Results 101 to 110 of about 1,252,806 (307)

Regime switching GARCH models [PDF]

open access: yes
We develop univariate regime-switching GARCH (RS-GARCH) models wherein the conditional variance switches in time from one GARCH process to another. The switching is governed by a time-varying probability, specified as a function of past information.
Luc, BAUWENS   +2 more
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Asset allocation under multivariate regime switching [PDF]

open access: yes
This paper studies asset allocation decisions in the presence of regime switching in asset returns. We find evidence that four separate regimes - characterized as crash, slow growth, bull and recovery states - are required to capture the joint ...
Massimo Guidolin, Allan Timmerman
core  

EUAs and CERs : Interactions in a Markov regime-switching environment. [PDF]

open access: yes
This paper analyzes jointly the time series of European Union Allowances (EUAs) and Certified Emissions Reductions (CERs) in a Markov regime-switching environment.
Chevallier, Julien
core   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Le transizioni di regime nell'Italia dell'Ottocento

open access: yes, 2007
Analisi delle transizioni di regime dall'italia napoleonica a quella della restaurazione e dall'italia preunitaria a quella ...
MERIGGI, MARCO
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Gli ufficiali di carriera dell'Esercito nella crisi del regime

open access: yes, 1996
Atteggiamento degli ufficiali nei confronti del Regime di fronte alle scelte interne ( leggi razziali ) e di politica estera del regime, e poi dell'andamento della ...
MINNITI, FORTUNATO
core  

GOVERNMENT REGIME AND POLITICAL REGIME: ARE SYNONIMOUS OR NOT?

open access: yesAdvances in Law Studies, 2016
By this time in the domestic literature on theory of law and constitutional law were discrepancies in the definition of "political regime", "national treatment", "public-political regime." Getting to the analysis of this issue, it should be borne in mind that the concept of "political ...
openaire   +1 more source

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