Results 71 to 80 of about 7,772,715 (241)

Blood–Brain Barrier Regulation: Evolving From Classic Strategies to Electrochemical Ion and Reactive Oxygen Species Control

Advanced Healthcare Materials, EarlyView.
Conventional therapies suffer from poor blood–brain barrier (BBB) penetration and disordered ion/reactive oxygen species (ROS) homeostasis, hindering precise neurological treatment. Electrochemical strategies achieve accurate spatiotemporal regulation of neural homeostasis.
Xiaokang Hu, Caiyu Liu, Meijun Pang, Zhiyuan Shi, Dong Ming, Xiuyun Liu   +5 more
wiley   +1 more source

An Engineered Biomimetic Nanoreactor With Cascade Functions for Targeted and Combinatorial Therapy of Ischemic Stroke

Advanced Healthcare Materials, EarlyView.
Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li, Ying Wu, Huimin Wei, Jinyong Teng, Zaizhi Yang, Jufang Chen, Bao Liao, Xiaoqin Huang, Lanqing Meng, Tong Li   +9 more
wiley   +1 more source

Engineering Pluripotent Stem Cells‐Derived Inner Ear Organoids With Enhanced Maturation and Reproducibility by Micro‐Topographical Cues

Advanced Materials, EarlyView.
Micro‐topographical cues applied through temporally controlled microscale confinement improve the reproducibility, spatial organization, and neurosensory‐associated features of pluripotent stem cell‐derived inner ear organoids. Integration with a vascularized organoid platform further enables controlled investigation of vascular‐epithelial interactions
Harshita Sharma, Jungeun Lim, Woochan Kim, Yeon Ju Kim, Dream Kim, Shinyull Lee, Chaeyeon Park, Stephen Rhee, Shruthy Kuttapan, Jungho Ha, Sang Wook Park, Kyunghoon Kim, Noo Li Jeon, Sunho Park, Yun‐Hoon Choung, Jangho Kim   +15 more
wiley   +1 more source

FEATURES OF HEMODYNAMIC DISORDERS IN PATIENTS WITH TERMINAL GLAUCOMA

Офтальмохирургия, 2015
Purpose. To study features of different vascular areas of ocular hemodynamics in patients with terminal glaucoma using the ultrasound dopplerography method in a comparative aspect with the fellow eyes without diagnosed glaucoma.Material and methods.
E. V. Egorova, O. I. Fabrikantov, S. I. Nikolashin, A. A. Drobnica   +3 more
doaj  

A Prospective Study to Determine the Effect of Intermittent Pneumatic Foot and Calf Compression on Popliteal Artery Peak Systolic Blood Flow

Asian Journal of Surgery, 2008
Objective: This study investigated the effects of posture and also intermittent foot and calf compression on peak systolic flow of the popliteal artery in a normal population.
Suziah Mokhtar, Zainal A. Azizi, Naresh Govindarajanthran   +2 more
doaj   +1 more source

Artificial Intelligence Meets Micro/Nanorobotics

Advanced Materials, EarlyView.
Artificial intelligence is transforming micro‐ and nanorobots from externally controlled, task‐specific machines into adaptive, autonomous systems. Machine learning, multimodal perception, digital twins, AI‐guided materials and geometry design enhance propulsion, localization, decision‐making, whichaccelerates clinical and environmental applications ...
Fatma M. Yurtsever, Minitha Cherukutty Ramakrishnan, Ian Kuula Ross, Ivan Zelinka, Hamed Shahsavan, Michal Otyepka, Martin Pumera   +6 more
wiley   +1 more source

Human red blood cells at work: identification and visualization of erythrocytic eNOS activity in health and disease [PDF]

, 2012
A nitric oxide synthase (NOS)-like activity has been demonstrated in human red blood cells (RBCs), but doubts about its functional significance, isoform identity and disease relevance remain.
Rodriguez-Mateos, Ana; id_orcid, Wolters, Dirk, Heiß, Christian, Rodriguez Mateos, Ana, Krenz, Thomas, Kuhnle, G. G. C., Cortese-Krott, Miriam M, Rodriguez-Mateos, Ana, Kelm, Malte, Cortese-Knott, Miriam M., Feelisch, Martin, Rodriguez-Mateos, Z, Kroncke, K.-D., Kröncke, Klaus-Dietrich, Sansone, R., Kuhnle, Gunter G. C., Kelm, M., Heiss, C., Krisp, C., Sansone, Roberto, Horn, P., Feelisch, M., Horn, Patrick, Krisp, Christoph, Krenz, T., Hogg, N., Kuhnle, Gunter, Kuhnle, Gunter G.C., Thasian-Sivarajah, S., Thasian-Sivarajah, Sivatharsini, Wolters, D., Cortese-Krott, Miriam M., Hogg, Neil, Cortese-Krott, M. M.   +33 more
core   +1 more source

Characteristic of the hemostasis indices in chronic venous insufficiency in stage of decompensation

Клінічна хірургія, 2018
Objective. To compare the hemostasis indices in patients, suffering chronic venous insufficiency (CHVI) in decompensation stage, owing or not the thrombotic complications. Маterials and methods. The indices of hemostasis were studied up in 47 patients,
V. І. Rusyn, V. V. Коrsak, О. М. Коchmar, S. S. Каlynych, О. Т. Devinyak   +4 more
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Patterns of Regional Cerebral Blood Flow in Patients with Occlusive or Stenotic Lesions of Both the Internal Carotid and Vertebrobasilar Arteries [PDF]

, 1988
1988-03For the study of cerebral hemodynamics in patients with multiple occlusive or stenotic lesions of the internal carotid artery (lCA) and vertebral/basilar artery (VA/BA), six male patients (mean aged 62.5 years) were examined by regional cerebral ...
ISHIGURI, HITOSHI, ITOH, JUNKI, TAKADA, SOHSHUN, KUCHIWAKI, HIROJI   +3 more
core   +1 more source