Results 51 to 60 of about 1,135,893 (304)

Depression, Stress and Regional Cerebral Blood Flow [PDF]

, 2023
Decreased cerebral blood flow (CBF) may be an important mechanism associated with depression. In this study we aimed to determine if the association of CBF and depression is dependent on current level of depression or the tendency to experience ...
Adhikari, Bhim M, Ament, Seth, Bruce, Heather A, Chen, Shuo, Chiappelli, Joshua, Goldwaser, Eric L, Hong, L Elliot, Kochunov, Peter, Kvarta, Mark D, Ma, Yizhou, Mitchell, Braxton D, Shuldiner, Alan R, Wang, Danny Jj   +12 more
core   +1 more source

Clinical and Imaging Features of Sporadic and Genetic Frontotemporal Lobar Degeneration TDP‐43 A and B

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Certain frontotemporal lobar degeneration subtypes, including TDP‐A and B, can either occur sporadically or in association with specific genetic mutations. It is uncertain whether syndromic or imaging features previously associated with these patient groups are subtype or genotype specific.
Sean Coulborn, Rhiana Schafer, Ashlin R. K. Roy, Andrzej Sokolowski, Noah G. Cryns, Dana Leichter, Argentina Lario Lago, Eliana Marisa Ramos, Yann Cobigo, Salvatore Spina, Lea T. Grinberg, Daniel H. Geschwind, Maria L. Gorno‐Tempini, Joel H. Kramer, Howard J. Rosen, Bruce L. Miller, William W. Seeley, David C. Perry   +17 more
wiley   +1 more source

A Prospective Study to Determine the Effect of Intermittent Pneumatic Foot and Calf Compression on Popliteal Artery Peak Systolic Blood Flow

Asian Journal of Surgery, 2008
Objective: This study investigated the effects of posture and also intermittent foot and calf compression on peak systolic flow of the popliteal artery in a normal population.
Suziah Mokhtar, Zainal A. Azizi, Naresh Govindarajanthran   +2 more
doaj   +1 more source

Dual‐Phase C‐11 PiB PET Images for Detecting Tau Pathology in Cerebral Amyloid Angiopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cerebral amyloid angiopathy (CAA) is a major cause of lobar intracerebral hemorrhage and cognitive dysfunction in the elderly, and frequently coexists with Alzheimer's disease and tau pathology. Dual‐phase 11C‐PiB PET detects amyloid deposition and cerebral perfusion changes and may have diagnostic value for identifying tau in CAA ...
Meng‐Ting Chiang, Chia‐Ju Liu, Bo‐Ching Lee, Ruoh‐Fang Yen, Hsin‐Hsi Tsai   +4 more
wiley   +1 more source

A Novel CHMP2B Splicing Variant in Atypical Presentation of Familial Frontotemporal Lobar Degeneration

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT C‐truncating variants in the charged multivesicular body protein 2B (CHMP2B) gene are a rare cause of frontotemporal lobar degeneration (FTLD), previously identified only in Denmark, Belgium, and China. We report a novel CHMP2B splice‐site variant (c.35‐1G>A) associated with familial FTLD in Spain. The cases were two monozygotic male twins who
Sara Rubio‐Guerra, Sara Bernal, David Almenta, Josefina Pérez‐Blanco, Valle Camacho, Isabel Sala, Mª Belén Sánchez‐Saudinós, Jesús García Castro, Judit Selma‐González, Miguel Ángel Santos‐Santos, Álvaro Carbayo, Janina Turon‐Sans, Ricard Rojas‐Garcia, Daniel Alcolea, Juan Fortea, Alberto Lleó, Oriol Dols‐Icardo, Ignacio Illán‐Gala   +17 more
wiley   +1 more source

Perfusion of the interventricular septum during ventilation with positive end-expiratory pressure (PEEP) [PDF]

, 1991
Objective: To determine whether regional hypoperfusion of the interventricular septum occurs during ventilation with positive end-expiratory pressure. Design: Animal study. Animals: Anesthetized, closed chest dogs (n = 8).
Iber, Volker, Messmer, Konrad, Schosser, Rudolf, Schwickert, Christiane, Spengler, Peter, Weiss, Michaela, Zwißler, Bernhard   +6 more
core  

Myocardial blood flow regulation in infarcted patients with stress-induced normalization of negative T waves [PDF]

, 1997
The correlation of stress-induced normalization of negative T waves (NTW) with regional myocardial blood flow (MBF) regulation and tissue viability remains still ...
Gimelli, Alessia, Giorgetti, Assuero, Neglia, Danilo, Nista, Nicola, Parodi, Oberdan, Sambuceti, Gianmario   +5 more
core   +1 more source

Regional Cerebral Blood Flow Abnormalities in Neurosyphilis: A Pilot SPECT Study

Frontiers in Neurology, 2021
Objective: Clinical and radiological findings on neurosyphilis are fairly non-specific and there is a paucity of functional neuroimaging studies on neurosyphilis other than case reports and case series.
Jooyeon J. Im, Hyeonseok Jeong, Hyeonseok Jeong, Young Do Kim, Kyung-Sool Jang, In-Uk Song, Yong-An Chung, Yong-An Chung   +7 more
doaj   +1 more source

Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden, Charles Carron, Donatienne Van Weehaeghe, Joke De Vocht, Fouke Ombelet, Pegah Masrori, Caro De Weerdt, Rebecca E. James, Lauren T. Evans, Frederick A. Schroeder, Jacob M. Hooker, Michel Koole, Janice E. Kranz, Tonya M. Gilbert, Philip Van Damme, Koen Van Laere   +15 more
wiley   +1 more source

Modeling co-operative volume signaling in a plexus of nitric oxide synthase-expressing neurons [PDF]

, 2005
In vertebrate and invertebrate brains, nitric oxide (NO) synthase (NOS) is frequently expressed in extensive meshworks (plexuses) of exceedingly fine fibers.
Husbands, Philip, Lovick, Thelma A., O'Shea, Michael, Ott, Swidbert R., Philippides, Andrew   +4 more
core   +1 more source