Results 91 to 100 of about 1,252,806 (307)
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Regime-Switching Stochastic Volatility and Short-Term Interest Rates. [PDF]
In this paper, we introduce regime-switching in a two-factor stochastic volatility model to explain the behavior of short-term interest rates. The regime-switching stochastic volatility (RSV) process for interest rates is able to capture all possible ...
Raúl Susmel, Madhu Kalimipalli
core
The article presents the results of a comparative analysis of Margaret Atwood’s The Handmaid’s Tale and essays written by Herta Müller, the most famous Romanian dissident and the recipient of the 2009 Noble Prize in literature.
Ewelina Feldman-Kołodziejuk
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Regime Switching and Artificial Neural Network Forecasting [PDF]
This paper provides an analysis of regime switching in volatility and out-of-sample forecasting of the Cyprus Stock Exchange using daily data for the period 1996-2002.
Robert Georgiades +3 more
core
Geomorphological insight into changing tectonic regime, Pasinler Basin, Turkey [PDF]
The Pasinler Basin, in the East Anatolian Contractional Province, features a suite of geomorphological zones, visible in the field, air photographs and Landsat and SRTM DEM imagery. These zones reflect past and current tectonically influenced processes.
Rust, DJ +5 more
core +1 more source
The Muslim Brotherhood: ¿A centrifugal or centripetal force?
Before the third Egyptian revolution in early 2011, the Muslim Brotherhood was considered the only real opposition capable of challenging the hegemonic government of the Egyptian regime, owing to the popular support the organisation enjoyed; much greater
Athina Lampridi-Kemou
doaj
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Constitucionalidade e análise crítica da contratação integrada prevista pelo Regime Diferenciado de Contratações Pública - RDC [PDF]
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Jurídicas. Direito.A presente monografia tem por objeto analisar a constitucionalidade e as críticas ao regime de execução da contratação integrada prevista pelo Regime ...
Garcia, Daniel Piccoli
core
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source

