesInternational Journal of Computational Intelligence Systems, 2016
Over the years, there has been an evolution in the manner in which we perform traditional tasks. Nowadays, almost every simple action that we can think about involves the connection among two or more devices.
J.D. Quintana   +2 more
doaj   +1 more source

Histological Evaluation of Bone Regeneration Using Hydroxyapatite Based Bone Substitute Derived from Antler: An Animal Study [PDF]

open access: bronze, 2021
Naser Sargolzaie   +6 more
openalex   +1 more source

Daratumumab Treatment for Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP): A Case Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an immune‐mediated neuropathy featuring progressive weakness, sensory deficits, and areflexia. While corticosteroids, intravenous immunoglobulin, and plasmapheresis are effective first‐line immunotherapies, a subset of patients remains treatment‐refractory.
Xueyu Zhang   +8 more
wiley   +1 more source

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