Results 51 to 60 of about 630,334 (307)

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung, E‐nae Cheong, Jungmin So, Heung‐Won Kang, Yangsean Choi, Eun‐Jae Lee, Hyunjin Kim, Young‐Min Lim   +7 more
wiley   +1 more source

Altered Regional Cerebral Blood Flow in Chronic Whiplash Associated Disorders

EBioMedicine, 2016
There is increasing evidence of central hyperexcitability in chronic whiplash-associated disorders (cWAD). However, little is known about how an apparently simple cervical spine injury can induce changes in cerebral processes.
David Vállez García, Janine Doorduin, Antoon T.M. Willemsen, Rudi A.J.O. Dierckx, Andreas Otte   +4 more
doaj   +1 more source

Role of Ultrasound in Neurocritical Care

Journal of Neuroanaesthesiology and Critical Care, 2020
Bedside point of care ultrasound has acquired an extremely significant role in diagnosis and management of neurocritical care, just as it has in other specialties.
Rashmi Bhatt, Puneet Khanna
doaj   +1 more source

Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons, Todd Levine, Charles H. Adler, Bailey Bellaire, Ningshan Wang, Pinky Agarwal, Georgina M. Aldridge, Alexandru Barboi, Daniel Claassen, Virgilio G. H. Evidente, Douglas Galasko, Alejandra Gonzalez‐Duarte, Ramon Gil, Mark Gudesblatt, Stuart H. Isaacson, Horacio Kaufmann, Pravin Khemani, Rajeev Kumar, Guillaume Lamotte, Andy J. Liu, Nikolaus R. McFarland, Mitchell G. Miglis, Adam Reynolds, Gregory A. Sahagian, Marie‐Helene Saint‐Hilaire, Julie B. Schwartzbard, Wolfgang Singer, Michael J. Soileau, Steven Vernino, Patricio Millar Vernetti, Oleg Yerstein, Roy Freeman   +31 more
wiley   +1 more source

Altered interictal cerebral blood flow in generalized tonic-clonic seizure: an arterial spin labeling based MRI study

Chinese Journal of Contemporary Neurology and Neurosurgery, 2011
Objective To study the alteration of interictal cerebral blood flow (CBF) of patients with generalized tonic-clonic seizure (GTCS) by pulsed arterial spin labeling (PASL), and uncover the neuropathophysiological mechanism of GTCS.
Maoxue WANG, Zhiqiang ZHANG, Guangming LU, Cuiping YUAN, Zhengge WANG, Lianfang SHEN   +5 more
doaj  

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

The study of morphological changes and regional hemodynamics in pseudoexfoliative glaucoma

Oftalʹmologiâ, 2014
Aim. Comparative study of choroidea, retina ganglion cell complex (GCC) and regional hemodynamics in primary open angle (POAG) and pseudoexfoliative glaucoma (PEG) patients.Materials and methods. 40 POAG patients and 36 PEG patients with the same disease
N. I. Kurysheva, A. S. Apostolova, T. D. Ardzhevnishvili, T. N. Kiseleva, A. V. Fomin   +4 more
doaj   +3 more sources

The functional neuroimaging correlates of psychogenic versus organic dystonia [PDF]

, 2017
The neurobiological basis of psychogenic movement disorders remains poorly understood and the management of these conditions difficult. Functional neuroimaging studies have provided some insight into the pathophysiology of disorders implicating ...
Bhatia, Kailash P., Brown, Richard J., Frackowiak, Richard S. J., Mehta, Arpan R., Rowe, James B., Schrag, Anette E., Trimble, Michael R., Ward, Nicholas S.   +7 more
core  

Dehydration accelerates reductions in cerebral blood flow during prolonged exercise in the heat without compromising brain metabolism [PDF]

, 2015
Dehydration hastens the decline in cerebral blood flow (CBF) during incremental exercise, while the cerebral metabolic rate for oxygen (CMRO2) is preserved.
Benjamin Garcia, Gibbs EL, Iñaki Llodio, Johnson JM, José González-Alonso, Kameljit K. Kalsi, Niels H. Secher, Scott T. Chiesa, Steven J. Trangmar   +8 more
core   +2 more sources

FDG‐PET Associations With Disease Severity and Outcomes in NMDA‐Receptor IgG Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Patients with N‐methyl‐D‐aspartate (NMDA) receptor‐immunoglobulin G (IgG) autoimmune encephalitis (NMDAR‐IgG AE) demonstrate occipital lobe hypometabolism on baseline brain fluorodeoxyglucose‐positron emission tomography (bFDG‐PET).
Jonathan K. Lee, Jeffrey Lambe, Scott Johnson, Akua Abrah, Jennifer Bullen, Jeffrey A. Cohen, Tatchaporn Ongphichetmetha, Amy Kunchok   +7 more
wiley   +1 more source