The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Back Matter Vol. 20 No.2 (2025)
Jurnal Region
doaj
Mapping antibiotic resistance in Ghana: a narrative review of regional variations in antibiotic-resistant ESKAPEE pathogens. [PDF]
Abubakari A +3 more
europepmc +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Evaluating infection prevention and control implementation in hospitals of underdeveloped region of China using the standardized WHO-IPCAF tool. [PDF]
Li L +5 more
europepmc +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Front Matter Vol. 20 No.1 (2025)
Jurnal Region
doaj
Impedance Spectroscopy Study of Solid Co(II/III) Redox Mediators Prepared with Poly(Ethylene Oxide), Succinonitrile, Cobalt Salts, and Lithium Perchlorate for Dye-Sensitized Solar Cells. [PDF]
Gupta RK +6 more
europepmc +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Correction: Association of glutamine metabolites in synovial fluid with the severity of temporomandibular joint osteoarthritis. [PDF]
Song Z, Xu Y, Li C, Shao B, Gong Z.
europepmc +1 more source

