Results 41 to 50 of about 5,049,311 (291)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
[Trofeo Región 1974] [Material gráfico]
, 1974 Ninguna de las fotos indica autoríaContiene fotografías pertenecientes al archivo fotográfico del diario "Región", publicadas hacia ...
Diario Región (Oviedo)
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Revista Peruana de Medicina Experimental y Salud Pública, 2004 Objetivo: Evaluar la concordancia de los resultados obtenidos por promotores de salud de áreas rurales de la Amazonia peruana con los obtenidos por profesionales de laboratorio, al aplicar una prueba rápida inmunocromatográfica para el diagnóstico de la ...
César Cabezas S +8 more
doaj
Clinical Case Reports, 2020 Performing a supplementation intervention with creatine and protein, in conjunction with low‐intensity endurance and resistance exercise is safe and has a positive effect on the quality of life in a patient with desminopathy.
Camila Monje +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
[Trofeo Región 1976] [Material gráfico]
, 1976 Ninguna de las fotos indica autoríaContiene fotografías pertenecientes al archivo fotográfico del diario "Región", publicadas hacia ...
Diario Región (Oviedo)
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
[Trofeo Región] [Material gráfico]
, 1967 Algunas fotos no indican autoría; el resto firmadas por Foto Sierra (Oviedo)Contiene fotografías pertenecientes al archivo fotográfico del diario "Región", publicadas entre 1967 y ...
Diario Región (Oviedo) +1 more
core