Results 51 to 60 of about 616,798 (355)

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Regional cerebral blood flow and extraversion

Personality and Individual Differences, 1993
Summary-Regional cerebral blood flow (rCBF) was examined in a group of 17 subjects (8 men, 9 women, ages 22-35 years) at rest and during three mental activations, inducing perceptual and spatial processing. The subjects completed two personality questionnaires, the Eysenck Personality Inventory and the Karolinska Scales of Personality (KSP). The aim of
Stenberg, Georg, Wendt, Peter E., Risberg, Jarl   +2 more
openaire   +4 more sources

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Ocular hemodynamics in patients with rhegmatogenous retinal detachment

Zaporožskij Medicinskij Žurnal, 2014
Aim. In case of retinal detachment atrophic processes lead to irreversible loss of functions within 4–6 days, it happens on underlying low ocular blood flow.
N. H. Zavgorodnya, A. V. Dedov, Ye. M. Ivakhnenko   +2 more
doaj   +1 more source

Effect of propranolol on regional myocardial function in anesthetized open-chest dogs with myocardial ischemia [PDF]

, 1978
Effects of propranolol on ischemic segmental function were studied in anesthetized open-chest dogs. Two segment-length gauges were used for measuring the regional myocardial function: one was sutured on to the left ventricular surface perfused by the ...
Haraoka, Shoichi, Ikenaga, Toyotake, Ogino, Yasuhiro, Saito, Daiji, Tawara, Ritsuya, Ueda, Minoru, Yoshida, Hidenori, Yoshioka, Nobuhiko   +7 more
core   +1 more source

Plasma p‐tau181 as a Marker of Conversion to Alzheimer's Disease Dementia and Worsening in Cognitive Functions in Subjective Cognitive Decline and Mild Cognitive Impairment: A Longitudinal Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Plasma p‐tau181 has proven to be a promising diagnostic and prognostic tool in the earliest phases of Alzheimer's disease (AD). We aimed to evaluate the prognostic role of p‐tau181 in predicting conversion to AD dementia and worsening in cognition in mild cognitive impairment (MCI) and subjective cognitive decline (SCD).
Giulia Giacomucci, Assunta Ingannato, Chiara Crucitti, Silvia Bagnoli, Elisa Marcantelli, Sonia Padiglioni, Valentina Moschini, Carmen Morinelli, Laura Falsini, Sandro Sorbi, Valentina Berti, Benedetta Nacmias, Valentina Bessi   +12 more
wiley   +1 more source

Sex Differences in Regional Cerebral Blood Flow [PDF]

Journal of Cerebral Blood Flow & Metabolism, 1988
Regional cerebral blood flow was measured by the 133-xenon inhalation method during resting in 38 healthy men and 38 healthy women matched pairwise for age in the range 18–72 years. The results showed 11% higher global flow level in the women in all ages. A similar and significant regression of flow by age was seen for both sexes.
RODRIGUEZ, GUIDO, WARKENTIN S, RISBERG J, ROSADINI G.   +3 more
openaire   +4 more sources

Association of PET-measured myocardial flow reserve with echocardiography-estimated pulmonary artery systolic pressure in patients with hypertrophic cardiomyopathy [PDF]

, 2019
BackgroundPulmonary hypertension (PH) is a known complication of HCM and is a strong predictor of mortality. We aim to investigate the relationship between microvascular dysfunction measured by quantitative PET and PH in HCM patients.MethodsEighty-nine ...
Leal, Jeffrey P, Liu, Min, Pomper, Martin G, Tsui, Benjamin M. W., Wong, Dean F, Zhao, Min, Zhou, Yun   +6 more
core   +3 more sources

The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic, Ida Erngren, Kim Kultima, Anders Larsson, Malin Müller, Anna Wiberg, Joachim Burman   +6 more
wiley   +1 more source

Altered interictal cerebral blood flow in generalized tonic-clonic seizure: an arterial spin labeling based MRI study

Chinese Journal of Contemporary Neurology and Neurosurgery, 2011
Objective To study the alteration of interictal cerebral blood flow (CBF) of patients with generalized tonic-clonic seizure (GTCS) by pulsed arterial spin labeling (PASL), and uncover the neuropathophysiological mechanism of GTCS.
Maoxue WANG, Zhiqiang ZHANG, Guangming LU, Cuiping YUAN, Zhengge WANG, Lianfang SHEN   +5 more
doaj