Results 111 to 120 of about 1,290,184 (308)
The increasing integration of artificial intelligence technologies into the financial structures of the BRICS Plus countries (comprising the original member countries of Brazil, Russia, India, China, and South Africa as well as the four new member ...
M. Aksenova
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Goodness-of-fit testing for regime-switching models [PDF]
In this paper we propose a novel goodness-of-fit testing scheme for regime-switching models. We consider models with an observable, as well as, a latent state process.
Weron, Rafal, Janczura, Joanna
core
Making Promises Good: The Anti-Money Laundering Regime as a Multi-Purpose Tool for Governance [PDF]
The creation of this international anti-money laundering regulatory regime is, contrary to itsneglect by the literature, important in two ways. First, it provides us with a second example -alongside the Basle Accord – with which we can examine how ...
Stavros Katsios
doaj
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Constitucionalidade e análise crítica da contratação integrada prevista pelo Regime Diferenciado de Contratações Pública - RDC [PDF]
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Jurídicas. Direito.A presente monografia tem por objeto analisar a constitucionalidade e as críticas ao regime de execução da contratação integrada prevista pelo Regime ...
Garcia, Daniel Piccoli
core
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
A two regime model of inflation and unemployment fluctuations [PDF]
In this paper we present a formal definition of the notions of economic regime and regime dynamics. Starting from these definitions, we discuss a multiple regime dynamic model generating an endogenous unemployment-price adjustment mechanism.
Juan Gabriel Brida
core
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source

